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Neuroscience

D-Index
41
Citations
7061
World Ranking
7839
National Ranking
593

Overview

Sarah Guthrie is affiliated with the University of Sussex in the United Kingdom and conducts research primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans several interconnected subfields including Molecular Biology, Cellular and Molecular Neuroscience, Epidemiology, Surgery, and Hepatology.

The research topics Sarah Guthrie focuses on encompass Axon Guidance and Neuronal Signaling, Developmental Biology and Gene Regulation, Zebrafish Biomedical Research Applications, Ophthalmology and Visual Impairment Studies, Ocular Surface and Contact Lens, Liver Disease Diagnosis and Treatment, and Hedgehog Signaling Pathway Studies.

Recent publications reflect a range of interests related to neuroscience, molecular biology, and vision science. Notable recent papers include:

  • Cadherins regulate nuclear topography and function of developing ocular motor circuitry, 2020, eLife
  • The Rac-GAP alpha2-Chimaerin Signals via CRMP2 and Stathmins in the Development of the Ocular Motor System, 2021, Journal of Neuroscience
  • C9orf72 poly GA RAN-translated protein plays a key role in amyotrophic lateral sclerosis via aggregation and toxicity, 2020, Human Molecular Genetics
  • Optical characterisation and vision quality assessment of two myopia control contact lenses, 2025, Ophthalmic and Physiological Optics
  • Cadherins regulate nuclear topography and function of developing ocular motor circuitry, 2020, bioRxiv (Cold Spring Harbor Laboratory)

The scientist frequently collaborates with several coauthors, including Jill Woods, Athene Knüfer, Giovanni Diana, Gregory S. Walsh, and Jonathan D. W. Clarke.

Publication venues where Sarah Guthrie has frequently contributed include Poster presentations, Contact Lens and Anterior Eye, eLife, Journal of Neuroscience, and Ophthalmic and Physiological Optics.

Best Publications

  • Determination of neuroepithelial cell fate: Induction of the oligodendrocyte lineage by ventral midline cells and sonic hedgehog

    Nigel P. Pringle;Wei-Ping Yu;Sarah Guthrie;Henk Roelink

  • Formation and regeneration of rhombomere boundaries in the developing chick hindbrain.

    Sarah Guthrie;Andrew Lumsden

  • Motor Axon Subpopulations Respond Differentially to the Chemorepellents Netrin-1 and Semaphorin D

    Alfredo Varela-Echavarría;Anna Tucker;Andreas W. Püschel;Sarah Guthrie

  • Modulation of gap junction transcript and protein expression during pregnancy in the rat.

    Boris Risek;Sarah Guthrie;Nalin M. Kumar;Norton B. Gilula

  • Gap junctional communication and development

    Sarah C. Guthrie;Norton B. Gilula

  • Patterning and axon guidance of cranial motor neurons

    Sarah Guthrie

  • Differential Expression of LIM Homeobox Genes among Motor Neuron Subpopulations in the Developing Chick Brain Stem

    Alfredo Varela-Echavarría;Samuel L. Pfaff;Sarah Guthrie

  • Multiple roles for FGF-3 during cranial neural development in the chicken.

    Radma Mahmood;Paul Kiefer;Sarah Guthrie;Clive Dickson

  • Neuroectodermal autonomy of Hox-2.9 expression revealed by rhombomere transpositions

    Sarah Guthrie;Ian Muchamore;Ian Muchamore;Atsushi Kuroiwa;Atsushi Kuroiwa;Heather Marshall;Heather Marshall

  • Human CHN1 Mutations Hyperactivate α2-Chimaerin and Cause Duane's Retraction Syndrome

    Noriko Miyake;Noriko Miyake;John Chilton;Maria Psatha;Long Cheng;Long Cheng

  • Patterns of cell division and interkinetic nuclear migration in the chick embryo hindbrain

    Sarah Guthrie;Matthew Butcher;Andrew Lumsden

  • The branchial arches and HGF are growth-promoting and chemoattractant for cranial motor axons

    Adele Caton;Adam Hacker;Arifa Naeem;Jean Livet

  • Dorsal Spinal Cord Neuroepithelium Generates Astrocytes but Not Oligodendrocytes

    Nigel P Pringle;Sarah Guthrie;Andrew Lumsden;William D Richardson

  • Chemorepulsion of developing motor axons by the floor plate

    Sarah Guthrie;Adrian Pini

  • Motor neuron pathfinding following rhombomere reversals in the chick embryo hindbrain.

    Sarah Guthrie;Andrew Lumsden

  • Reciprocal gene replacements reveal unique functions for Phox2 genes during neural differentiation.

    Eva Coppola;Alexandre Pattyn;Sarah C Guthrie;Christo Goridis

  • Patterns of junctional communication in the early amphibian embryo

    Sarah C. Guthrie

  • Slit-mediated repulsion is a key regulator of motor axon pathfinding in the hindbrain.

    Rachel Hammond;Valerie Vivancos;Arifa Naeem;John Chilton

  • Two regulatory genes, cNkx5-1 and cPax2, show different responses to local signals during otic placode and vesicle formation in the chick embryo

    Heike Herbrand;Sarah Guthrie;Thorsten Hadrys;Sonja Hoffmann

  • Wnt activity guides facial branchiomotor neuron migration, and involves the PCP pathway and JNK and ROCK kinases

    Valerie Vivancos;Ping Helen Chen;Nathalie Spassky;Dong Qian

  • Cranial expression of class 3 secreted semaphorins and their neuropilin receptors.

    John K. Chilton;Sarah Guthrie

  • Molecules making waves in axon guidance.

    A VarelaEchavarria;Sarah Guthrie

Frequent Co-Authors

Christopher Shaw
Christopher Shaw King's College London
Mustafa Sahin
Mustafa Sahin Boston Children's Hospital
Michèle Studer
Michèle Studer Université Côte d'Azur
Sian Ellard
Sian Ellard University of Exeter
Rüdiger Klein
Rüdiger Klein Max Planck Society
Samuel L. Pfaff
Samuel L. Pfaff Salk Institute for Biological Studies
Alain Chédotal
Alain Chédotal Institut de la Vision
Fujio Murakami
Fujio Murakami Osaka University

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