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Chemistry

D-Index
71
Citations
16378
World Ranking
5620
National Ranking
1736

Overview

Michael R. Kilbourn is affiliated with the University of Michigan-Ann Arbor in the United States. Their research primarily focuses on the intersection of medicine, biochemistry, genetics, and molecular biology, with particular emphasis on radiology, nuclear medicine, and imaging.

The scientist has contributed extensively to in vivo medical imaging techniques and radiopharmaceutical chemistry, with a notable focus on neuroscience and neuropharmacology research. Their work also spans biotin-related studies, receptor mechanisms and signaling, and advanced MRI techniques.

Frequent coauthors in Kilbourn's research include Peter J. H. Scott, Allen F. Brooks, Alexandra Sowa, Xia Shao, and Tanpreet Kaur. These collaboration patterns suggest active engagement in interdisciplinary and team-based research efforts.

Publications by Michael R. Kilbourn have appeared in established venues such as ACS Chemical Neuroscience, Nuclear Medicine and Biology, EJNMMI Radiopharmacy and Chemistry, Biomedicines, and ACS Medicinal Chemistry Letters. The distribution of publications highlights a consistent presence in journals specializing in chemical neuroscience and nuclear medicine.

Representative recent papers include:

  • Use of 55 PET radiotracers under approval of a Radioactive Drug Research Committee (RDRC), 2020, EJNMMI Radiopharmacy and Chemistry
  • 11C- and 18F-Radiotracers for In Vivo Imaging of the Dopamine System: Past, Present and Future, 2021, Biomedicines
  • Classics in Neuroimaging: Development of Positron Emission Tomography Tracers for Imaging the GABAergic Pathway, 2020, ACS Chemical Neuroscience
  • Classics in Neuroimaging: Shedding Light on Opioid Receptors with Positron Emission Tomography Imaging, 2020, ACS Chemical Neuroscience
  • Classics in Neuroimaging: Imaging the Cholinergic System with Positron Emission Tomography, 2021, ACS Chemical Neuroscience

Their work addresses major topics such as medical imaging techniques and applications, radiopharmaceutical chemistry, neuroscience and neuropharmacology, and lung cancer treatments and mutations, illustrating a broad application of molecular and cellular biology methodologies.

Best Publications

  • A quantitative model for the in vivo assessment of drug binding sites with positron emission tomography.

    Mark A. Mintun;Marcus E. Raichle;Michael R. Kilbourn;G. Frederick Wooten

  • Regional mu opioid receptor regulation of sensory and affective dimensions of pain.

    Jon-Kar Zubieta;Yolanda R. Smith;Joshua A. Bueller;Yanjun Xu

  • Preclinical Properties of 18F-AV-45: A PET Agent for Aβ Plaques in the Brain

    Seok Rye Choi;Geoff Golding;Zhiping Zhuang;Wei Zhang

  • μ-Opioid Receptor-Mediated Antinociceptive Responses Differ in Men and Women

    Jon Kar Zubieta;Yolanda R. Smith;Joshua A. Bueller;Yanjun Xu

  • Compartmental Analysis of [11C]Flumazenil Kinetics for the Estimation of Ligand Transport Rate and Receptor Distribution Using Positron Emission Tomography

    R. A. Koeppe;V. A. Holthoff;K. A. Frey;K. A. Frey;M. R. Kilbourn

  • Relationship between lipophilicity and brain extraction of C-11-labeled radiopharmaceuticals.

    Douglas D. Dischino;Michael J. Welch;Michael R. Kilbourn;Marcus E. Raichle

  • Presynaptic monoaminergic vesicles in Parkinson's disease and normal aging

    Kirk A. Frey;Robert A. Koeppe;Michael R. Kilbourn;Thierry M. Vander Borght

  • Effects of Buprenorphine Maintenance Dose on μ -Opioid Receptor Availability, Plasma Concentrations, and Antagonist Blockade in Heroin-Dependent Volunteers

    Mark K. Greenwald;Chris Ellyn Johanson;David E. Moody;James H. Woods

  • Preparation of four fluorine- 18-labeled estrogens and their selective uptakes in target tissues of immature rats.

