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J. Gregory Cairncross

J. Gregory Cairncross

D-Index & Metrics

Medicine

D-Index
77
Citations
70242
World Ranking
18221
National Ranking
767

Research.com Recognitions

  • 2009 - Fellow of the Royal Society of Canada Academy of Science

Overview

J. Gregory Cairncross is affiliated with the University of Calgary in Canada. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a particular focus on Genetics, Molecular Biology, Cancer Research, Radiology, Nuclear Medicine and Imaging, and Oncology.

The scientist's work centers on several key topics, including:

  • Glioma Diagnosis and Treatment
  • Brain Metastases and Treatment
  • Single-cell and spatial transcriptomics
  • Cancer Genomics and Diagnostics
  • Radiomics and Machine Learning in Medical Imaging
  • Microtubule and mitosis dynamics
  • Epigenetics and DNA Methylation

Among their recent publications are:

  • "Glioma-derived IL-33 orchestrates an inflammatory brain tumor microenvironment that accelerates glioma progression," 2020, Nature Communications
  • "Single-cell landscapes of primary glioblastomas and matched explants and cell lines show variable retention of inter- and intratumor heterogeneity," 2022, Cancer Cell
  • "CODEL: phase III study of RT, RT + TMZ, or TMZ for newly diagnosed 1p/19q codeleted oligodendroglioma. Analysis from the initial study design," 2020, Neuro-Oncology
  • "Joint Final Report of EORTC 26951 and RTOG 9402: Phase III Trials With Procarbazine, Lomustine, and Vincristine Chemotherapy for Anaplastic Oligodendroglial Tumors," 2022, Journal of Clinical Oncology
  • "Temozolomide and seizure outcomes in a randomized clinical trial of elderly glioblastoma patients," 2020, Journal of Neuro-Oncology

Publication venues in which Cairncross has frequently contributed include Neuro-Oncology, Neuro-Oncology Advances, Journal of Neuro-Oncology, bioRxiv (Cold Spring Harbor Laboratory), and Nature Communications.

Frequent co-authors in Cairncross's research include:

  • Michael Blough
  • Jennifer A. Chan
  • Mathieu Meode
  • Wolfgang Wick
  • Alba A. Brandes

In recognition of their contributions, Cairncross was named a Fellow of the Royal Society of Canada in 2009 under the Academy of Science category.

Best Publications

  • Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma

    Roger Stupp;Warren P. Mason;Martin J. van den Bent;Michael Weller

  • Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

    Roger Stupp;Monika E. Hegi;Warren P. Mason;Martin J. van den Bent

  • MGMT Gene Silencing and Benefit from Temozolomide in Glioblastoma

    Monika E Hegi;Annie-Claire Diserens;Thierry Gorlia;Marie-France Hamou

  • Specific Genetic Predictors of Chemotherapeutic Response and Survival in Patients With Anaplastic Oligodendrogliomas

    J G Cairncross;K Ueki;M C Zlatescu;D K Lisle

  • Gene expression-based classification of malignant gliomas correlates better with survival than histological classification.

    Catherine L. Nutt;D. R. Mani;Rebecca A. Betensky;Pablo Tamayo

  • Short-Course Radiation plus Temozolomide in Elderly Patients with Glioblastoma

    James R. Perry;Normand Laperriere;Christopher J. O'Callaghan;Alba A. Brandes

  • Abbreviated Course of Radiation Therapy in Older Patients With Glioblastoma Multiforme: A Prospective Randomized Clinical Trial

    Wilson Roa;P. M.A. Brasher;G. Bauman;M. Anthes

  • Practice parameter: Anticonvulsant prophylaxis in patients with newly diagnosed brain tumors Report of the Quality Standards Subcommittee of the American Academy of Neurology

    M. J. Glantz;B. F. Cole;B. F. Cole;P. A. Forsyth;L. D. Recht;L. D. Recht

  • Stem Cell–Related “Self-Renewal” Signature and High Epidermal Growth Factor Receptor Expression Associated With Resistance to Concomitant Chemoradiotherapy in Glioblastoma

    Anastasia Murat;Eugenia Migliavacca;Thierry Gorlia;Wanyu L Lambiv

  • Nomograms for predicting survival of patients with newly diagnosed glioblastoma: prognostic factor analysis of EORTC and NCIC trial 26981-22981/CE.3

    Thierry Gorlia;Martin J van den Bent;Monika E Hegi;Monika E Hegi;René O Mirimanoff

  • Molecular Subtypes of Anaplastic Oligodendroglioma: Implications for Patient Management at Diagnosis

    Yasushi Ino;Rebecca A. Betensky;Magdalena C. Zlatescu;Hikaru Sasaki

  • Radation therapy for brain metastases

    J. Gregory Cairncross;Jae‐Ho Kim;Jerome B. Posner

  • Changing Paradigms—An Update on the Multidisciplinary Management of Malignant Glioma

    Roger Stupp;Monika E. Hegi;Martin J. van den Bent;Warren P. Mason

  • Benefit From Procarbazine, Lomustine, and Vincristine in Oligodendroglial Tumors Is Associated With Mutation of IDH

    J. Gregory Cairncross;Meihua Wang;Robert B. Jenkins;Edward G. Shaw

  • A multigene predictor of outcome in glioblastoma.

    Howard Colman;Li Zhang;Erik P. Sulman;J. Matthew McDonald

  • Glioma Classification: A Molecular Reappraisal

    David N. Louis;Eric C. Holland;J. Gregory Cairncross

  • Successful chemotherapy for recurrent malignant oligodendroglioma

    J. Gregory Cairncross;David R. Macdonald

  • cIMPACT-NOW update 2: diagnostic clarifications for diffuse midline glioma, H3 K27M-mutant and diffuse astrocytoma/anaplastic astrocytoma, IDH-mutant

    David N. Louis;Caterina Giannini;David Capper;Werner Paulus

  • Supratentorial malignant glioma: patterns of recurrence and implications for external beam local treatment.

    Laurie E. Gaspar;Barbara J. Fisher;David R. Macdonald;Deborah V. Leber

  • Concurrent CIC mutations, IDH mutations, and 1p/19q loss distinguish oligodendrogliomas from other cancers.

    Stephen Yip;Yaron S. Butterfield;Olena Morozova;Suganthi Chittaranjan

Frequent Co-Authors

Samuel Weiss
Samuel Weiss University of Calgary
David N. Louis
David N. Louis Harvard University
Jennifer A. Chan
Jennifer A. Chan University of Calgary
Wolfgang Wick
Wolfgang Wick German Cancer Research Center
Stephen M. Robbins
Stephen M. Robbins University of Calgary
Martin J. van den Bent
Martin J. van den Bent Erasmus University Rotterdam
Minesh P. Mehta
Minesh P. Mehta University of Maryland, Baltimore
Marco A. Marra
Marco A. Marra University of British Columbia
Lisa M. DeAngelis
Lisa M. DeAngelis Memorial Sloan Kettering Cancer Center
Roger Stupp
Roger Stupp Northwestern University

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