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Hisamitsu Ishihara

Hisamitsu Ishihara

Nihon University
Japan

D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
12914
World Ranking
10856
National Ranking
740

Hisamitsu Ishihara publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Hisamitsu Ishihara sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 153 publications — 28th percentile

28% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Hisamitsu Ishihara D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Hisamitsu Ishihara sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 62 D-Index — 46th percentile

46% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Hisamitsu Ishihara is affiliated with Nihon University in Japan and has contributed extensively to research in the fields of medicine, biochemistry, genetics, and molecular biology. Their scholarly work spans a diverse range of topics with a significant focus on pancreatic function and diabetes, metabolism, diabetes and cancer, and cardiovascular health.

Their recent publications demonstrate involvement in both clinical and molecular research related to diabetes and its complications. Notable papers include:

  • Identification of serum metabolome signatures associated with retinal and renal complications of type 2 diabetes (2023), published in Communications Medicine
  • Seasonal variation in hydration status among community-dwelling elderly in Japan (2020), published in Geriatrics and Gerontology International
  • Comparison of tofogliflozin versus glimepiride as the third oral agent added to metformin plus a dipeptidyl peptidase-4 inhibitor in Japanese patients with type 2 diabetes: A randomized, 24-week, open-label, controlled trial (STOP-OB) (2020), published in Diabetes Obesity and Metabolism
  • Metabolism-secretion coupling in glucose-stimulated insulin secretion (2022), published in Diabetology International
  • Effects of GLP-1RA and SGLT2i, Alone or in Combination, on Mouse Models of Type 2 Diabetes Representing Different Disease Stages (2021), published in International Journal of Molecular Sciences

The frequent co-authors collaborating with Ishihara across multiple publications include:

  • Kentaro Watanabe
  • Midori Fujishiro
  • Sho Tanaka
  • Genta Kohno
  • Masahiro Takubo

Hisamitsu Ishihara's work has been featured in several recurring publication venues, including:

  • Diabetology International
  • Therapeutics and Clinical Risk Management
  • Experimental and Clinical Endocrinology & Diabetes
  • Communications Medicine
  • Geriatrics and Gerontology International

Their research interests cover multiple specialized subfields including surgery, molecular biology, endocrinology, diabetes and metabolism, cardiology and cardiovascular medicine, and epidemiology. The main topics addressed by their research are:

  • Pancreatic function and diabetes
  • Diabetes treatment and management
  • Metabolism, diabetes, and cancer
  • Liver disease diagnosis and treatment
  • Diabetes and associated disorders
  • Cardiovascular disease and adiposity
  • Pancreatitis pathology and treatment

This comprehensive research profile reflects diverse and interdisciplinary efforts focused on understanding and managing diabetes and related metabolic disorders through both clinical trials and molecular biology perspectives.

Best Publications

  • Pancreatic beta cell line MIN6 exhibits characteristics of glucose metabolism and glucose-stimulated insulin secretion similar to those of normal islets.

    H. Ishihara;T. Asano;K. Tsukuda;H. Katagiri

  • Islet |[beta]|-cell secretion determines glucagon release from neighbouring |[alpha]|-cells

    Hisamitsu Ishihara;Pierre Maechler;Asllan Gjinovci;Pedro-Luis Herrera

  • Wolfram syndrome 1 gene negatively regulates ER stress signaling in rodent and human cells

    Sonya G. Fonseca;Shinsuke Ishigaki;Christine M. Oslowski;Simin Lu

  • Type I Phosphatidylinositol-4-phosphate 5-Kinases CLONING OF THE THIRD ISOFORM AND DELETION/SUBSTITUTION ANALYSIS OF MEMBERS OF THIS NOVEL LIPID KINASE FAMILY

    Hisamitsu Ishihara;Yoshikazu Shibasaki;Nobuaki Kizuki;Takako Wada

  • A critical role for a Rho-associated kinase, p160ROCK, in determining axon outgrowth in mammalian CNS neurons

    Haruhiko Bito;Tomoyuki Furuyashiki;Hisamitsu Ishihara;Yoshikazu Shibasaki

  • Type Iα phosphatidylinositol-4-phosphate 5-kinase mediates Rac-dependent actin assembly

    Kimberley F. Tolias;John H. Hartwig;John H. Hartwig;Hisamitsu Ishihara;Yoshikazu Shibasaki

  • WFS1-deficiency increases endoplasmic reticulum stress, impairs cell cycle progression and triggers the apoptotic pathway specifically in pancreatic β-cells

    Takahiro Yamada;Hisamitsu Ishihara;Akira Tamura;Rui Takahashi

  • Neuronal pathway from the liver modulates energy expenditure and systemic insulin sensitivity.

