World's Best Scientists 2026 revealed!
Charles ffrench-Constant

Charles ffrench-Constant

D-Index & Metrics

Biology and Biochemistry

D-Index
97
Citations
29634
World Ranking
1772
National Ranking
116

Charles ffrench-Constant publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Charles ffrench-Constant sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 242 publications — 65th percentile

65% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Charles ffrench-Constant D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Charles ffrench-Constant sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 97 D-Index — 91st percentile

91% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • 2018 - Fellow of the Royal Society of Edinburgh
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Fellow of The Academy of Medical Sciences, United Kingdom

Overview

Charles ffrench-Constant is a researcher affiliated with the University of Edinburgh in the United Kingdom. Their work predominantly spans the fields of Biochemistry, Genetics and Molecular Biology, as well as Neuroscience, with notable contributions across subfields including Molecular Biology, Developmental Neuroscience, Cellular and Molecular Neuroscience, Neurology, and Genetics.

The researcher focuses on several main topics of study, which include:

  • Neurogenesis and neuroplasticity mechanisms
  • Neuroinflammation and Neurodegeneration Mechanisms
  • RNA regulation and disease
  • RNA Research and Splicing
  • Connexins and lens biology
  • Multiple Sclerosis Research Studies
  • Nerve injury and regeneration

Among the frequent co-authors in their publications are Peter Connick, Steffen Mayerl, Siddharthan Chandran, David A. Lyons, and Marie E. Bechler.

They have published extensively in various venues, with notable frequency in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Developmental Cell
  • BIO-PROTOCOL
  • Nature Reviews Neurology
  • The Lancet Neurology

Representative recent papers by Charles ffrench-Constant include:

  • "Hypomyelinating leukodystrophies - unravelling myelin biology," 2020, published in Nature Reviews Neurology
  • "Safety and efficacy of bexarotene in patients with relapsing-remitting multiple sclerosis (CCMR One): a randomised, double-blind, placebo-controlled, parallel-group, phase 2a study," 2021, published in The Lancet Neurology
  • "iPSC-derived myelinoids to study myelin biology of humans," 2021, published in Developmental Cell
  • "Selective PDE4 subtype inhibition provides new opportunities to intervene in neuroinflammatory versus myelin damaging hallmarks of multiple sclerosis," 2022, published in Brain Behavior and Immunity
  • "PI 3-kinase delta enhances axonal PIP3 to support axon regeneration in the adult CNS," 2020, published in EMBO Molecular Medicine

They have been recognized through awards including election as a Fellow of the Royal Society of Edinburgh in 2018 and as a Fellow of The Academy of Medical Sciences, United Kingdom.

Best Publications

  • Remyelination in the CNS: from biology to therapy

    Robin J. M. Franklin;Charles ffrench-Constant

  • M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination

    Veronique E. Miron;Amanda Boyd;Jing Wei Zhao;Tracy J. Yuen;Tracy J. Yuen

  • Reappearance of an embryonic pattern of fibronectin splicing during wound healing in the adult rat.

    C Ffrench-Constant;L Van de Water;H F Dvorak;R O Hynes

  • Altered human oligodendrocyte heterogeneity in multiple sclerosis

    Sarah Jäkel;Eneritz Agirre;Ana Mendanha Falcão;David van Bruggen

  • Retinoid X receptor gamma signaling accelerates CNS remyelination

    Jeffrey K Huang;Andrew A Jarjour;Brahim Nait Oumesmar;Christophe Kerninon

  • Regenerating CNS myelin — from mechanisms to experimental medicines

    Robin J M Franklin;Charles Ffrench-Constant

  • Evidence for specific cognitive deficits in preclinical Huntington's disease.

    Andrew David Lawrence;J. R. Hodges;Anne Elizabeth Rosser;A. Kershaw

  • Proliferating bipotential glial progenitor cells in adult rat optic nerve

    Charles ffrench-Constant;Martin C. Raff

  • The Chemokine Receptor CXCR2 Controls Positioning of Oligodendrocyte Precursors in Developing Spinal Cord by Arresting Their Migration

    Hui Hsin Tsai;Emma Frost;Vivien To;Shenandoah Robinson

  • Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration

    Alexander Raven;Wei-Yu Lu;Tak Yung Man;Sofia Ferreira-Gonzalez

  • Disease-specific oligodendrocyte lineage cells arise in multiple sclerosis

    Ana Mendanha Falcão;David van Bruggen;Sueli Marques;Mandy Meijer

  • Generation of an environmental niche for neural stem cell development by the extracellular matrix molecule tenascin C.

    Emmanuel Garcion;Aida Halilagic;Andreas Faissner;Charles ffrench-Constant

  • CNS Myelin Sheath Lengths Are an Intrinsic Property of Oligodendrocytes

    Marie E. Bechler;Lauren Byrne;Charles ffrench-Constant

  • Individual Oligodendrocytes Have Only a Few Hours in which to Generate New Myelin Sheaths In Vivo

    Tim Czopka;Charles ffrench-Constant;David A. Lyons

  • Neuregulin and BDNF induce a switch to NMDA receptor-dependent myelination by oligodendrocytes.

    Iben Lundgaard;Aryna Luzhynskaya;John H. Stockley;Zhen Wang

  • β1 integrins activate a MAPK signalling pathway in neural stem cells that contributes to their maintenance

    Lia S. Campos;Dino P. Leone;Joao B. Relvas;Cord Brakebusch

  • Mice lacking the giant protocadherin mFAT1 exhibit renal slit junction abnormalities and a partially penetrant cyclopia and anophthalmia phenotype.

    Lorenza Ciani;Anjila Patel;Nicholas Denby Allen;Charles ffrench-Constant

  • Neuroprotection and repair in multiple sclerosis

    Robin J. M. Franklin;Charles ffrench-Constant;Julia M. Edgar;Kenneth J. Smith

  • Alternative splicing of fibronectin is temporally and spatially regulated in the chicken embryo

    C. Ffrench-Constant;R.O. Hynes

  • A developmental analysis of oligodendroglial integrins in primary cells: changes in alpha v-associated beta subunits during differentiation.

    R. Milner;C. Ffrench-Constant

Frequent Co-Authors

Robin J.M. Franklin
Robin J.M. Franklin University of Cambridge
Andreas Faissner
Andreas Faissner Ruhr University Bochum
James W. Fawcett
James W. Fawcett University of Cambridge
Richard Milner
Richard Milner San Diego Biomedical Research Institute
Chao Zhao
Chao Zhao University of Cambridge
Wia Baron
Wia Baron University Medical Center Groningen
Diana Baralle
Diana Baralle University of Southampton
Siddharthan Chandran
Siddharthan Chandran University of Edinburgh
Mark P. Mattson
Mark P. Mattson Johns Hopkins University
David A. Lyons
David A. Lyons University of Edinburgh

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