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Biology and Biochemistry

D-Index
69
Citations
30612
World Ranking
7231
National Ranking
551

Overview

Dominique Bonnet is affiliated with The Francis Crick Institute in the United Kingdom. Their research primarily spans the fields of medicine and biochemistry, genetics, and molecular biology, with a considerable focus on hematology, molecular biology, genetics, immunology, and cancer research.

Their work extensively covers topics related to acute myeloid leukemia research, hematopoietic stem cell transplantation, myeloproliferative neoplasms including diagnosis and treatment, single-cell and spatial transcriptomics, immune cell function and interaction, hemoglobinopathies and related disorders, as well as cancer, hypoxia, and metabolism.

Dominique Bonnet has contributed to several recent publications, including the following papers:

  • Bone marrow niches in haematological malignancies (2020), published in Nature Reviews. Cancer
  • Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers (2020), published in The Lancet
  • Dynamic responses of the haematopoietic stem cell niche to diverse stresses (2020), published in Nature Cell Biology
  • Innovations, challenges, and minimal information for standardization of humanized mice (2020), published in EMBO Molecular Medicine
  • Mesenchymal niche remodeling impairs hematopoiesis via stanniocalcin 1 in acute myeloid leukemia (2020), published in Journal of Clinical Investigation

The scientist frequently collaborates with a number of coauthors who have contributed significantly alongside them. These include John G. Gribben, William Grey, Hector Huerga Encabo, Kevin Rouault-Pierre, and Syed A. Mian.

Dominique Bonnet publishes recurrently in a selection of scientific venues. The most frequent outlets for their work are:

  • Blood
  • Experimental Hematology
  • HemaSphere
  • Nature Communications
  • bioRxiv (Cold Spring Harbor Laboratory)

Best Publications

  • Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

    Dominique Bonnet;John E. Dick

  • Purification of primitive human hematopoietic cells capable of repopulating immune-deficient mice

    Mickie Bhatia;Jean C. Y. Wang;Ursula Kapp;Dominique Bonnet

  • A newly discovered class of human hematopoietic cells with SCID-repopulating activity

    Mickie Bhatia;Dominique Bonnet;Dominique Bonnet;Barbara Murdoch;Olga I. Gan

  • Cancer stem cell definitions and terminology: the devil is in the details

    Peter Valent;Dominique Bonnet;Ruggero De Maria;Tsvee Lapidot

  • Characterization of human DNGR-1+ BDCA3+ leukocytes as putative equivalents of mouse CD8alpha+ dendritic cells.

    Lionel Franz Poulin;Mariolina Salio;Emmanuel Griessinger;Fernando Anjos-Afonso

  • Mesenchymal stem cells inhibit proliferation and apoptosis of tumor cells: impact on in vivo tumor growth.

    R Ramasamy;E. W. F. Lam;I. Soeiro;Veronica Tisato

  • Quantitative analysis reveals expansion of human hematopoietic repopulating cells after short-term ex vivo culture.

    Mickie Bhatia;Dominique Bonnet;Ursula Kapp;Jean C.Y. Wang

  • Bone Morphogenetic Proteins Regulate the Developmental Program of Human Hematopoietic Stem Cells

    Mickie Bhatia;Dominique Bonnet;Dongmei Wu;Barbara Murdoch

  • Leukemia-initiating cells from some acute myeloid leukemia patients with mutated nucleophosmin reside in the CD34- fraction

    David C. Taussig;Jacques Vargaftig;Farideh Miraki-Moud;Emmanuel Griessinger

  • CD64 distinguishes macrophages from dendritic cells in the gut and reveals the Th1-inducing role of mesenteric lymph node macrophages during colitis

    Samira Tamoutounour;Samira Tamoutounour;Samira Tamoutounour;Sandrine Henri;Sandrine Henri;Sandrine Henri;Hugues Lelouard;Hugues Lelouard;Hugues Lelouard;Béatrice de Bovis;Béatrice de Bovis;Béatrice de Bovis

  • Anti-CD38 antibody-mediated clearance of human repopulating cells masks the heterogeneity of leukemia-initiating cells.

    David C. Taussig;Farideh Miraki-Moud;Fernando Anjos-Afonso;Daniel J. Pearce

  • Hematopoietic stem cells express multiple myeloid markers: implications for the origin and targeted therapy of acute myeloid leukemia

    David C. Taussig;Daniel J. Pearce;Catherine Simpson;Ama Z. Rohatiner

  • Characterization of cells with a high aldehyde dehydrogenase activity from cord blood and acute myeloid leukemia samples.

    Daniel J. Pearce;David Taussig;Catherine Simpson;Kirsty Allen

  • In vivo contribution of murine mesenchymal stem cells into multiple cell-types under minimal damage conditions.

    Fernando Anjos-Afonso;Elena K. Siapati;Dominique Bonnet

  • Expansion of human SCID-repopulating cells under hypoxic conditions.

    Guénahel H. Danet;Yi Pan;Jennifer L. Luongo;Dominique A. Bonnet

  • Bone marrow niches in haematological malignancies.

    Simón Méndez-Ferrer;Simón Méndez-Ferrer;Simón Méndez-Ferrer;Dominique Bonnet;David P. Steensma;Robert P. Hasserjian

  • β-Catenin mediates the establishment and drug resistance of MLL leukemic stem cells.

    Jenny Yeung;Maria Teresa Esposito;Arnaud Gandillet;Bernd B. Zeisig

  • Nonhematopoietic/endothelial SSEA-1+ cells define the most primitive progenitors in the adult murine bone marrow mesenchymal compartment

    Fernando Anjos-Afonso;Dominique Bonnet

  • Chimeric antigen receptors against CD33/CD123 antigens efficiently target primary acute myeloid leukemia cells in vivo

    I Pizzitola;Fernando Anjosafonso;Kevin Rouaultpierre;Francois Lassailly

  • Multiparameter analysis of murine bone marrow side population cells

    Daniel J. Pearce;Christopher M. Ridler;Catherine Simpson;Dominique Bonnet

Frequent Co-Authors

John G. Gribben
John G. Gribben Queen Mary University of London
Ghulam J. Mufti
Ghulam J. Mufti King's College London
Jude Fitzgibbon
Jude Fitzgibbon Queen Mary University of London
Nelly Frossard
Nelly Frossard University of Strasbourg
Jacques Haiech
Jacques Haiech University of Strasbourg
Christine Chomienne
Christine Chomienne Université Paris Cité
Andrea Biondi
Andrea Biondi University of Milano-Bicocca
Andrey S. Klymchenko
Andrey S. Klymchenko University of Strasbourg
John E. Dick
John E. Dick Princess Margaret Cancer Centre
Marc Humbert
Marc Humbert University of Paris-Saclay

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