David J. Calkins

Overview

Best Publications

• Progressive Ganglion Cell Degeneration Precedes Neuronal Loss in a Mouse Model of Glaucoma

  Brian P. Buckingham;Denise M. Inman;Wendi Lambert;Ericka Oglesby

  463
  Citations

• The microbead occlusion model: a paradigm for induced ocular hypertension in rats and mice

  Rebecca M. Sappington;Brian J. Carlson;Samuel D. Crish;David J. Calkins

  444
  Citations

• Distal axonopathy with structural persistence in glaucomatous neurodegeneration

  Samuel D. Crish;Rebecca M. Sappington;Denise M. Inman;Philip J. Horner

  389
  Citations

• Reduced retina microglial activation and improved optic nerve integrity with minocycline treatment in the DBA/2J mouse model of glaucoma.

  Alejandra Bosco;Denise M. Inman;Michael R. Steele;Guangming Wu

  370
  Citations

• Solving neurodegeneration: common mechanisms and strategies for new treatments

  Unknown

  357
  Citations

• Critical pathogenic events underlying progression of neurodegeneration in glaucoma.

  David J. Calkins

  344
  Citations

• Microcircuitry and Mosaic of a Blue–Yellow Ganglion Cell in the Primate Retina

  David J. Calkins;Yoshihiko Tsukamoto;Peter Sterling

  270
  Citations

• Induced Autoimmunity to Heat Shock Proteins Elicits Glaucomatous Loss of Retinal Ganglion Cell Neurons via Activated T-Cell-Derived Fas-Ligand

  Martin B. Wax;Gülgün Tezel;Junjie Yang;Guanghua Peng

  252
  Citations

• Seeing with S cones.

  David J. Calkins

  244
  Citations

• Microarray analysis of retinal gene expression in the DBA/2J model of glaucoma.

  Michael R. Steele;Denise M. Inman;David J. Calkins;Philip J. Horner

  241
  Citations

• M and L cones in macaque fovea connect to midget ganglion cells by different numbers of excitatory synapses.

  David J. Calkins;Stanley J. Schein;Yoshihiko Tsukamoto;Peter Sterling

  237
  Citations

• TRPV1: contribution to retinal ganglion cell apoptosis and increased intracellular Ca2+ with exposure to hydrostatic pressure.

  Rebecca M. Sappington;Tatiana Sidorova;Daniel J. Long;David J. Calkins

  236
  Citations

• Optic Neuropathy Due to Microbead-Induced Elevated Intraocular Pressure in the Mouse

  Huihui Chen;Xin Wei;Xin Wei;Kin-Sang Cho;Guochun Chen;Guochun Chen

  215
  Citations

• Bilateral visual improvement with unilateral gene therapy injection for Leber hereditary optic neuropathy

  Patrick Yu-Wai-Man;Nancy J. Newman;Valerio Carelli;Mark L. Moster

  210
  Citations

• Light Scattering from Intact Cells Reports Oxidative-Stress-Induced Mitochondrial Swelling

  Jeremy D. Wilson;Chad E. Bigelow;David J. Calkins;Thomas H. Foster

  201
  Citations

• Interleukin-6 protects retinal ganglion cells from pressure-induced death.

  Rebecca M Sappington;Matilda Chan;David J Calkins

  187
  Citations

• Neurodegeneration in Glaucoma: Progression and Calcium-Dependent Intracellular Mechanisms

  Samuel D. Crish;David J. Calkins

  175
  Citations

• Contribution of TRPV1 to Microglia-Derived IL-6 and NFκB Translocation with Elevated Hydrostatic Pressure

  Rebecca M. Sappington;David J. Calkins

  168
  Citations

• Metabolic vulnerability disposes retinal ganglion cell axons to dysfunction in a model of glaucomatous degeneration

  Selva Baltan;Denise M. Inman;Camelia A. Danilov;Richard S. Morrison

  159
  Citations

• TRPV1: a stress response protein in the central nervous system.

  Karen W Ho;Nicholas J Ward;David J Calkins

  151
  Citations

• Evidence that Circuits for Spatial and Color Vision Segregate at the First Retinal Synapse

  David J Calkins;Peter Sterling

  145
  Citations