    Kenji Uno;Hideki Katagiri;Tetsuya Yamada;Yasushi Ishigaki

  • Disruption of the WFS1 gene in mice causes progressive β-cell loss and impaired stimulus–secretion coupling in insulin secretion

    Hisamitsu Ishihara;Satoshi Takeda;Akira Tamura;Rui Takahashi

  • Overexpression of Catalytic Subunit p110α of Phosphatidylinositol 3-Kinase Increases Glucose Transport Activity with Translocation of Glucose Transporters in 3T3-L1 Adipocytes

    Hideki Katagiri;Tomoichiro Asano;Hisamitsu Ishihara;Kouichi Inukai

  • Cloning of cDNAs encoding two isoforms of 68-kDa type I phosphatidylinositol-4-phosphate 5-kinase.

    Hisamitsu Ishihara;Yoshikazu Shibasaki;Nobuaki Kizuki;Hideki Katagiri

  • Effect of an intensified multifactorial intervention on cardiovascular outcomes and mortality in type 2 diabetes (J-DOIT3): an open-label, randomised controlled trial

    Kohjiro Ueki;Takayoshi Sasako;Yukiko Okazaki;Masayuki Kato

  • Regulation of Pancreatic β Cell Mass by Neuronal Signals from the Liver

    Junta Imai;Hideki Katagiri;Tetsuya Yamada;Yasushi Ishigaki

  • Overexpression of monocarboxylate transporter and lactate dehydrogenase alters insulin secretory responses to pyruvate and lactate in β cells

    Hisamitsu Ishihara;Haiyan Wang;Lester R. Drewes;Claes B. Wollheim

  • Impact of plasma oxidized low-density lipoprotein removal on atherosclerosis.

    Yasushi Ishigaki;Hideki Katagiri;Junhong Gao;Tetsuya Yamada

  • The role of N-glycosylation of GLUT1 for glucose transport activity.

    T Asano;H Katagiri;K Takata;J L Lin

  • Massive Actin Polymerization Induced by Phosphatidylinositol-4-phosphate 5-Kinase in Vivo

    Yoshikazu Shibasaki;Hisamitsu Ishihara;Nobuaki Kizuki;Tomoichiro Asano

  • ATF4-Mediated Induction of 4E-BP1 Contributes to Pancreatic β Cell Survival under Endoplasmic Reticulum Stress

    Suguru Yamaguchi;Hisamitsu Ishihara;Takahiro Yamada;Akira Tamura

  • Pdx1 level defines pancreatic gene expression pattern and cell lineage differentiation.

    Haiyan Wang;Pierre Maechler;Beate Ritz-Laser;Kerstin A. Hagenfeldt

  • Activation of Type I Phosphatidylinositol 4-Phosphate 5-Kinase Isoforms by the Rho GTPases, RhoA, Rac1, and Cdc42 *

    Paschal A. Oude Weernink;Konstantinos Meletiadis;Silvia Hommeltenberg;Matthias Hinz

Frequent Co-Authors

Yoshitomo Oka
Yoshitomo Oka Tohoku University
Yoshio Yazaki
Yoshio Yazaki University of Tokyo
Tomoichiro Asano
Tomoichiro Asano Hiroshima University
Motonobu Anai
Motonobu Anai University of Tokyo
Claes B. Wollheim
Claes B. Wollheim University of Geneva
Pierre Maechler
Pierre Maechler University of Geneva
Hironobu Sasano
Hironobu Sasano Tohoku University
Kuniaki Takata
Kuniaki Takata Gunma University
Christopher L. Carpenter
Christopher L. Carpenter GlaxoSmithKline (United Kingdom)
Jun-ichi Miyazaki
Jun-ichi Miyazaki Osaka University

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Best Scientists Citing Hisamitsu Ishihara

Yoshitomo Oka

Yoshitomo Oka

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Publications: 87

Pierre Maechler

Pierre Maechler

University of Geneva

Publications: 64

Claes B. Wollheim

Claes B. Wollheim

University of Geneva

Publications: 63

Guy A. Rutter

Guy A. Rutter

Imperial College London

Publications: 46

Tomoichiro Asano

Tomoichiro Asano

Hiroshima University

Publications: 44

Richard A. Anderson

Richard A. Anderson

University of Edinburgh

Publications: 34

Motonobu Anai

Motonobu Anai

University of Tokyo

Publications: 34

Fumihiko Urano

Fumihiko Urano

Washington University in St. Louis

Publications: 33

Per-Olof Berggren

Per-Olof Berggren

Karolinska Institute

Publications: 30

Takashi Kadowaki

Takashi Kadowaki

Toranomon Hospital

Publications: 30

Sulev Kõks

Sulev Kõks

Perron Institute for Neurological and Translational Science

Publications: 30

Eero Vasar

Eero Vasar

University of Tartu

Publications: 27

Patrik Rorsman

Patrik Rorsman

University of Oxford

Publications: 25

Yasunori Kanaho

Yasunori Kanaho

University of Tsukuba

Publications: 23

Frans Schuit

Frans Schuit

KU Leuven

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Rohit N. Kulkarni

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