Yoshitomo Oka

Overview

Best Publications

• Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms

  Jun Ichi Miyazaki;Kimi Araki;Eiji Yamato;Hiroshi Ikegami

  1805
  Citations

• International clinical harmonization of glycated hemoglobin in Japan: From Japan Diabetes Society to National Glycohemoglobin Standardization Program values.

  Atsunori Kashiwagi;Masato Kasuga;Eiichi Araki;Yoshitomo Oka

  1222
  Citations

• A gene encoding a transmembrane protein is mutated in patients with diabetes mellitus and optic atrophy (Wolfram syndrome)

  Hiroshi Inoue;Yukio Tanizawa;Jon Wasson;Philip Behn

  912
  Citations

• Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus.

  Kazuki Yasuda;Kazuaki Miyake;Yukio Horikawa;Kazuo Hara

  907
  Citations

• Identification and functional analysis of sulfonylurea receptor 1 variants in Japanese patients with NIDDM.

  Y Ohta;Y Tanizawa;H Inoue;T Hosaka

  845
  Citations

• Pancreatic beta cell line MIN6 exhibits characteristics of glucose metabolism and glucose-stimulated insulin secretion similar to those of normal islets.

  H. Ishihara;T. Asano;K. Tsukuda;H. Katagiri

  583
  Citations

• Long-Term Clinical Effects of Epalrestat, an Aldose Reductase Inhibitor, on Diabetic Peripheral Neuropathy: The 3-year, multicenter, comparative Aldose Reductase Inhibitor-Diabetes Complications Trial

  Nigishi Hotta;Yasuo Akanuma;Ryuzo Kawamori;Kempei Matsuoka

  439
  Citations

• Wolfram syndrome 1 gene negatively regulates ER stress signaling in rodent and human cells

  Sonya G. Fonseca;Shinsuke Ishigaki;Christine M. Oslowski;Simin Lu

  432
  Citations

• WFS1 Is a Novel Component of the Unfolded Protein Response and Maintains Homeostasis of the Endoplasmic Reticulum in Pancreatic β-Cells *

  Sonya G. Fonseca;Mariko Fukuma;Kathryn L. Lipson;Linh X. Nguyen

  397
  Citations

• Molecular mimicry by Helicobacter pylori CagA protein may be involved in the pathogenesis of H. pylori‐associated chronic idiopathic thrombocytopenic purpura

  Toru Takahashi;Toshiaki Yujiri;Kenji Shinohara;Yusuke Inoue

  395
  Citations

• WFS1 (Wolfram syndrome 1) gene product: predominant subcellular localization to endoplasmic reticulum in cultured cells and neuronal expression in rat brain

  Koumei Takeda;Hiroshi Inoue;Yukio Tanizawa;Yumiko Matsuzaki

  381
  Citations

• The Pro12→Ala Substitution in PPAR-γ Is Associated With Resistance to Development of Diabetes in the General Population: Possible Involvement in Impairment of Insulin Secretion in Individuals With Type 2 Diabetes

  Hiroyuki Mori;Hiroshi Ikegami;Yoshihiko Kawaguchi;Susumu Seino

  335
  Citations

• WFS1-deficiency increases endoplasmic reticulum stress, impairs cell cycle progression and triggers the apoptotic pathway specifically in pancreatic β-cells

  Takahiro Yamada;Hisamitsu Ishihara;Akira Tamura;Rui Takahashi

  324
  Citations

• Neuronal pathway from the liver modulates energy expenditure and systemic insulin sensitivity.

  Kenji Uno;Hideki Katagiri;Tetsuya Yamada;Yasushi Ishigaki

  323
  Citations

• Adiposity and Cardiovascular Disorders Disturbance of the Regulatory System Consisting of Humoral and Neuronal Signals

  Hideki Katagiri;Tetsuya Yamada;Yoshitomo Oka

  316
  Citations

• MEK kinase 1 gene disruption alters cell migration and c-Jun NH2-terminal kinase regulation but does not cause a measurable defect in NF-kappa B activation

  Toshiaki Yujiri;Margaret Ware;Margaret Ware;Christian Widmann;Christian Widmann;Ryan Oyer

  309
  Citations

• Disruption of the WFS1 gene in mice causes progressive β-cell loss and impaired stimulus–secretion coupling in insulin secretion

  Hisamitsu Ishihara;Satoshi Takeda;Akira Tamura;Rui Takahashi

  308
  Citations

• Dexamethasone-induced insulin resistance in 3T3-L1 adipocytes is due to inhibition of glucose transport rather than insulin signal transduction.

  Hideyuki Sakoda;Takehide Ogihara;Motonobu Anai;Makoto Funaki

  307
  Citations

• Direct demonstration of rapid insulin-like growth factor II Receptor internalization and recycling in rat adipocytes. Insulin stimulates 125I-insulin-like growth factor II degradation by modulating the IGF-II receptor recycling process.

  Y Oka;L M Rozek;M P Czech

  291
  Citations

• Humoral regulation of resistin expression in 3T3-L1 and mouse adipose cells

  Nobuhiro Shojima;Hideyuki Sakoda;Takehide Ogihara;Takehide Ogihara;Midori Fujishiro;Midori Fujishiro

  289
  Citations