His primary areas of investigation include Neuroscience, Retinal ganglion cell, Glaucoma, Optic nerve and Progenitor cell. His Neuroscience research is multidisciplinary, incorporating perspectives in Brain-derived neurotrophic factor and Developmental biology, Cell biology. His Glaucoma research is multidisciplinary, relying on both Retina, Intraocular pressure and Gene expression.
As part of one scientific family, Philip J. Horner deals mainly with the area of Optic nerve, narrowing it down to issues related to the Axon, and often Axoplasmic transport, Optic tract, Optic neuropathy and Superior colliculus. His study with Progenitor cell involves better knowledge in Stem cell. His work is dedicated to discovering how Stem cell, Adult stem cell are connected with GDF7, Transplantation and Neural stem cell and other disciplines.
His scientific interests lie mostly in Neuroscience, Glaucoma, Spinal cord, Pathology and Spinal cord injury. His Neuroscience research includes themes of Progenitor cell, Stem cell and Neural stem cell. The various areas that he examines in his Progenitor cell study include Immunology and Oligodendrocyte.
His research investigates the link between Glaucoma and topics such as Optic nerve that cross with problems in Axon and Retina. His research in Spinal cord intersects with topics in NMDA receptor and Stimulation. Philip J. Horner combines subjects such as Lesion and Myelin with his study of Spinal cord injury.
His primary areas of study are Neuroscience, Spinal cord, Neural stem cell, Central nervous system and Peptide. His Neuroscience study integrates concerns from other disciplines, such as Neurodegeneration and Stem cell. Philip J. Horner works in the field of Spinal cord, focusing on Spinal cord injury in particular.
His biological study spans a wide range of topics, including Neurogenesis, Cell, Cell type and Extracellular matrix. His study in Central nervous system is interdisciplinary in nature, drawing from both Spinal cord stimulation and Controlled release. His Retinal ganglion cell study in the realm of Retina connects with subjects such as Nerve Expansion.
Philip J. Horner spends much of his time researching Neuroscience, Polymer, Gene delivery, Neural stem cell and Peptide. Philip J. Horner is interested in Neuroprotection, which is a branch of Neuroscience. His Polymer research incorporates themes from Combinatorial chemistry, Nucleic acid, Polymer chemistry and Transfection.
While the research belongs to areas of Neural stem cell, Philip J. Horner spends his time largely on the problem of Choroid plexus, intersecting his research to questions surrounding Cell biology. His work carried out in the field of Cell biology brings together such families of science as Choroid Plexus Epithelium, Drug delivery to the brain and Pathology. His Peptide study deals with Intracellular intersecting with Biophysics.
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Regenerating the damaged central nervous system
Philip J. Horner;Fred H. Gage.
Nature (2000)
Proliferation and differentiation of progenitor cells throughout the intact adult rat spinal cord
Philip J. Horner;Ann E. Power;Gerd Kempermann;Gerd Kempermann;H. Georg Kuhn.
The Journal of Neuroscience (2000)
Adult Spinal Cord Stem Cells Generate Neurons after Transplantation in the Adult Dentate Gyrus
Lamya S. Shihabuddin;Philip J. Horner;Jasodhara Ray;Fred H. Gage.
The Journal of Neuroscience (2000)
Neurotrophin-3 and Brain-Derived Neurotrophic Factor Induce Oligodendrocyte Proliferation and Myelination of Regenerating Axons in the Contused Adult Rat Spinal Cord
Dana M. McTigue;Philip J. Horner;Bradford T. Stokes;Fred H. Gage.
The Journal of Neuroscience (1998)
Progressive Ganglion Cell Degeneration Precedes Neuronal Loss in a Mouse Model of Glaucoma
Brian P. Buckingham;Denise M. Inman;Wendi Lambert;Ericka Oglesby.
The Journal of Neuroscience (2008)
Distal axonopathy with structural persistence in glaucomatous neurodegeneration
Samuel D. Crish;Rebecca M. Sappington;Denise M. Inman;Philip J. Horner.
Proceedings of the National Academy of Sciences of the United States of America (2010)
Reduced retina microglial activation and improved optic nerve integrity with minocycline treatment in the DBA/2J mouse model of glaucoma.
Alejandra Bosco;Denise M. Inman;Michael R. Steele;Guangming Wu.
Investigative Ophthalmology & Visual Science (2008)
A Quantitative Spatial Analysis of the Blood–Spinal Cord Barrier: I. Permeability Changes after Experimental Spinal Contusion Injury
Phillip G. Popovich;Philip J. Horner;Bradford B. Mullin;Bradford T. Stokes.
Experimental Neurology (1996)
Fate of endogenous stem/progenitor cells following spinal cord injury.
Laura Lynn Horky;Francesco Galimi;Fred H. Gage;Philip J. Horner.
The Journal of Comparative Neurology (2006)
Retinal Ganglion Cells Downregulate Gene Expression and Lose Their Axons within the Optic Nerve Head in a Mouse Glaucoma Model
Ileana Soto;Ileana Soto;Ericka Oglesby;Brian P. Buckingham;Janice L. Son.
The Journal of Neuroscience (2008)
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