2018 - Fellow of the Royal Society of Edinburgh
Fellow of The Academy of Medical Sciences, United Kingdom
His primary scientific interests are in Cell biology, Oligodendrocyte, Integrin, Neuroscience and Remyelination. His Cell biology research includes themes of Embryonic stem cell, Neurosphere and Cellular differentiation. His work carried out in the field of Oligodendrocyte brings together such families of science as Immunology and Spinal cord.
His Integrin research integrates issues from Extracellular matrix, Growth factor and Cell growth. His Neuroscience research incorporates elements of Multiple sclerosis, Movement disorders and Degenerative disease. His Remyelination research is multidisciplinary, incorporating elements of Axon and Neuroglia.
Charles ffrench-Constant mostly deals with Cell biology, Neuroscience, Oligodendrocyte, Integrin and Myelin. His work deals with themes such as Cellular differentiation and Immunology, which intersect with Cell biology. Much of his study explores Neuroscience relationship to Neuregulin.
His Oligodendrocyte research is multidisciplinary, incorporating perspectives in Tenascin C, Platelet-derived growth factor receptor, Neuroglia and Transplantation. His Integrin study combines topics in areas such as Laminin, Molecular biology, Signal transduction and Growth factor. His Remyelination study integrates concerns from other disciplines, such as Multiple sclerosis, Regeneration and CNS demyelination.
Charles ffrench-Constant focuses on Cell biology, Myelin, Neuroscience, Oligodendrocyte and Remyelination. His studies in Cell biology integrate themes in fields like Retinitis pigmentosa and Induced pluripotent stem cell. His study looks at the relationship between Myelin and topics such as Immunology, which overlap with Radiation therapy and Cancer research.
His research in the fields of Central nervous system and Hippocampus overlaps with other disciplines such as White matter and Mechanism. The Oligodendrocyte study combines topics in areas such as Myelin sheath, Multiple sclerosis, Node of Ranvier, Transplantation and Cell polarity. His research investigates the connection between Neuroepithelial cell and topics such as Integrin that intersect with problems in Cellular differentiation.
Charles ffrench-Constant mainly investigates Cell biology, Neuroscience, Myelin, Oligodendrocyte and Stem cell. Charles ffrench-Constant integrates Cell biology with Antigen processing in his study. His research integrates issues of Translational research, Clinical trial, Neurodegeneration and Gene expression profiling in his study of Neuroscience.
His Myelin study incorporates themes from Progenitor cell, Major histocompatibility complex and Experimental autoimmune encephalomyelitis. His studies deal with areas such as Myelin sheaths, Multiple sclerosis, Cognitive science and Developmental neurobiology as well as Oligodendrocyte. His Stem cell research includes elements of Embryonic stem cell and Adult stem cell.
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Remyelination in the CNS: from biology to therapy
Robin J. M. Franklin;Charles ffrench-Constant.
Nature Reviews Neuroscience (2008)
M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination
Veronique E. Miron;Amanda Boyd;Jing Wei Zhao;Tracy J. Yuen;Tracy J. Yuen.
Nature Neuroscience (2013)
Evidence for specific cognitive deficits in preclinical Huntington's disease.
Andrew David Lawrence;J. R. Hodges;Anne Elizabeth Rosser;A. Kershaw.
Brain (1998)
Retinoid X receptor gamma signaling accelerates CNS remyelination
Jeffrey K Huang;Andrew A Jarjour;Brahim Nait Oumesmar;Christophe Kerninon.
Nature Neuroscience (2011)
The Chemokine Receptor CXCR2 Controls Positioning of Oligodendrocyte Precursors in Developing Spinal Cord by Arresting Their Migration
Hui Hsin Tsai;Emma Frost;Vivien To;Shenandoah Robinson.
Cell (2002)
Regenerating CNS myelin — from mechanisms to experimental medicines
Robin J M Franklin;Charles Ffrench-Constant.
Nature Reviews Neuroscience (2017)
Generation of an environmental niche for neural stem cell development by the extracellular matrix molecule tenascin C.
Emmanuel Garcion;Aida Halilagic;Andreas Faissner;Charles ffrench-Constant.
Development (2004)
Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration
Alexander Raven;Wei-Yu Lu;Tak Yung Man;Sofia Ferreira-Gonzalez.
Nature (2017)
Pathogenesis of multiple sclerosis.
C ffrench-Constant.
The Lancet (1994)
β1 integrins activate a MAPK signalling pathway in neural stem cells that contributes to their maintenance
Lia S. Campos;Dino P. Leone;Joao B. Relvas;Cord Brakebusch.
Development (2004)
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