D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 86 Citations 21,775 203 World Ranking 1953 National Ranking 135

Research.com Recognitions

Awards & Achievements

2018 - Fellow of the Royal Society of Edinburgh

Fellow of The Academy of Medical Sciences, United Kingdom

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Genetics
  • Internal medicine

His primary scientific interests are in Cell biology, Oligodendrocyte, Integrin, Neuroscience and Remyelination. His Cell biology research includes themes of Embryonic stem cell, Neurosphere and Cellular differentiation. His work carried out in the field of Oligodendrocyte brings together such families of science as Immunology and Spinal cord.

His Integrin research integrates issues from Extracellular matrix, Growth factor and Cell growth. His Neuroscience research incorporates elements of Multiple sclerosis, Movement disorders and Degenerative disease. His Remyelination research is multidisciplinary, incorporating elements of Axon and Neuroglia.

His most cited work include:

  • Remyelination in the CNS: from biology to therapy (1059 citations)
  • M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination (913 citations)
  • Retinoid X receptor gamma signaling accelerates CNS remyelination (360 citations)

What are the main themes of his work throughout his whole career to date?

Charles ffrench-Constant mostly deals with Cell biology, Neuroscience, Oligodendrocyte, Integrin and Myelin. His work deals with themes such as Cellular differentiation and Immunology, which intersect with Cell biology. Much of his study explores Neuroscience relationship to Neuregulin.

His Oligodendrocyte research is multidisciplinary, incorporating perspectives in Tenascin C, Platelet-derived growth factor receptor, Neuroglia and Transplantation. His Integrin study combines topics in areas such as Laminin, Molecular biology, Signal transduction and Growth factor. His Remyelination study integrates concerns from other disciplines, such as Multiple sclerosis, Regeneration and CNS demyelination.

He most often published in these fields:

  • Cell biology (64.41%)
  • Neuroscience (31.08%)
  • Oligodendrocyte (32.88%)

What were the highlights of his more recent work (between 2013-2021)?

  • Cell biology (64.41%)
  • Myelin (16.67%)
  • Neuroscience (31.08%)

In recent papers he was focusing on the following fields of study:

Charles ffrench-Constant focuses on Cell biology, Myelin, Neuroscience, Oligodendrocyte and Remyelination. His studies in Cell biology integrate themes in fields like Retinitis pigmentosa and Induced pluripotent stem cell. His study looks at the relationship between Myelin and topics such as Immunology, which overlap with Radiation therapy and Cancer research.

His research in the fields of Central nervous system and Hippocampus overlaps with other disciplines such as White matter and Mechanism. The Oligodendrocyte study combines topics in areas such as Myelin sheath, Multiple sclerosis, Node of Ranvier, Transplantation and Cell polarity. His research investigates the connection between Neuroepithelial cell and topics such as Integrin that intersect with problems in Cellular differentiation.

Between 2013 and 2021, his most popular works were:

  • Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration (213 citations)
  • Regenerating CNS myelin - from mechanisms to experimental medicines. (200 citations)
  • Altered human oligodendrocyte heterogeneity in multiple sclerosis (189 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Genetics
  • Internal medicine

Charles ffrench-Constant mainly investigates Cell biology, Neuroscience, Myelin, Oligodendrocyte and Stem cell. Charles ffrench-Constant integrates Cell biology with Antigen processing in his study. His research integrates issues of Translational research, Clinical trial, Neurodegeneration and Gene expression profiling in his study of Neuroscience.

His Myelin study incorporates themes from Progenitor cell, Major histocompatibility complex and Experimental autoimmune encephalomyelitis. His studies deal with areas such as Myelin sheaths, Multiple sclerosis, Cognitive science and Developmental neurobiology as well as Oligodendrocyte. His Stem cell research includes elements of Embryonic stem cell and Adult stem cell.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Remyelination in the CNS: from biology to therapy

Robin J. M. Franklin;Charles ffrench-Constant.
Nature Reviews Neuroscience (2008)

1700 Citations

M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination

Veronique E. Miron;Amanda Boyd;Jing Wei Zhao;Tracy J. Yuen;Tracy J. Yuen.
Nature Neuroscience (2013)

1416 Citations

Evidence for specific cognitive deficits in preclinical Huntington's disease.

Andrew David Lawrence;J. R. Hodges;Anne Elizabeth Rosser;A. Kershaw.
Brain (1998)

540 Citations

Retinoid X receptor gamma signaling accelerates CNS remyelination

Jeffrey K Huang;Andrew A Jarjour;Brahim Nait Oumesmar;Christophe Kerninon.
Nature Neuroscience (2011)

483 Citations

The Chemokine Receptor CXCR2 Controls Positioning of Oligodendrocyte Precursors in Developing Spinal Cord by Arresting Their Migration

Hui Hsin Tsai;Emma Frost;Vivien To;Shenandoah Robinson.
Cell (2002)

466 Citations

Regenerating CNS myelin — from mechanisms to experimental medicines

Robin J M Franklin;Charles Ffrench-Constant.
Nature Reviews Neuroscience (2017)

430 Citations

Generation of an environmental niche for neural stem cell development by the extracellular matrix molecule tenascin C.

Emmanuel Garcion;Aida Halilagic;Andreas Faissner;Charles ffrench-Constant.
Development (2004)

389 Citations

Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration

Alexander Raven;Wei-Yu Lu;Tak Yung Man;Sofia Ferreira-Gonzalez.
Nature (2017)

356 Citations

Pathogenesis of multiple sclerosis.

C ffrench-Constant.
The Lancet (1994)

330 Citations

β1 integrins activate a MAPK signalling pathway in neural stem cells that contributes to their maintenance

Lia S. Campos;Dino P. Leone;Joao B. Relvas;Cord Brakebusch.
Development (2004)

330 Citations

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