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Christopher J. Rhodes

Christopher J. Rhodes

D-Index & Metrics

Medicine

D-Index
104
Citations
40349
World Ranking
7045
National Ranking
3705

Overview

Christopher J. Rhodes is affiliated with the University of Chicago in the United States. Their research activity spans multiple fields within medicine, particularly with a focus on pulmonary and respiratory medicine, molecular biology, cancer research, cardiology and cardiovascular medicine, and genetics.

The primary areas of study include pulmonary hypertension research and treatments, cancer-related molecular mechanisms research, RNA modifications and cancer, microRNA in disease regulation, circular RNAs in diseases, vascular anomalies and treatments, as well as medical imaging and pathology studies.

The scholar has published extensively, with notable venues including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • European Respiratory Journal
  • American Journal of Respiratory and Critical Care Medicine
  • Nature Communications
  • Circulation

Frequent co-authors involve collaboration with:

  • Martin R. Wilkins
  • Stefan Gräf
  • Luke Howard
  • Nicholas W. Morrell
  • Allan Lawrie

Recent papers authored or co-authored include:

  • Whole-Blood RNA Profiles Associated with Pulmonary Arterial Hypertension and Clinical Outcome, 2020, American Journal of Respiratory and Critical Care Medicine
  • A diagnostic miRNA signature for pulmonary arterial hypertension using a consensus machine learning approach, 2021, EBioMedicine
  • Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension, 2020, Nature Communications
  • Mendelian randomisation and experimental medicine approaches to interleukin-6 as a drug target in pulmonary arterial hypertension, 2021, European Respiratory Journal
  • Rare variant analysis of 4241 pulmonary arterial hypertension cases from an international consortium implicates FBLN2, PDGFD, and rare de novo variants in PAH, 2021, Genome Medicine

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Type 2 Diabetes-a Matter of ß-Cell Life and Death?

    Christopher J. Rhodes

  • β-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment

    Philippe A. Halban;Kenneth S. Polonsky;Donald W. Bowden;Meredith A. Hawkins

  • Regulation of Endothelial Constitutive Nitric Oxide Synthase Gene Expression in Endothelial Cells and In Vivo A Specific Vascular Action of Insulin

    Koji Kuboki;Zhen Y. Jiang;Noriko Takahara;Sung Woo Ha

  • An 18-kDa Translocator Protein (TSPO) polymorphism explains differences in binding affinity of the PET radioligand PBR28

    David R Owen;Astrid J Yeo;Roger N Gunn;Roger N Gunn;Roger N Gunn;Kijoung Song

  • Intracellular signalling. Key enzyme in leptin-induced anorexia.

    Kevin D. Niswender;Gregory J. Morton;Walter H. Stearns;Christopher J. Rhodes

  • The Hyperglycemia-induced Inflammatory Response in Adipocytes THE ROLE OF REACTIVE OXYGEN SPECIES

    Ying Lin;Anders H. Berg;Puneeth Iyengar;Tony K.T. Lam

  • Glucose or diabetes activates p38 mitogen-activated protein kinase via different pathways

    Masahiko Igarashi;Hisao Wakasaki;Noriko Takahara;Hidehiro Ishii

  • Leptin Acts via Leptin Receptor-Expressing Lateral Hypothalamic Neurons to Modulate the Mesolimbic Dopamine System and Suppress Feeding

    Gina M. Leinninger;Young Hwan Jo;Rebecca L. Leshan;Gwendolyn W. Louis

  • Glucagon-like peptide-1 prevents beta cell glucolipotoxicity.

    J. Buteau;W. El-Assaad;C. J. Rhodes;L. Rosenberg

  • Induction Of Endothelin‐1 Expression By Glucose: An Effect Of Protein Kinase C Activation

    Jy Park;N Takahara;A Gabriele;E Chou

  • Leptin action via neurotensin neurons controls orexin, the mesolimbic dopamine system and energy balance

    Gina M. Leinninger;Darren M. Opland;Young Hwan Jo;Miro Faouzi

  • Chronic exposure to free fatty acid reduces pancreatic beta cell insulin content by increasing basal insulin secretion that is not compensated for by a corresponding increase in proinsulin biosynthesis translation.

    L C Bollheimer;R H Skelly;M W Chester;J D McGarry

  • Insulin-like growth factor I (IGF-I)-stimulated pancreatic beta-cell growth is glucose-dependent. Synergistic activation of insulin receptor substrate-mediated signal transduction pathways by glucose and IGF-I in INS-1 cells.

    Sigrun R. Hügl;Morris F. White;Christopher J. Rhodes

  • Formation of a Human β-Cell Population within Pancreatic Islets Is Set Early in Life

    Brigid E. Gregg;Patrick C. Moore;Damien Demozay;Ben A. Hall

  • Leptin regulates insulin sensitivity via phosphatidylinositol-3-OH kinase signaling in mediobasal hypothalamic neurons

    Gregory J. Morton;Richard W. Gelling;Kevin D. Niswender;Christopher D. Morrison

  • Protein Kinase B/Akt Prevents Fatty Acid-induced Apoptosis in Pancreatic β-Cells (INS-1)

    Christian E. Wrede;Lorna M. Dickson;Melissa K. Lingohr;Isabelle Briaud

  • Identification of rare sequence variation underlying heritable pulmonary arterial hypertension.

    Stefan Gräf;Matthias Haimel;Marta Bleda;Charaka Hadinnapola

  • Protein Kinase Cζ Activation Mediates Glucagon-Like Peptide-1–Induced Pancreatic β-Cell Proliferation

    Jean Buteau;Sylvain Foisy;Christopher J. Rhodes;Lee Carpenter

  • b-Cell Failure in Type 2 Diabetes: Postulated Mechanisms and Prospects for Prevention and

    Universityof Geneva;Philippe A. Halban;Kenneth S. Polonsky;Donald W. Bowden

Frequent Co-Authors

Martin G. Myers
Martin G. Myers University of Toronto
Philippe A. Halban
Philippe A. Halban University of Geneva
Marc Prentki
Marc Prentki University of Montreal
Michael W. Schwartz
Michael W. Schwartz University of Washington
Mark A. Atkinson
Mark A. Atkinson University of Florida
Louis H. Philipson
Louis H. Philipson University of Chicago
Barbara E. Corkey
Barbara E. Corkey Boston University
George L. King
George L. King Harvard University
Morris F. White
Morris F. White Boston Children's Hospital
Per-Olof Berggren
Per-Olof Berggren Karolinska Institute

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