World's Best Scientists 2026 revealed!
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Best Female Scientists
2025

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Best Female Scientists

D-Index
110
Citations
54082
World Ranking
879
National Ranking
533

Neuroscience

D-Index
114
Citations
58536
World Ranking
462
National Ranking
268

Research.com Recognitions

  • 2025 - Research.com Best Female Scientists Award
  • 2005 - Fellow of Alfred P. Sloan Foundation

Overview

Guo Li Ming is affiliated with the University of Pennsylvania in the United States. Their research spans a multidisciplinary range across biochemistry, genetics, molecular biology, neuroscience, and medicine, evidencing a focus on molecular and cellular mechanisms underlying neural development and pathology.

The primary fields of study Guo Li Ming engages with include:

  • Biochemistry, Genetics and Molecular Biology
  • Neuroscience
  • Medicine

Their work extends into important subfields such as:

  • Molecular Biology
  • Cellular and Molecular Neuroscience
  • Developmental Neuroscience
  • Genetics
  • Cognitive Neuroscience

Key research topics covered by Guo Li Ming encompass:

  • Neurogenesis and neuroplasticity mechanisms
  • Pluripotent Stem Cells Research
  • RNA modifications and cancer
  • Epigenetics and DNA Methylation
  • CAR-T cell therapy research
  • Genetics and Neurodevelopmental Disorders
  • Neuroscience and Neural Engineering

Their publication record includes papers in prominent scientific journals. Recent papers authored or coauthored include:

  • "Sliced Human Cortical Organoids for Modeling Distinct Cortical Layer Formation," 2020, Cell Stem Cell
  • "Human Pluripotent Stem Cell-Derived Neural Cells and Brain Organoids Reveal SARS-CoV-2 Neurotropism Predominates in Choroid Plexus Epithelium," 2020, Cell Stem Cell
  • "Molecular landscapes of human hippocampal immature neurons across lifespan," 2022, Nature
  • "Intrathecal bivalent CAR T cells targeting EGFR and IL13Rα2 in recurrent glioblastoma: phase 1 trial interim results," 2024, Nature Medicine
  • "A nomenclature consensus for nervous system organoids and assembloids," 2022, Nature

Guo Li Ming has published extensively in various venues, frequently contributing to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Stem Cell
  • Neuro-Oncology
  • Nature
  • UNC Libraries

The scientist has collaborated often with the following frequent co-authors:

  • Hongjun Song
  • Kimberly M. Christian
  • Yusha Sun
  • Yijing Su
  • Feng Zhang

Guo Li Ming was recognized with a fellowship from the Alfred P. Sloan Foundation in 2005.

Best Publications

  • Adult neurogenesis in the mammalian brain: significant answers and significant questions.

    Guo li Ming;Hongjun Song

  • ADULT NEUROGENESIS IN THE MAMMALIAN CENTRAL NERVOUS SYSTEM

    Guo Li Ming;Hongjun Song

  • Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure

    Xuyu Qian;Ha Nam Nguyen;Mingxi M. Song;Christopher Hadiono

  • Distinct Morphological Stages of Dentate Granule Neuron Maturation in the Adult Mouse Hippocampus

    Chunmei Zhao;E. Matthew Teng;Robert G. Summers;Guo Li Ming

  • Hydroxylation of 5-Methylcytosine by TET1 Promotes Active DNA Demethylation in the Adult Brain

    Junjie U. Guo;Yijing Su;Chun Zhong;Guo Li Ming

  • GABA regulates synaptic integration of newly generated neurons in the adult brain

    Shaoyu Ge;Eyleen L K Goh;Kurt A. Sailor;Yasuji Kitabatake

  • Zika Virus Infects Human Cortical Neural Progenitors and Attenuates Their Growth

    Hengli Tang;Christy Hammack;Sarah C. Ogden;Zhexing Wen

  • Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates.

    Luca Tamagnone;Stefania Artigiani;Hang Chen;Zhigang He

  • A Critical Period for Enhanced Synaptic Plasticity in Newly Generated Neurons of the Adult Brain

    Shaoyu Ge;Chih hao Yang;Chih hao Yang;Kuei sen Hsu;Guo li Ming

  • Conversion of neuronal growth cone responses from repulsion to attraction by cyclic nucleotides.

    Hong Jun Song;Guo Li Ming;Zhigang He;Maxime Lehmann

  • Neuronal Activity–Induced Gadd45b Promotes Epigenetic DNA Demethylation and Adult Neurogenesis

    Dengke K. Ma;Mi Hyeon Jang;Junjie U. Guo;Yasuji Kitabatake

  • A Patient-Derived Glioblastoma Organoid Model and Biobank Recapitulates Inter- and Intra-tumoral Heterogeneity

    Fadi Jacob;Fadi Jacob;Ryan D. Salinas;Daniel Y. Zhang;Phuong T.T. Nguyen

  • In vivo clonal analysis reveals self-renewing and multipotent adult neural stem cell characteristics.

    Michael A. Bonaguidi;Michael A. Wheeler;Jason S. Shapiro;Ryan P. Stadel

  • Single-Cell RNA-Seq with Waterfall Reveals Molecular Cascades underlying Adult Neurogenesis.

    Jaehoon Shin;Daniel A. Berg;Yunhua Zhu;Joseph Y. Shin

  • Adult Mammalian Neural Stem Cells and Neurogenesis: Five Decades Later

    Allison M. Bond;Guo Li Ming;Hongjun Song

  • Neurogenesis in the Adult Brain: New Strategies for Central Nervous System Diseases

    D. Chichung Lie;Hongjun Song;Sophia A. Colamarino;Guo Li Ming

  • cAMP-induced switching in turning direction of nerve growth cones

    Hong Jun Song;Guo Li Ming;Mu Ming Poo

  • Distribution, recognition and regulation of non-CpG methylation in the adult mammalian brain

    Junjie U. Guo;Yijing Su;Joo Heon Shin;Jaehoon Shin

  • cAMP-Dependent Growth Cone Guidance by Netrin-1

    Guo Li Ming;Hong Jun Song;Benedikt Berninger;Christine E. Holt

  • Temporal Control of Mammalian Cortical Neurogenesis by m6A Methylation

    Ki Jun Yoon;Francisca Rojas Ringeling;Caroline Vissers;Fadi Jacob

  • Disrupted-In-Schizophrenia 1 regulates integration of newly generated neurons in the adult brain

    Xin Duan;Jay H. Chang;Shaoyu Ge;Regina L. Faulkner

Frequent Co-Authors

Hongjun Song
Hongjun Song University of Pennsylvania
Kimberly M. Christian
Kimberly M. Christian University of Pennsylvania
Nicolas Toni
Nicolas Toni University of Lausanne
Mu-ming Poo
Mu-ming Poo Chinese Academy of Sciences
Peng Jin
Peng Jin Emory University
Marc Tessier-Lavigne
Marc Tessier-Lavigne Xaira Therapeutics
John A. Wolf
John A. Wolf University of Pennsylvania
Kuei Sen Hsu
Kuei Sen Hsu National Cheng Kung University
Zhigang He
Zhigang He Boston Children's Hospital
Fred H. Gage
Fred H. Gage Salk Institute for Biological Studies

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