World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
79
Citations
26115
World Ranking
17455
National Ranking
8740

Research.com Recognitions

  • 2011 - Japan Prize for contributions in the area of "Technological integration of medical science and engineering". Specifically, tomographic imaging in nuclear medicine.
  • 1989 - Member of the National Academy of Medicine (NAM)
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

David E. Kuhl is affiliated with the University of Michigan-Ann Arbor in the United States. Their research spans multiple areas within biochemistry, genetics, molecular biology, and medicine, with a significant focus on cell biology and molecular biology.

Their recent published works cover a range of topics related to cellular function and disease mechanisms. These include:

  • "Converging roles of PSENEN/PEN2 and CLN3 in the autophagy-lysosome system" (2021) published in Autophagy
  • "Neuronal activity regulates alternative exon usage" (2020) published in Molecular Brain
  • "The adaptor protein PICK1 targets the sorting receptor SorLA" (2022) published in Molecular Brain
  • "Dynamic regulation of integrin β1 phosphorylation supports invasion of breast cancer cells" (2025) published in Nature Cell Biology
  • "The insertion of Neomycin cassette impairs maternal and social behaviors in Arc/Arg3.1 knock-out mice" (2025) published in arXiv (Cornell University)

They collaborate frequently with other researchers in their field, notably:

  • Guido Hermey
  • Marcel Klein
  • Lars Binkle
  • Abuzar Kaleem
  • Sandra Oetjen

The scientist regularly publishes in certain venues, particularly:

  • Molecular Brain
  • Autophagy
  • Nature Cell Biology
  • arXiv (Cornell University)

David E. Kuhl's main fields of study are:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Their work also covers several specific subfields, including:

  • Cell Biology
  • Molecular Biology
  • Physiology
  • Epidemiology
  • Cancer Research

The scientist's research topics address key areas such as:

  • Cellular transport and secretion
  • Lysosomal Storage Disorders Research
  • Autophagy in Disease and Therapy
  • RNA Research and Splicing
  • RNA modifications and cancer
  • Cancer-related molecular mechanisms research
  • Cell Adhesion Molecules Research

Throughout their career, David E. Kuhl has been recognized with several awards and honors. These include the Japan Prize in 2011 for contributions to the technological integration of medical science and engineering, specifically in tomographic imaging in nuclear medicine.

In addition, they have been elected as a member of the National Academy of Medicine since 1989 and hold membership in the Association of American Physicians.

Best Publications

  • TOMOGRAPHIC MEASUREMENT OF LOCAL CEREBRAL GLUCOSE METABOLIC RATE IN HUMANS WITH (F-18)2-FLUORO-2-DEOXY-D-GLUCOSE: VALIDATION OF METHOD

    M. E. Phelps;S. C. Huang;E. J. Hoffman;C. Selin

  • Metabolic Reduction in the Posterior Cingulate Cortex in Very Early Alzheimer's Disease

    Saroshi Minoshima;Bruno Giordani;Stanley Berent;Kirk A. Frey

  • The [18F]fluorodeoxyglucose method for the measurement of local cerebral glucose utilization in man.

    M Reivich;D Kuhl;A Wolf;J Greenberg

  • A Diagnostic Approach in Alzheimer's Disease Using Three-Dimensional Stereotactic Surface Projections of Fluorine-18-FDG PET

    Satoshi Minoshima;Kirk A. Frey;Kirk A. Frey;Robert A. Koeppe;Norman L. Foster

  • Noninvasive determination of local cerebral metabolic rate of glucose in man

    S. C. Huang;M. E. Phelps;E. J. Hoffman;K. Sideris

  • Noninvasive quantification of regional blood flow in the human heart using N-13 ammonia and dynamic positron emission tomographic imaging

    Gary D. Hutchins;Markus Schwaiger;Karen C. Rosenspire;Janine Krivokapich

  • Cerebral metabolism and atrophy in huntington's disease determined by 18FDG and computed tomographic scan

    David E. Kuhl;Michael E. Phelps;Charles H. Markham;E. Jeffrey Metter

  • Quantifying Local Cerebral Blood Flow by N-Isopropyl-p-[123I]Iodoamphetamine (IMP) Tomography

    David E. Kuhl;Jorge R. Barrio;Sung-Cheng Huang;Carl Selin

  • Alzheimer's disease versus Dementia with Lewy bodies : Cerebral metabolic distinction with autopsy confirmation

    Satoshi Minoshima;Norman L. Foster;Anders A. F. Sima;Kirk A. Frey

  • N-13 ammonia as an indicator of myocardial blood flow.

