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D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
13264
World Ranking
13707
National Ranking
5809

Overview

John W. Tobias is affiliated with the University of Pennsylvania in the United States. Their research spans across multiple fields primarily within Medicine and Biochemistry, Genetics, and Molecular Biology. They have contributed extensively to subfields including Molecular Biology, Oncology, Immunology, Surgery, and Epidemiology.

Their recent published papers include:

  • Ferroptosis of tumour neutrophils causes immune suppression in cancer (2022) published in Nature
  • A stromal Integrated Stress Response activates perivascular cancer-associated fibroblasts to drive angiogenesis and tumour progression (2022) published in Nature Cell Biology
  • Loss of ELF5-FBXW7 stabilizes IFNGR1 to promote the growth and metastasis of triple-negative breast cancer through interferon-γ signalling (2020) published in Nature Cell Biology
  • Dll1+ quiescent tumor stem cells drive chemoresistance in breast cancer through NF-κB survival pathway (2021) published in Nature Communications
  • Chromatin accessibility and histone acetylation in the regulation of competence in early development (2020) published in Developmental Biology

Their work addresses main research topics such as:

  • Immune cells in cancer
  • Pancreatic and Hepatic Oncology Research
  • Cancer Immunotherapy and Biomarkers
  • Epigenetics and DNA Methylation
  • Telomeres, Telomerase, and Senescence
  • Retinal Diseases and Treatments
  • Liver physiology and pathology

John W. Tobias frequently publishes in venues including Cancer Research, bioRxiv (Cold Spring Harbor Laboratory), Nature Cell Biology, Nature Communications, and JCI Insight.

Frequent collaborators in their research are Robert H. Vonderheide, Ben Z. Stanger, Nune Markosyan, Serge Y. Fuchs, and Snahlata Singh.

Best Publications

  • c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma

    Andrew P. Weng;John M. Millholland;Yumi Yashiro-Ohtani;Marie Laure Arcangeli

  • Microarray-based, high-throughput gene expression profiling of microRNAs

    Peter T Nelson;Don A Baldwin;L Marie Scearce;J Carl Oberholtzer

  • Tumor Cell-Intrinsic Factors Underlie Heterogeneity of Immune Cell Infiltration and Response to Immunotherapy

    Jinyang Li;Katelyn T. Byrne;Fangxue Yan;Taiji Yamazoe

  • Universality and structure of the N-end rule.

    D K Gonda;A Bachmair;A Bachmair;I Wünning;I Wünning;J W Tobias

  • The miRNA-Processing Enzyme Dicer Is Essential for the Morphogenesis and Maintenance of Hair Follicles

    Thomas Andl;Elizabeth P. Murchison;Fei Liu;Yuhang Zhang

  • A GATA-1-regulated microRNA locus essential for erythropoiesis

    Louis C. Dore;Julio D. Amigo;Camila O. dos Santos;Zhe Zhang

  • Bald scalp in men with androgenetic alopecia retains hair follicle stem cells but lacks CD200-rich and CD34-positive hair follicle progenitor cells

    Luis A. Garza;Chao-Chun Yang;Tailun Zhao;Hanz B. Blatt

  • Colony stimulating factor 1 is an extrinsic stimulator of mouse spermatogonial stem cell self-renewal.

    Jon M. Oatley;Melissa J. Oatley;Mary R. Avarbock;John W. Tobias

  • Ubiquitin-specific proteases of Saccharomyces cerevisiae. Cloning of UBP2 and UBP3, and functional analysis of the UBP gene family.

    R.T. Baker;J.W. Tobias;A Varshavsky

  • Antibiotic-based selection for bacterial genes that are specifically induced during infection of a host

    M J Mahan;J W Tobias;J M Slauch;J M Slauch;P C Hanna

  • MicroRNA-21 regulates the self-renewal of mouse spermatogonial stem cells

    Zhiyv Niu;Shaun M. Goodyear;Shilpa Rao;Xin Wu

  • Tribbles homolog 2 inactivates C/EBPα and causes acute myelogenous leukemia

    Karen Keeshan;Yiping He;Bas J. Wouters;Olga Shestova

  • Differential Expression of miRNAs in Papillary Thyroid Carcinoma Compared to Multinodular Goiter Using Formalin Fixed Paraffin Embedded Tissues

    Michael T. Tetzlaff;Aihua Liu;Xiaowei Xu;Stephen R. Master

  • Prepubertal human spermatogonia and mouse gonocytes share conserved gene expression of germline stem cell regulatory molecules

    Xin Wu;Jonathan A. Schmidt;Mary R. Avarbock;John W. Tobias

  • Cloning and functional analysis of the ubiquitin-specific protease gene UBP1 of Saccharomyces cerevisiae.

    J.W. Tobias;A. Varshavsky

  • Activation of β-catenin signaling programs embryonic epidermis to hair follicle fate

    Yuhang Zhang;Thomas Andl;Steven H. Yang;Monica Teta

  • LIGHT DAMAGE INDUCED CHANGES IN MOUSE RETINAL GENE EXPRESSION

    Lin Chen;Wayne Wu;Tzvete Dentchev;Yong Zeng

  • Expression profiling reveals meiotic male germ cell mRNAs that are translationally up- and down-regulated

    Naoko Iguchi;John W. Tobias;Norman B. Hecht

  • Fertile offspring derived from mouse spermatogonial stem cells cryopreserved for more than 14 years

    Xin Wu;Shaun M. Goodyear;Lara K. Abramowitz;Marisa S. Bartolomei

  • MicroRNA expression profiling outperforms mRNA expression profiling in formalin-fixed paraffin-embedded tissues.

    Aihua Liu;Michael T. Tetzlaff;Pat VanBelle;David Elder

Frequent Co-Authors

Ralph L. Brinster
Ralph L. Brinster University of Pennsylvania
Mary R. Avarbock
Mary R. Avarbock University of Pennsylvania
Christopher J. Lengner
Christopher J. Lengner University of Pennsylvania
Kim M. Olthoff
Kim M. Olthoff University of Pennsylvania
Jason D. Christie
Jason D. Christie University of Pennsylvania
Andres J. P. Klein-Szanto
Andres J. P. Klein-Szanto Fox Chase Cancer Center
Abraham Shaked
Abraham Shaked University of Pennsylvania
Peter S. Klein
Peter S. Klein University of Pennsylvania
Vivianna M. Van Deerlin
Vivianna M. Van Deerlin University of Pennsylvania
Joshua L. Dunaief
Joshua L. Dunaief University of Pennsylvania

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