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Biology and Biochemistry

D-Index
54
Citations
18106
World Ranking
15370
National Ranking
6417

Overview

Mary R. Avarbock is affiliated with the University of Pennsylvania in the United States and has contributed extensively to research in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work primarily focuses on Molecular Biology, Reproductive Medicine, and related subfields.

Their research explores key areas including:

  • Reproductive Biology and Fertility
  • Sperm and Testicular Function
  • Renal and related cancers
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Single-cell and spatial transcriptomics
  • Pluripotent Stem Cells Research
  • CRISPR and Genetic Engineering

Mary R. Avarbock's recent publications span a variety of topics in reproductive biology and molecular regulation of spermatogenesis. Notable recent papers include:

  • "FGF9 promotes mouse spermatogonial stem cell proliferation mediated by p38 MAPK signalling" (2020) published in Cell Proliferation
  • "Roles of Stra8 and Tcerg1l in retinoic acid induced spermatogonial differentiation in mouse" (2021) published in Biology of Reproduction
  • "Reestablishment of spermatogenesis after more than 20 years of cryopreservation of rat spermatogonial stem cells reveals an important impact in differentiation capacity" (2022) published in PLoS Biology
  • "Single-cell multiomic comparison of mouse and rat spermatogenesis reveals gene regulatory networks conserved for over 20 million years" (2025) published in Stem Cell Reports

Their frequent publication venues reflect a focus on cellular and molecular biology-related journals, including:

  • Cell Proliferation
  • Biology of Reproduction
  • PLoS Biology
  • Stem Cell Reports

Collaborations have been an integral part of their research, with frequent coauthors including:

  • Eoin C. Whelan
  • Ralph L. Brinster
  • Fan Yang
  • Daniel P. Beiting
  • Xuebing Guan

Their body of work integrates contributions from diverse subfields such as Molecular Biology, Public Health, Environmental and Occupational Health, Reproductive Medicine, and Genetics, which underscores a multidisciplinary approach to their scientific investigations.

Best Publications

  • Germline transmission of donor haplotype following spermatogonial transplantation.

    Ralph L. Brinster;Mary R. Avarbock

  • GROWTH FACTORS ESSENTIAL FOR SELF-RENEWAL AND EXPANSION OF MOUSE SPERMATOGONIAL STEM CELLS

    Hiroshi Kubota;Mary R. Avarbock;Ralph L. Brinster

  • β1- and α6-integrin are surface markers on mouse spermatogonial stem cells

    Takashi Shinohara;Mary R. Avarbock;Ralph L. Brinster

  • Transplantation of testis germinal cells into mouse seminiferous tubules.

    T Ogawa;J M Aréchaga;M R Avarbock;R L Brinster

  • Heterologous introns can enhance expression of transgenes in mice.

    Richard D. Palmiter;Eric P. Sandgren;Mary R. Avarbock;D. Diane Allen

  • Spermatogonial stem cells share some, but not all, phenotypic and functional characteristics with other stem cells.

    Hiroshi Kubota;Mary R. Avarbock;Ralph L. Brinster

  • Identifying genes important for spermatogonial stem cell self-renewal and survival

    Jon M. Oatley;Mary R. Avarbock;Aino I. Telaranta;Douglas T. Fearon

  • Rat spermatogenesis in mouse testis

    David E. Clouthier;Mary R. Avarbock;Shanna D. Maika;Robert E. Hammer

  • Spermatogonial stem cell enrichment by multiparameter selection of mouse testis cells.

    Takashi Shinohara;Kyle E. Orwig;Mary R. Avarbock;Ralph L. Brinster

  • Pattern and Kinetics of Mouse Donor Spermatogonial Stem Cell Colonization in Recipient Testes

    Makoto Nagano;Mary R. Avarbock;Ralph L. Brinster

  • Culture conditions and single growth factors affect fate determination of mouse spermatogonial stem cells

    Hiroshi Kubota;Mary R. Avarbock;Ralph L. Brinster

  • Transplantation of male germ line stem cells restores fertility in infertile mice.

    Takehiko Ogawa;Ina Dobrinski;Mary R. Avarbock;Ralph L. Brinster

  • Reconstitution of spermatogenesis from frozen spermatogonial stem cells

    Mary R. Avarbock;Clayton J. Brinster;Ralph L. Brinster

  • MAINTENANCE OF MOUSE MALE GERM LINE STEM CELLS IN VITRO

    Makoto Nagano;Buom-Yong Ryu;Clayton J. Brinster;Mary R. Avarbock

  • Transgenic mice produced by retroviral transduction of male germ-line stem cells.

    Makoto Nagano;Clayton J. Brinster;Kyle E. Orwig;Buom-Yong Ryu

  • Germ Cell Genotype Controls Cell Cycle during Spermatogenesis in the Rat

    Luiz R. França;Takehiko Ogawa;Mary R. Avarbock;Ralph L. Brinster

  • Culture of mouse spermatogonial stem cells

    Makoto Nagano;Mary R. Avarbock;Efren B. Leonida;Clayton J. Brinster

  • Glial Cell Line-derived Neurotrophic Factor Regulation of Genes Essential for Self-renewal of Mouse Spermatogonial Stem Cells Is Dependent on Src Family Kinase Signaling

    Jon M. Oatley;Mary R. Avarbock;Ralph L. Brinster

  • Conservation of spermatogonial stem cell self-renewal signaling between mouse and rat

    Buom-Yong Ryu;Hiroshi Kubota;Mary R. Avarbock;Ralph L. Brinster

  • Colony stimulating factor 1 is an extrinsic stimulator of mouse spermatogonial stem cell self-renewal.

    Jon M. Oatley;Melissa J. Oatley;Mary R. Avarbock;John W. Tobias

Frequent Co-Authors

Ralph L. Brinster
Ralph L. Brinster University of Pennsylvania
Kyle E. Orwig
Kyle E. Orwig University of Pittsburgh
John W. Tobias
John W. Tobias University of Pennsylvania
Takashi Shinohara
Takashi Shinohara Kyoto University
Ina Dobrinski
Ina Dobrinski University of Calgary
Lonnie D. Russell
Lonnie D. Russell Southern Illinois University School of Medicine
Luiz R. França
Luiz R. França Universidade Federal de Minas Gerais
Marisa S. Bartolomei
Marisa S. Bartolomei University of Pennsylvania
Richard D. Palmiter
Richard D. Palmiter University of Washington
Robert E. Hammer
Robert E. Hammer The University of Texas Southwestern Medical Center

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