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Neuroscience

D-Index
55
Citations
13106
World Ranking
4666
National Ranking
2104

Overview

Gerald A. Dienel is affiliated with the University of Arkansas for Medical Sciences in the United States. Their research focuses primarily on biochemical and neurological processes at the molecular and cellular levels, with publications spanning biochemistry, genetics, molecular biology, medicine, and neuroscience.

The scientist's main fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine
  • Neuroscience

Subfields that define their research interests are:

  • Molecular Biology
  • Cellular and Molecular Neuroscience
  • Neurology
  • Physiology
  • Clinical Biochemistry

Dienel's work covers a variety of topics such as:

  • Neuroscience and Neuropharmacology Research
  • Mitochondrial Function and Pathology
  • Diet and Metabolism Studies
  • Metabolomics and Mass Spectrometry Studies
  • Metabolism and Genetic Disorders
  • Epilepsy Research and Treatment
  • Advanced MRI Techniques and Applications

Among the frequent co-authors are:

  • Douglas L. Rothman
  • Silvia Mangia
  • Kevin L. Behar
  • Karin Borges
  • Mauro DiNuzzo

Many of Dienel's studies have been published in a select group of scientific journals, including:

  • Journal of Neurochemistry
  • Neurochemical Research
  • Fluids and Barriers of the CNS
  • Neuroscience & Biobehavioral Reviews
  • Epilepsia

Selected recent publications provide insights into the scientist's research focus and contributions:

  • Brain energy metabolism: A roadmap for future research, 2024, Journal of Neurochemistry
  • Reevaluation of Astrocyte-Neuron Energy Metabolism with Astrocyte Volume Fraction Correction: Impact on Cellular Glucose Oxidation Rates, Glutamate-Glutamine Cycle Energetics, Glycogen Levels and Utilization Rates vs. Exercising Muscle, and Na+/K+ Pumping Rates, 2020, Neurochemical Research
  • Stop the rot. Enzyme inactivation at brain harvest prevents artifacts, 2021, Journal of Neurochemistry
  • Neurovascular coupling is optimized to compensate for the increase in proton production from nonoxidative glycolysis and glycogenolysis during brain activation and maintain homeostasis of pH, pCO2, and pO2, 2023, Journal of Neurochemistry
  • Potential new roles for glycogen in epilepsy, 2022, Epilepsia

Best Publications

  • Sugar for the brain: the role of glucose in physiological and pathological brain function

    Philipp Mergenthaler;Ute Lindauer;Gerald A. Dienel;Andreas Meisel

  • Brain Glucose Metabolism: Integration of Energetics with Function

    Gerald A. Dienel

  • Energy metabolism in astrocytes: high rate of oxidative metabolism and spatiotemporal dependence on glycolysis/glycogenolysis.

    Leif Hertz;Liang Peng;Gerald A Dienel

  • Brain lactate metabolism: the discoveries and the controversies.

    Gerald A Dienel

  • Regional accumulation of calcium in postischemic rat brain.

    Gerald A. Dienel

  • Glucose and lactate metabolism during brain activation.

    Gerald A. Dienel;Leif Hertz

  • Regional protein synthesis in rat brain following acute hemispheric ischemia.

    G. A. Dienel;W. A. Pulsinelli;T. E. Duffy

  • High Glycogen Levels in Brains of Rats with Minimal Environmental Stimuli: Implications for Metabolic Contributions of Working Astrocytes

    Nancy F Cruz;Gerald A Dienel

  • Receptor-mediated glutamate release from volume sensitive channels in astrocytes

    Takahiro Takano;Jian Kang;Jyoti K. Jaiswal;Sanford M. Simon

  • Cerebral oxygen/glucose ratio is low during sensory stimulation and rises above normal during recovery: excess glucose consumption during stimulation is not accounted for by lactate efflux from or accumulation in brain tissue.

    Peter Lund Madsen;Nancy F. Cruz;Louis Sokoloff;Gerald A. Dienel

  • Nutrition during brain activation: does cell-to-cell lactate shuttling contribute significantly to sweet and sour food for thought?

    Gerald A. Dienel;Nancy F. Cruz

  • Energy Metabolism of the Brain

    Mary C. McKenna;Gerald A. Dienel;Ursula Sonnewald;Helle S. Waagepetersen

  • Induction of brain ornithine decarboxylase during recovery from metabolic, mechanical, thermal, or chemical injury.

    Gerald A. Dienel;Nancy F. Cruz

  • Lactate transport and transporters: general principles and functional roles in brain cells

    Leif Hertz;Gerald A. Dienel

  • Astrocytes are poised for lactate trafficking and release from activated brain and for supply of glucose to neurons.

    Gautam K. Gandhi;Nancy F. Cruz;Kelly K. Ball;Gerald A. Dienel

  • Fueling and imaging brain activation.

    Gerald A Dienel

  • Energy metabolism in the brain.

    Leif Hertz;Gerald A Dienel

  • Astrocytic contributions to bioenergetics of cerebral ischemia.

    Gerald A. Dienel;Leif Hertz

  • Lack of appropriate stoichiometry: Strong evidence against an energetically important astrocyte–neuron lactate shuttle in brain

    Gerald A. Dienel

  • Synthesis of Heat Shock Proteins in Rat Brain Cortex After Transient Ischemia

    Gerald A. Dienel;Marika Kiessling;Michael Jacewicz;William A. Pulsinelli

Frequent Co-Authors

Louis Sokoloff
Louis Sokoloff National Institutes of Health
Gary E. Gibson
Gary E. Gibson Cornell University
Thérèse M. Jay
Thérèse M. Jay Centre national de la recherche scientifique, CNRS
Takahiro Takano
Takahiro Takano University of Rochester
Robert G. Kalb
Robert G. Kalb Northwestern University
Albert Gjedde
Albert Gjedde University of Copenhagen
Marie E. Gibbs
Marie E. Gibbs Monash University
Harriet Baker
Harriet Baker Cornell University
Sami I. Harik
Sami I. Harik University of Arkansas for Medical Sciences
Kevin L. Behar
Kevin L. Behar Yale University

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