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Biology and Biochemistry

D-Index
93
Citations
39468
World Ranking
2072
National Ranking
134

Research.com Recognitions

  • 2013 - Fellow of the Royal Society, United Kingdom
  • 1962 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1934 - Fellow of the American Association for the Advancement of Science (AAAS)
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Fellow of The Academy of Medical Sciences, United Kingdom

Overview

William D. Richardson is affiliated with University College London in the United Kingdom. Their research spans several interconnected fields within neuroscience and molecular biology, focusing on the development and function of oligodendrocytes and their influence on neural mechanisms.

Their work covers a range of topics including:

  • Neurogenesis and neuroplasticity mechanisms
  • Neuroinflammation and neurodegeneration mechanisms
  • Memory and neural mechanisms
  • Zebrafish biomedical research applications
  • Regulation of appetite and obesity
  • Epigenetics and DNA methylation
  • Neonatal respiratory health research

Main fields of study include Neuroscience and Biochemistry, Genetics and Molecular Biology. Subfields of particular focus are Developmental Neuroscience, Molecular Biology, Neurology, Cognitive Neuroscience, and Endocrine and Autonomic Systems.

Among the frequent venues where Richardson has published are bioRxiv (Cold Spring Harbor Laboratory), Glia, Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature, Seminars in Cell and Developmental Biology, and Cell Reports.

Some notable recent papers authored or co-authored by Richardson are:

  • Life-long oligodendrocyte development and plasticity (2021) in Seminars in Cell and Developmental Biology
  • Nutritional regulation of oligodendrocyte differentiation regulates perineuronal net remodeling in the median eminence (2021) in Cell Reports
  • Oligodendrocyte dynamics dictate cognitive performance outcomes of working memory training in mice (2023) in Nature Communications
  • Developmental origin of oligodendrocytes determines their function in the adult brain (2024) in Nature Neuroscience
  • Median eminence myelin continuously turns over in adult mice (2023) in Molecular Metabolism

Frequent co-authors who have collaborated with Richardson include Takahiro Shimizu, Huiliang Li, Stuart G. Nayar, Sophie Buller, and Clémence Blouet.

The scientist has been recognized by several scholarly societies and holds fellowships including:

  • Fellow of the Royal Society, United Kingdom (2013)
  • Fellow of the American Association for the Advancement of Science (AAAS) (1962)
  • Fellow of the American Association for the Advancement of Science (AAAS) (1934)
  • Fellow of The Academy of Medical Sciences, United Kingdom

Best Publications

  • A short amino acid sequence able to specify nuclear location

    Daniel Kalderon;Bruce L. Roberts;William D. Richardson;Alan E. Smith

  • Cell death and control of cell survival in the oligodendrocyte lineage

    B.A. Barres;I.K. Hart;H.S.R. Coles;J.F. Burne

  • Sequence requirements for nuclear location of simian virus 40 large-T antigen.

    Daniel Kalderon;William D. Richardson;Alexander F. Markham;Alan E. Smith

  • Competing waves of oligodendrocytes in the forebrain and postnatal elimination of an embryonic lineage.

    Nicoletta Kessaris;Matthew Fogarty;Palma Iannarelli;Matthew Grist

  • Neural crest origins of the neck and shoulder

    Toshiyuki Matsuoka;Per E. Ahlberg;Nicoletta Kessaris;Palma Iannarelli

  • Oligodendrocyte heterogeneity in the mouse juvenile and adult central nervous system.

    Sueli Marques;Amit Zeisel;Simone Codeluppi;David van Bruggen

  • PDGFRA/NG2 glia generate myelinating oligodendrocytes and piriform projection neurons in adult mice

    Leanne E Rivers;Kaylene M Young;Matteo Rizzi;Françoise Jamen

  • A role for platelet-derived growth factor in normal gliogenesis in the central nervous system

    William D. Richardson;Nigel Pringle;Michael J. Mosley;Bengt Westermark

  • Platelet-derived growth factor from astrocytes drives the clock that times oligodendrocyte development in culture.

    Martin C. Raff;Laura E. Lillien;William D. Richardson;Julia F. Burne

  • Astrocytes and disease: a neurodevelopmental perspective

    Anna V. Molofsky;Robert Krenick;Erik Ullian;Hui-hsin Tsai

  • CNS-resident glial progenitor/stem cells produce Schwann cells as well as oligodendrocytes during repair of CNS demyelination.

    Malgorzata Zawadzka;Malgorzata Zawadzka;Leanne E. Rivers;Stephen P.J. Fancy;Stephen P.J. Fancy;Chao Zhao

  • Nuclear protein migration involves two steps: rapid binding at the nuclear envelope followed by slower translocation through nuclear pores.

    W.D. Richardson;A.D. Mills;S.M. Dilworth;R.A. Laskey

  • Oligodendrocyte Population Dynamics and the Role of PDGF In Vivo

    Andrew R Calver;Anita C Hall;Wei-Ping Yu;Frank S Walsh

  • A singularity of PDGF alpha-receptor expression in the dorsoventral axis of the neural tube may define the origin of the oligodendrocyte lineage

    Nigel P. Pringle;William D. Richardson

  • Oligodendrocyte Development and Plasticity

    Dwight E. Bergles;William D. Richardson

  • Regional Astrocyte Allocation Regulates CNS Synaptogenesis and Repair

    Hui-Hsin Tsai;Huiliang Li;Luis C. Fuentealba;Anna V. Molofsky

  • Defective oligodendrocyte development and severe hypomyelination in PDGF-A knockout mice

    Marcus Fruttiger;Linda Karlsson;Anita C. Hall;Alexandra Abramsson

  • PDGF receptors in the rat CNS: during late neurogenesis, PDGF alpha-receptor expression appears to be restricted to glial cells of the oligodendrocyte lineage.

    N.P. Pringle;H.S. Mudhar;E.J. Collarini;W.D. Richardson

  • Rapid production of new oligodendrocytes is required in the earliest stages of motor-skill learning

    Lin Xiao;David Ohayon;Ian A McKenzie;Alexander Sinclair-Wilson

  • Hedgehog-dependent oligodendrocyte lineage specification in the telencephalon.

    Nicoletta Tekki-Kessaris;Rachel Woodruff;Rachel Woodruff;Anita C. Hall;Anita C. Hall;William Gaffield;William Gaffield

Frequent Co-Authors

Nicoletta Kessaris
Nicoletta Kessaris University College London
Martin Raff
Martin Raff University College London
David Attwell
David Attwell University College London
David H. Rowitch
David H. Rowitch University of Cambridge
Robin J.M. Franklin
Robin J.M. Franklin University of Cambridge
Werner Seeger
Werner Seeger University of Giessen
Alan E. Smith
Alan E. Smith Sanofi (United States)
Heiner Westphal
Heiner Westphal National Institutes of Health
Rory E. Morty
Rory E. Morty Max Planck Society
Charles D. Stiles
Charles D. Stiles Harvard University

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