    Dale O. Kiesewetter;Michael R. Kilbourn;Scott W. Landvatter;Daniel F. Heiman

  • Cognitive function and nigrostriatal markers in abstinent methamphetamine abusers

    Chris Ellyn Johanson;Kirk A. Frey;Leslie H. Lundahl;Pamela Keenan

  • Positron Emission Tomographic Measurement of Cerebral Blood Flow and Permeability—Surface Area Product of Water Using [15O]Water and [11C]Butanol

    Peter Herscovitch;Marcus E. Raichle;Michael R. Kilbourn;Michael J. Welch

  • Aryltrimethylammonium trifluoromethanesulfonates as precursors to aryl [18F]fluorides: Improved synthesis of [18F]GBR‐13119

    Michael S. Haka;Michael R. Kilbourn;G. Leonard Watkins;Steven A. Toorongian

  • The vesicular monoamine transporter is not regulated by dopaminergic drug treatments.

    Thierry Vander Borght;Michael Kilbourn;Timothy Desmond;David Kuhl

  • Routine production of 2-deoxy-2-[18F]fluoro-D-glucose by direct nucleophilic exchange on a quaternary 4-aminopyridinium resin.

    Steven A. Toorongian;G.Keith Mulholland;Douglas M. Jewett;Michael A. Bachelor

  • Increased ventral striatal monoaminergic innervation in Tourette syndrome.

    Roger L. Albin;R. A. Koeppe;N. I. Bohnen;T. E. Nichols

  • Strategies for in vivo measurement of receptor binding using positron emission tomography.

    Joel S. Perlmutter;Kenneth B. Larson;Marcus E. Raichle;Joanne Markham

  • Synthesis and biodistribution of 18F-labeled fluoronitroimidazoles: potential in vivo markers of hypoxic tissue.

    Paul A. Jerabek;Timothy B. Patrick;Michael R. Kilbourn;Douglas D. Dischino

  • Buprenorphine-Induced Changes in Mu-Opioid Receptor Availability in Male Heroin-Dependent Volunteers: A Preliminary Study

    Jon Kar Zubieta;Mark K. Greenwald;Umberto Lombardi;James H. Woods

  • Fluorine-18 Labeling of Proteins

    Michael R. Kilbourn;Carmen S. Dence;Michael J. Welch;Carla J. Mathias

  • A simple 18O water target for 18F production.

    Michael R. Kilbourn;John T. Hood;Michael J. Welch

  • Kinetic Modeling of N-[11C]Methylpiperidin-4-yl Propionate: Alternatives for Analysis of an Irreversible Positron Emission Tomography Tracer for Measurement of Acetylcholinesterase Activity in Human Brain:

    Robert A. Koeppe;Kirk A. Frey;Scott E. Snyder;Phillipp Meyer

  • The vesicular monoamine transporter is not regulated by dopaminergic drug treatment.

    Thierry Vander Borght;M.R. Kilbourn;T.J. Desmond;D.E. Kuhl

Frequent Co-Authors

Kirk A. Frey
Kirk A. Frey University of Michigan–Ann Arbor
Robert A. Koeppe
Robert A. Koeppe University of Michigan–Ann Arbor
Michael J. Welch
Michael J. Welch Washington University in St. Louis
David E. Kuhl
David E. Kuhl University of Michigan–Ann Arbor
Roger L. Albin
Roger L. Albin University of Michigan–Ann Arbor
John A. Katzenellenbogen
John A. Katzenellenbogen University of Illinois at Urbana-Champaign
Satoshi Minoshima
Satoshi Minoshima University of Utah
Marcus E. Raichle
Marcus E. Raichle Washington University in St. Louis
Nicolaas I. Bohnen
Nicolaas I. Bohnen University of Michigan–Ann Arbor
James H. Woods
James H. Woods University of Michigan–Ann Arbor

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