    H R Schelbert;M E Phelps;S C Huang;N S MacDonald

  • Anatomic Standardization: Linear Scaling and Nonlinear Warping of Functional Brain Images

    Satoshi Minoshima;Robert A. Koeppe;Kirk A. Frey;Kirk A. Frey;David E. Kuhl

  • Epileptic patterns of local cerebral metabolism and perfusion in humans determined by emission computed tomography of 18FDG and 13NH3.

    David E. Kuhl;Jerome Engel;Michael E. Phelps;Carl Selin

  • Tomographic mapping of human cerebral metabolism Auditory stimulation

    John C. Mazziotta;Michael E. Phelps;Richard E. Carson;David E. Kuhl

  • Image Separation Radioisotope Scanning

    David E. Kuhl;Roy Q. Edwards

  • In vivo mapping of cholinergic terminals in normal aging, Alzheimer's disease, and Parkinson's disease

    D. E. Kuhl;S. Minoshima;J. A. Fessler;K. A. Frey;K. A. Frey

  • Labeled 2-deoxy-D-glucose analogs. 18F-labeled 2-deoxy-2-fluoro-D-glucose, 2-deoxy-2-fluoro-D-mannose and 14C-2-deoxy-2-fluoro-D-glucose

    T. Ido;C-N. Wan;V. Casella;J. S. Fowler

  • Effects of stroke on local cerebral metabolism and perfusion: Mapping by emission computed tomography of 18FDG and 13NH3

    David E. Kuhl;Michael E. Phelps;Arthur P. Kowell;E. Jeffrey Metter

  • Pathological findings underlying focal temporal lobe hypometabolism in partial epilepsy

    Jr J Engel;WJ Brown;DE Kuhl;ME Phelps

  • Effects of human aging on patterns of local cerebral glucose utilization determined by the [18F]fluorodeoxyglucose method.

    Kuhl De;Metter Ej;Riege Wh;Phelps Me

  • Quantitation in positron emission computed tomography: 5. Physical--anatomical effects.

    John C. Mazziotta;Michael E. Phelps;David Plummer;David E. Kuhl

Frequent Co-Authors

Kirk A. Frey
Kirk A. Frey University of Michigan–Ann Arbor
Robert A. Koeppe
Robert A. Koeppe University of Michigan–Ann Arbor
Michael R. Kilbourn
Michael R. Kilbourn University of Michigan–Ann Arbor
Satoshi Minoshima
Satoshi Minoshima University of Utah
Norman L. Foster
Norman L. Foster University of Utah
Michael E. Phelps
Michael E. Phelps University of California, Los Angeles
Roger L. Albin
Roger L. Albin University of Michigan–Ann Arbor
Stanley Berent
Stanley Berent University of Michigan–Ann Arbor
Bruno Giordani
Bruno Giordani University of Michigan–Ann Arbor
Markus Schwaiger
Markus Schwaiger Technical University of Munich

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Pursuing a medical career in the USA isn’t limited to MD programs—there are diverse online degrees and alternative pathways to consider. Many students begin their healthcare journey through nursing, which offers numerous online options tailored to different backgrounds and goals.

For those seeking affordable and flexible advanced study, an online PhD in nursing can open doors to leadership roles and academia. Registered nurses aiming to advance can consider the cheapest RN to BSN programs, which offer a practical and economical path to further education.

If you hold a non-nursing bachelor’s degree but want to switch careers, direct entry MSN programs online allow you to fast-track your entry into nursing leadership positions. For prospective nurses looking for accessible schools, explore the list of easy nursing schools to get into—some offer flexible admission criteria and online formats.

These online pathways offer flexibility, affordability, and a chance to start or advance your healthcare career from anywhere, fitting a variety of backgrounds and aspirations.

Best Scientists Citing David E. Kuhl

Recently Published Articles