His primary areas of investigation include Neuroscience, Genetics, Transcriptome, Human brain and Astrocyte. His research in Neuroscience intersects with topics in Neurotrophic factors and Anatomy. The concepts of his Genetics study are interwoven with issues in Frontotemporal lobar degeneration, Disease and Basal ganglia calcification.
He has researched Transcriptome in several fields, including Downregulation and upregulation and Gene expression profiling. His studies deal with areas such as Biomarker, FOXP2, Prefrontal cortex and Cerebral organoid as well as Human brain. Giovanni Coppola usually deals with Astrocyte and limits it to topics linked to GCaMP and Biological neural network, Glutamate receptor, In vivo and Proteomics.
Giovanni Coppola mainly focuses on Neuroscience, Genetics, Frontotemporal dementia, Internal medicine and Disease. The concepts of his Neuroscience study are interwoven with issues in Neurodegeneration and Regeneration. Gene, Copy-number variation, Genome-wide association study, Allele and Spinocerebellar ataxia are the primary areas of interest in his Genetics study.
His is doing research in C9orf72 and Frontotemporal lobar degeneration, both of which are found in Frontotemporal dementia. His research in Internal medicine intersects with topics in Endocrinology and Oncology. A large part of his Disease studies is devoted to Alzheimer's disease.
His scientific interests lie mostly in Frontotemporal dementia, Neuroscience, Gene, C9orf72 and Genetics. He has included themes like Neurodegeneration and Atrophy in his Frontotemporal dementia study. His biological study spans a wide range of topics, including Receptor and Downregulation and upregulation.
The various areas that he examines in his Gene study include Cell type and Tourette syndrome. His C9orf72 research includes themes of Genetic screen, Pediatrics and Neuropsychology. Giovanni Coppola regularly ties together related areas like PSEN1 in his Genetics studies.
Giovanni Coppola mainly investigates Frontotemporal dementia, C9orf72, Neuroscience, Frontotemporal lobar degeneration and Gene. The study incorporates disciplines such as Pathological and Atrophy in addition to Frontotemporal dementia. He combines subjects such as Symptom onset, Tau protein and Neurodegeneration with his study of C9orf72.
His Neurodegeneration research is multidisciplinary, relying on both Cell biology and Trinucleotide repeat expansion. Neuroscience and Receptor are frequently intertwined in his study. His study looks at the intersection of TARDBP and topics like TREM2 with Genetics.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS
Mariely DeJesus-Hernandez;Ian R. Mackenzie;Bradley F. Boeve;Adam L. Boxer.
Neuron (2011)
Astrocyte scar formation aids central nervous system axon regeneration
Mark A. Anderson;Joshua E. Burda;Yilong Ren;Yan Ao.
Nature (2016)
Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease
Alan H Nagahara;David A Merrill;Giovanni Coppola;Shingo Tsukada.
Nature Medicine (2009)
Identification of common variants associated with human hippocampal and intracranial volumes
Jason L Stein;Sarah E Medland;Sarah E Medland;Alejandro Arias Vasquez;Alejandro Arias Vasquez;Derrek P Hibar.
Nature Genetics (2012)
Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders
Phil H. Lee;Verneri Anttila;Hyejung Won;Yen-Chen A. Feng.
Cell (2019)
Functional and Evolutionary Insights into Human Brain Development through Global Transcriptome Analysis
Matthew B. Johnson;Yuka Imamura Kawasawa;Christopher E. Mason;Željka Krsnik.
Neuron (2009)
The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data
Paul M. Thompson;Jason L. Stein;Sarah E. Medland;Derrek P. Hibar.
Brain Imaging and Behavior (2014)
Human-specific transcriptional regulation of CNS development genes by FOXP2
Genevieve Konopka;Jamee M. Bomar;Kellen D. Winden;Giovanni Coppola.
Nature (2009)
Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation.
Hansen Lui;Jiasheng Zhang;Stefanie R. Makinson;Michelle K. Cahill.
Cell (2016)
Neural Circuit-Specialized Astrocytes: Transcriptomic, Proteomic, Morphological, and Functional Evidence
Hua Chai;Blanca Diaz-Castro;Eiji Shigetomi;Emma Monte.
Neuron (2017)
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