World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
103
Citations
42531
World Ranking
1308
National Ranking
765

Overview

James J. Lah is affiliated with Emory University in the United States. Their research primarily focuses on Alzheimer's disease and related neurodegenerative disorders, engaging deeply with the molecular and physiological underpinnings of these conditions.

The scientist has contributed extensively to the field of medicine, with 225 publications categorized under this field. Their work spans several subfields including physiology, molecular biology, psychiatry and mental health, neurology, and aspects of health, toxicology, and mutagenesis.

Key topics within their research portfolio include:

  • Alzheimer's disease research and treatments
  • Dementia and cognitive impairment research
  • Bioinformatics and genomic networks
  • Metabolomics and mass spectrometry studies
  • Tryptophan and brain disorders
  • Air quality and health impacts
  • Advanced proteomics techniques and applications

James J. Lah has collaborated frequently with several researchers, including Allan I. Levey, Nicholas T. Seyfried, Eric B. Dammer, Duc M. Duong, and Thomas S. Wingo. These collaborations have contributed to a significant body of work published in diverse scientific venues.

Their publications have appeared in a variety of journals and platforms, with notable publication venues including:

  • Alzheimer s & Dementia
  • bioRxiv (Cold Spring Harbor Laboratory)
  • arXiv (Cornell University)
  • Molecular Neurodegeneration
  • Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition

A selection of recent papers authored or co-authored by James J. Lah includes:

  • Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation, 2020, Nature Medicine
  • Large-scale deep multi-layer analysis of Alzheimer's disease brain reveals strong proteomic disease-related changes not observed at the RNA level, 2022, Nature Neuroscience
  • Integrated proteomics reveals brain-based cerebrospinal fluid biomarkers in asymptomatic and symptomatic Alzheimer's disease, 2020, Science Advances
  • Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer's disease pathogenesis, 2021, Nature Genetics
  • A trial of gantenerumab or solanezumab in dominantly inherited Alzheimer's disease, 2021, Nature Medicine

Best Publications

  • Variant of TREM2 associated with the risk of Alzheimer's disease

    Thorlakur Jonsson;Hreinn Stefansson;Stacy Steinberg;Ingileif Jonsdottir

  • Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.

    Adam C. Naj;Gyungah Jun;Gary W. Beecham;Li-San Wang

  • Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis

    Y. Iturria-Medina;R. C. Sotero;P. J. Toussaint;J. M. Mateos-Pérez

  • Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

    Rebecca Sims;Sven J. Van Der Lee;Adam C. Naj;Céline Bellenguez;Céline Bellenguez

  • Large-scale proteomic analysis of Alzheimer’s disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation

    Erik C.B. Johnson;Eric B. Dammer;Duc M. Duong;Lingyan Ping

  • Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions

    Vivianna M. Van Deerlin;Patrick M A Sleiman;Maria Martinez-Lage;Maria Martinez-Lage;Alice Chen-Plotkin

  • The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease.

    Minghui Wang;Noam D. Beckmann;Panos Roussos;Erming Wang

  • Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study

    Eric M Reiman;Joseph F Arboleda-Velasquez;Yakeel T Quiroz;Matthew J Huentelman

  • A Multi-network Approach Identifies Protein-Specific Co-expression in Asymptomatic and Symptomatic Alzheimer’s Disease

    Nicholas T. Seyfried;Eric B. Dammer;Vivek Swarup;Divya Nandakumar

  • Evidence for brain glucose dysregulation in Alzheimer's disease

    Yang An;Vijay R. Varma;Sudhir Varma;Ramon Casanova

  • Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis

    David C. Whitcomb;Jessica LaRusch;Alyssa M. Krasinskas;Lambertus Klei

  • Loss of apolipoprotein E receptor LR11 in Alzheimer disease.

    Clemens R. Scherzer;Katrin Offe;Marla Gearing;Howard D. Rees

  • Loss-of-function variants in ABCA7 confer risk of Alzheimer's disease

    Stacy Steinberg;Hreinn Stefansson;Thorlakur Jonsson;Hrefna Johannsdottir

  • Proteomic characterization of postmortem amyloid plaques isolated by laser capture microdissection

    Lujian Liao;Dongmei Cheng;Jian Wang;Duc M. Duong

  • The lipoprotein receptor LR11 regulates amyloid beta production and amyloid precursor protein traffic in endosomal compartments.

    Katrin Offe;Sara E. Dodson;James T. Shoemaker;Jason J. Fritz

  • A selective allosteric potentiator of the M1 muscarinic acetylcholine receptor increases activity of medial prefrontal cortical neurons and restores impairments in reversal learning.

    J. K. Shirey;A. E. Brady;P. J. Jones;A. A. Davis

  • Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions.

    S K Sieberts;T M Perumal;M M Carrasquillo;M Allen

  • Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer's disease.

    Srikant Rangaraju;Eric B. Dammer;Syed Ali Raza;Priyadharshini Rathakrishnan

  • A novel Alzheimer disease locus located near the gene encoding tau protein

    G. Jun;C. A. Ibrahim-Verbaas;M. Vronskaya;J-C Lambert;J-C Lambert;J-C Lambert

  • U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease.

    Bing Bai;Chadwick M. Hales;Ping Chung Chen;Yair Gozal

Frequent Co-Authors

Allan I. Levey
Allan I. Levey Emory University
Nicholas T. Seyfried
Nicholas T. Seyfried Emory University
Duc M. Duong
Duc M. Duong Emory University
Eric B. Dammer
Eric B. Dammer Emory University
Marla Gearing
Marla Gearing Emory University
Juan C. Troncoso
Juan C. Troncoso Johns Hopkins University School of Medicine
Felicia C. Goldstein
Felicia C. Goldstein Emory University
David A. Bennett
David A. Bennett Rush University Medical Center
Philip L. De Jager
Philip L. De Jager Columbia University
John C. Morris
John C. Morris Washington University in St. Louis

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Biology and Biochemistry can open doors to a variety of in-demand careers in healthcare and science. Many students now opt for flexible education models, such as online learning, to gain the credentials they need. For those interested in combining scientific knowledge with business skills, pursuing an affordable online MBA in healthcare management is a great option. This pathway offers advanced leadership opportunities and broadens career possibilities within the healthcare sector.

Another popular career direction is medical coding and billing. Understanding the differences between certifications, such as cpc vs ccs, is crucial for those aiming to specialize in this field. Certification impacts both job prospects and salary potential.

Students often ask, what is medical coding salary? Earnings vary but tend to be competitive, especially as demand for qualified professionals grows. But is is medical billing and coding in demand? The answer is yes, with solid job outlooks and diverse workplace settings available for skilled graduates. Whether you prefer management, laboratory, or administrative roles, online degrees provide flexible pathways to a rewarding science-based career.

Best Scientists Citing James J. Lah

Trending Scientists