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Helle S. Waagepetersen

Helle S. Waagepetersen

D-Index & Metrics

Biology and Biochemistry

D-Index
67
Citations
14083
World Ranking
8313
National Ranking
78

Overview

Helle S. Waagepetersen is affiliated with the University of Copenhagen in Denmark. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, Neuroscience, and Medicine, with a significant focus on Molecular Biology and Cellular and Molecular Neuroscience. Additional subfields of expertise include Physiology, Neurology, and Biological Psychiatry.

Their work covers a variety of topics related to neuroscience and neuropharmacology research, mitochondrial function and pathology, Alzheimer's disease research and treatments, neuroinflammation and neurodegeneration mechanisms, tryptophan and brain disorders, metabolism and genetic disorders, as well as diet and metabolism studies.

Recent papers in their research portfolio include:

  • Glutamate metabolism and recycling at the excitatory synapse in health and neurodegeneration, 2021, Neuropharmacology
  • Deficient astrocyte metabolism impairs glutamine synthesis and neurotransmitter homeostasis in a mouse model of Alzheimer's disease, 2020, Neurobiology of Disease
  • Hippocampal disruptions of synaptic and astrocyte metabolism are primary events of early amyloid pathology in the 5xFAD mouse model of Alzheimer's disease, 2021, Cell Death and Disease
  • Functional Metabolic Mapping Reveals Highly Active Branched-Chain Amino Acid Metabolism in Human Astrocytes, Which Is Impaired in iPSC-Derived Astrocytes in Alzheimer's Disease, 2021, Frontiers in Aging Neuroscience
  • Glutamate-glutamine homeostasis is perturbed in neurons and astrocytes derived from patient iPSC models of frontotemporal dementia, 2020, Molecular Brain

Their frequent co-authors include Blanca I. Aldana, Jens V. Andersen, Kristine Freude, Arne Schousboe, and Sofie K. Christensen.

In terms of publication venues, Waagepetersen frequently contributes to the following journals:

  • Glia
  • Neurochemical Research
  • Journal of Neurochemistry
  • Neuropharmacology
  • Neurobiology of Disease

Best Publications

  • The glutamate/GABA-glutamine cycle: aspects of transport, neurotransmitter homeostasis and ammonia transfer.

    Lasse K. Bak;Arne Schousboe;Helle S. Waagepetersen

  • The transcriptome and metabolic gene signature of protoplasmic astrocytes in the adult murine cortex.

    Ditte Lovatt;Ursula Sonnewald;Helle S. Waagepetersen;Arne Schousboe

  • Neuronal and astrocytic shuttle mechanisms for cytosolic-mitochondrial transfer of reducing equivalents: current evidence and pharmacological tools.

    Mary C. McKenna;Helle S. Waagepetersen;Arne Schousboe;Ursula Sonnewald

  • Glutamate Metabolism in the Brain Focusing on Astrocytes

    Arne Schousboe;Susanna Scafidi;Lasse Kristoffer Bak;Helle S Waagepetersen

  • Glutamate metabolism and recycling at the excitatory synapse in health and neurodegeneration

    Jens V. Andersen;Kia H. Markussen;Emil Jakobsen;Arne Schousboe

  • Astrocytic Control of Biosynthesis and Turnover of the Neurotransmitters Glutamate and GABA

    Arne Schousboe;Lasse Kristoffer Bak;Helle Sønderby Waagepetersen

  • Trafficking between glia and neurons of TCA cycle intermediates and related metabolites

    Arne Schousboe;Niels Westergaard;Helle S. Waagepetersen;Orla M. Larsson

  • Energy Metabolism of the Brain

    Mary C. McKenna;Gerald A. Dienel;Ursula Sonnewald;Helle S. Waagepetersen

  • Brain glycogen-new perspectives on its metabolic function and regulation at the subcellular level.

    Linea Frimodt Obel;Margit Silke Müller;Anne Byriel Walls;Helle Mark Sickmann

  • A Possible Role of Alanine for Ammonia Transfer Between Astrocytes and Glutamatergic Neurons

    Helle S Waagepetersen;Ursula Sonnewald;Orla M Larsson;Arne Schousboe

  • The Glutamine–Glutamate/GABA Cycle: Function, Regional Differences in Glutamate and GABA Production and Effects of Interference with GABA Metabolism

    Anne B. Walls;Helle S. Waagepetersen;Lasse K. Bak;Arne Schousboe

  • Role of astrocytes in glutamate homeostasis: implications for excitotoxicity.

    Arne Schousboe;Helle S. Waagepetersen

  • Glutamine in the central nervous system: function and dysfunction.

    Jan Albrecht;Ursula Sonnewald;Helle S Waagepetersen;Arne Schousboe

  • The GABA paradox: multiple roles as metabolite, neurotransmitter, and neurodifferentiative agent.

    Helle S. Waagepetersen;Ursula Sonnewald;Arne Schousboe

  • Astrocyte glycogen metabolism is required for neural activity during aglycemia or intense stimulation in mouse white matter

    Angus M. Brown;Helle M. Sickmann;Keld Fosgerau;Trine M. Lund

  • Glucose is necessary to maintain neurotransmitter homeostasis during synaptic activity in cultured glutamatergic neurons.

    Lasse K Bak;Arne Schousboe;Ursula Sonnewald;Helle S Waagepetersen

  • Primary Cultures of Astrocytes: Their Value in Understanding Astrocytes in Health and Disease

    Sofie C. Lange;Lasse K. Bak;Helle S. Waagepetersen;Arne Schousboe

  • Role of astrocytic transport processes in glutamatergic and GABAergic neurotransmission.

    A. Schousboe;A. Sarup;L.K. Bak;H.S. Waagepetersen

  • Robust glycogen shunt activity in astrocytes: Effects of glutamatergic and adrenergic agents.

    A.B. Walls;C.M. Heimbürger;S.D. Bouman;A. Schousboe

  • Functional significance of brain glycogen in sustaining glutamatergic neurotransmission

    Helle M. Sickmann;Anne B. Walls;Anne B. Walls;Arne Schousboe;Stephan D. Bouman

Frequent Co-Authors

Arne Schousboe
Arne Schousboe University of Copenhagen
Ursula Sonnewald
Ursula Sonnewald Norwegian University of Science and Technology
Pierre Maechler
Pierre Maechler University of Geneva
Linda H. Bergersen
Linda H. Bergersen University of Oslo
Chiye Aoki
Chiye Aoki New York University
Albert Gjedde
Albert Gjedde University of Copenhagen
Poul Hyttel
Poul Hyttel University of Copenhagen
Paul A. Rosenberg
Paul A. Rosenberg Boston Children's Hospital
Heikki Tanila
Heikki Tanila University of Eastern Finland
Jan Albrecht
Jan Albrecht Polish Academy of Sciences

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