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Neuroscience

D-Index
38
Citations
6728
World Ranking
8517
National Ranking
464

Overview

Daniela Puzzo is affiliated with the University of Catania in Italy. Their research focuses broadly on medicine and neuroscience, with significant contributions in biochemistry, genetics, and molecular biology. The scientist's work further specializes in subfields such as physiology, cellular and molecular neuroscience, molecular biology, pharmacology, and behavioral neuroscience.

The main topics covered in Daniela Puzzo's research include Alzheimer's disease research and treatments, neuroscience and neuropharmacology research, cholinesterase and neurodegenerative diseases, nicotinic acetylcholine receptors study, receptor mechanisms and signaling, stress responses and cortisol, and tryptophan and brain disorders.

Frequent co-authors collaborating with Daniela Puzzo are:

  • Walter Gulisano
  • Maria Rosaria Tropea
  • Claudio Grassi
  • Ottavio Arancio
  • Fiorenzo Conti

The scientist has published in various academic venues. Most frequent among them are:

  • Alzheimer s & Dementia
  • Frontiers in Molecular Neuroscience
  • Neurobiology of Stress
  • Journal of Clinical Investigation
  • Frontiers in Pharmacology

Selected recent publications by Daniela Puzzo include:

  • "Tau is not necessary for amyloid-β-induced synaptic and memory impairments" (2020), Journal of Clinical Investigation
  • "A novel arousal-based individual screening reveals susceptibility and resilience to PTSD-like phenotypes in mice" (2020), Neurobiology of Stress
  • "Antioxidant Activity of Fluoxetine and Vortioxetine in a Non-Transgenic Animal Model of Alzheimer's Disease" (2021), Frontiers in Pharmacology
  • "Nitric oxide/cGMP/CREB pathway and amyloid-beta crosstalk: From physiology to Alzheimer's disease" (2022), Free Radical Biology and Medicine
  • "Genetic deletion of α7 nicotinic acetylcholine receptors induces an age-dependent Alzheimer's disease-like pathology" (2021), Progress in Neurobiology

Daniela Puzzo's body of work integrates molecular approaches and neuropharmacological perspectives, addressing mechanisms behind neurodegenerative diseases, especially Alzheimer's disease. Their exploration of receptor systems like nicotinic acetylcholine receptors and signaling pathways reflects a focus on both physiological and pathological processes.

Best Publications

  • Picomolar amyloid-beta positively modulates synaptic plasticity and memory in hippocampus.

    Daniela Puzzo;Lucia Privitera;Elena Leznik;Mauro Fà

  • RAGE potentiates Aβ-induced perturbation of neuronal function in transgenic mice

    Ottavio Arancio;Hui Ping Zhang;Xi Chen;Chang Lin

  • Endogenous amyloid-β is necessary for hippocampal synaptic plasticity and memory.

    Daniela Puzzo;Lucia Privitera;Lucia Privitera;Mauro Fa;Agnieszka Staniszewski

  • Phosphodiesterase 5 Inhibition Improves Synaptic Function, Memory, and Amyloid-β Load in an Alzheimer's Disease Mouse Model

    Daniela Puzzo;Agnieszka Staniszewski;Shi Xian Deng;Lucia Privitera

  • Amyloid-β Peptide Inhibits Activation of the Nitric Oxide/cGMP/cAMP-Responsive Element-Binding Protein Pathway during Hippocampal Synaptic Plasticity

    Daniela Puzzo;Ottavio Vitolo;Fabrizio Trinchese;Joel P. Jacob

  • Extracellular Tau Oligomers Produce An Immediate Impairment of LTP and Memory.

    M. Fá;D. Puzzo;D. Puzzo;R. Piacentini;Agnieszka Staniszewski

  • Role of Amyloid-β and Tau Proteins in Alzheimer’s Disease: Confuting the Amyloid Cascade

    Walter Gulisano;Daniele Maugeri;Marian A Baltrons;Marian A Baltrons;Mauro Fà

  • Behavioral assays with mouse models of Alzheimer's disease: practical considerations and guidelines.

    Daniela Puzzo;Linda Lee;Agostino Palmeri;Giorgio Calabrese

  • Rodent models for Alzheimer’s disease drug discovery

    Daniela Puzzo;Walter Gulisano;Agostino Palmeri;Ottavio Arancio

  • A GluR1-cGKII Interaction Regulates AMPA Receptor Trafficking

    Yafell Serulle;Shuang Zhang;Ipe Ninan;Daniela Puzzo

  • LTP and memory impairment caused by extracellular Aβ and Tau oligomers is APP-dependent.

    Daniela Puzzo;Roberto Piacentini;Mauro Fá;Walter Gulisano

  • Amyloid-β peptide: Dr. Jekyll or Mr. Hyde?

    Daniela Puzzo;Ottavio Arancio

  • Synaptic Therapy in Alzheimer’s Disease: A CREB-centric Approach

    Andrew Franklin Teich;Russell E. Nicholls;Daniela Puzzo;Jole Fiorito

  • THE KEYSTONE OF ALZHEIMER PATHOGENESIS MIGHT BE SOUGHT IN Aβ PHYSIOLOGY

    Daniela Puzzo;Walter Gulisano;Ottavio Arancio;Agostino Palmeri

  • Intracellular accumulation of amyloid-β (Aβ) protein plays a major role in Aβ-induced alterations of glutamatergic synaptic transmission and plasticity.

    Cristian Ripoli;Sara Cocco;Domenica Donatella Li Puma;Roberto Piacentini

  • Hormetic effect of amyloid-beta peptide in synaptic plasticity and memory

    Daniela Puzzo;Lucia Privitera;Agostino Palmeri

  • Improved long-term memory via enhancing cGMP-PKG signaling requires cAMP-PKA signaling.

    Eva Bollen;Daniela Puzzo;Kris Rutten;Lucia Privitera

  • A key role for TGF-β1 in hippocampal synaptic plasticity and memory.

    Filippo Caraci;Walter Gulisano;Chiara A. Guida;Agata A. R. Impellizzeri

  • Role of phosphodiesterase 5 in synaptic plasticity and memory.

    Daniela Puzzo;Salvatore Sapienza;Ottavio Arancio;Agostino Palmeri

  • Effect of phosphodiesterase-5 inhibition on apoptosis and beta amyloid load in aged mice

    Daniela Puzzo;Carla Loreto;Salvatore Giunta;Giuseppe Musumeci

Frequent Co-Authors

Ottavio Arancio
Ottavio Arancio Columbia University
Claudio Grassi
Claudio Grassi Catholic University of the Sacred Heart
Fiorenzo Conti
Fiorenzo Conti Marche Polytechnic University
Marcello Melone
Marcello Melone Marche Polytechnic University
Rudi D'Hooge
Rudi D'Hooge KU Leuven
Elena Gardella
Elena Gardella University of Southern Denmark
Douglas G. Walker
Douglas G. Walker Arizona State University
Nicholas M. Kanaan
Nicholas M. Kanaan Michigan State University
Agata Copani
Agata Copani University of Catania
Arjan Blokland
Arjan Blokland Maastricht University

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