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Biology and Biochemistry

D-Index
54
Citations
12011
World Ranking
15522
National Ranking
1222

Overview

Roger J. Keynes is affiliated with the University of Cambridge in the United Kingdom. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Neuroscience. Within these fields, their work touches on key subfields including Molecular Biology, Cell Biology, Cellular and Molecular Neuroscience, Developmental Neuroscience, and Neurology.

Keynes's research focuses on several main topics: nerve injury and regeneration, signaling pathways in disease, proteoglycans and glycosaminoglycans research, endoplasmic reticulum stress and disease, connexins and lens biology, axon guidance and neuronal signaling, and cellular mechanics and interactions.

Recent publications by Keynes and collaborators include:

  • Targeting chondroitinase ABC to axons enhances the ability of chondroitinase to promote neurite outgrowth and sprouting (2020, PLoS ONE)
  • Regulation of nerve growth and patterning by cell surface protein disulphide isomerase (2020, eLife)
  • Axons in the Chick Embryo Follow Soft Pathways Through Developing Somite Segments (2022, Frontiers in Cell and Developmental Biology)
  • Faculty Opinions recommendation of A unique macrophage subpopulation signals directly to progenitor cells to promote regenerative neurogenesis in the zebrafish spinal cord (2021, Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature)
  • Faculty Opinions recommendation of Structural Basis of Teneurin-Latrophilin Interaction in Repulsive Guidance of Migrating Neurons (2020, Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature)

Frequently publishing in venues such as Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature, PLoS ONE, eLife, and Frontiers in Cell and Developmental Biology, Keynes's work contributes to various aspects of developmental and molecular neuroscience.

Collaborators who have frequently co-authored papers with Keynes include Mansoor Raza, Julia Schaeffer, Priscilla Day, Nuno L. Alves, and Esther Daniell. Their joint work spans multiple publications, indicating ongoing research partnerships.

Best Publications

  • Peripheral nerve regeneration

    James W. Fawcett;Roger J. Keynes

  • Segmental patterns of neuronal development in the chick hindbrain.

    Andrew Lumsden;Roger Keynes

  • Segmentation in the chick embryo hindbrain is defined by cell lineage restrictions

    Scott Fraser;Roger Keynes;Andrew Lumsden

  • Segmentation in the vertebrate nervous system

    Roger J. Keynes;Claudio D. Stern

  • The migration of neural crest cells and the growth of motor axons through the rostral half of the chick somite.

    M. Rickmann;J. W. Fawcett;R. J. Keynes

  • Mechanisms of vertebrate segmentation

    Roger J. Keynes;Claudio D. Stern

  • Isolation from chick somites of a glycoprotein fraction that causes collapse of dorsal root ganglion growth cones.

    Jamie A. Davies;Geoffrey M.W. Cook;Claudio D. Stern;Roger J. Keynes

  • Axon guidance molecules

    Roger Keynes;Geoffrey M.W. Cook

  • A central role for the notochord in vertebral patterning

    Angeleen Fleming;Roger Keynes;David Tannahill

  • Segmentation and the origin of regional diversity in the vertebrate central nervous system.

    Roger Keynes;Roger Keynes;Andrew Lumsden;Andrew Lumsden

  • Interactions between somite cells: the formation and maintenance of segment boundaries in the chick embryo.

    C.D. Stern;R.J. Keynes

  • Hox genes and regionalization of the nervous system.

    Roger Keynes;Robb Krumlauf

  • Periodic segmental anomalies induced by heat shock in the chick embryo are associated with the cell cycle

    D. R. N. Primmett;W. E. Norris;G. J. Carlson;R. J. Keynes

  • Investigations into the mechanism by which sulfated polysaccharides inhibit HIV infection in vitro.

    Myra O. McCLURE;John P. Moore;Dominique F. Blanc;Paul Scotting

  • A cell lineage analysis of segmentation in the chick embryo

    Claudio D. Stern;Scott E. Fraser;Roger J. Keynes;Dennis R. N. Primmett

  • Muscle basal lamina: a new graft material for peripheral nerve repair

    James W. Fawcett;Roger J. Keynes

  • Interactions between neurites and somite cells: inhibition and stimulation of nerve growth in the chick embryo.

    Claudio D. Stern;Sanjay M. Sisodiya;Roger J. Keynes

  • Building the backbone: the development and evolution of vertebral patterning

    Angeleen Fleming;Marcia G Kishida;Charles B Kimmel;Roger J Keynes

  • A critical role for sonic hedgehog signaling in the early expansion of the developing brain.

    Joanne Britto;David Tannahill;Roger Keynes

  • The role of Schwann cells in the regeneration of peripheral nerve axons through muscle basal lamina grafts.

    M.R. Feneley;J.W. Fawcett;R.J. Keynes

Frequent Co-Authors

Claudio D. Stern
Claudio D. Stern University College London
David Tannahill
David Tannahill University of Cambridge
James W. Fawcett
James W. Fawcett University of Cambridge
Andrew Lumsden
Andrew Lumsden King's College London
Jamie A. Davies
Jamie A. Davies University of Edinburgh
Scott E. Fraser
Scott E. Fraser University of Southern California
Christine E. Holt
Christine E. Holt University of Cambridge
Andreas Faissner
Andreas Faissner Ruhr University Bochum
Joost Verhaagen
Joost Verhaagen Netherlands Institute for Neuroscience
Herbert M. Geller
Herbert M. Geller National Institutes of Health

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