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Hiroki Kurihara

Hiroki Kurihara

D-Index & Metrics

Medicine

D-Index
81
Citations
40846
World Ranking
16380
National Ranking
515

Overview

Hiroki Kurihara is a researcher affiliated with the University of Tokyo in Japan. Their work primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with a notable focus on Medicine as well. The scholar's research encompasses key subfields such as Molecular Biology, Cell Biology, Modeling and Simulation, Pulmonary and Respiratory Medicine, and Genetics.

The scientist's research topics include:

  • Congenital heart defects research
  • Mathematical Biology Tumor Growth
  • Developmental Biology and Gene Regulation
  • Angiogenesis and VEGF in Cancer
  • Lymphatic System and Diseases
  • Cancer-related molecular mechanisms research
  • Coronary Artery Anomalies

Kurihara has published multiple papers in a variety of venues, illustrating a focus on developmental and molecular biology, disease mechanisms, and genetic modeling. Frequent publication venues include bioRxiv (Cold Spring Harbor Laboratory), Scientific Reports, Proceedings of the National Academy of Sciences, iScience, and eLife.

Representative recent publications include:

  • Murine neonatal ketogenesis preserves mitochondrial energetics by preventing protein hyperacetylation, 2021, Nature Metabolism
  • Comprehensive analysis of a novel mouse model of the 22q11.2 deletion syndrome: a model with the most common 3.0-Mb deletion at the human 22q11.2 locus, 2020, Translational Psychiatry
  • The Hippo Signaling Pathway Components Lats and Yap Pattern Tead4 Activity to Distinguish Mouse Trophectoderm from Inner Cell Mass, 2021, UNC Libraries
  • Mammalian face as an evolutionary novelty, 2021, Proceedings of the National Academy of Sciences
  • Semaphorin3E-PlexinD1 signaling in coronary artery and lymphatic vessel development with clinical implications in myocardial recovery, 2021, iScience

The scientist's collaborations include frequent coauthors such as Yasunobu Uchijima, Sachiko Miyagawa-Tomita, Akiyasu Iwase, Hiroki Higashiyama, and Yukiko Kurihara, with multiple joint publications indicating sustained research partnerships.

Best Publications

  • A novel potent vasoconstrictor peptide produced by vascular endothelial cells.

    Masashi Yanagisawa;Hiroki Kurihara;Hiroki Kurihara;Sadao Kimura;Yoko Tomobe

  • A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection

    Hiroshi Suzuki;Hiroshi Suzuki;Yukiko Kurihara;Motohiro Takeya;Nobuo Kamada

  • Elevated blood pressure and craniofacial abnormalities in mice deficient in endothelin-1.

    Kurihara Y;Kurihara H;Suzuki H;Suzuki H;Kodama T

  • The Hippo signaling pathway components Lats and Yap pattern Tead4 activity to distinguish mouse trophectoderm from inner cell mass.

    Noriyuki Nishioka;Ken ichi Inoue;Kenjiro Adachi;Hiroshi Kiyonari

  • Endothelin stimulates c-fos and c-myc expression and proliferation of vascular smooth muscle cells.

    Issei Komuro;Hiroki Kurihara;Takao Sugiyama;Fumimaro Takaku

  • Hemodynamic shear stress stimulates endothelin production by cultured endothelial cells

    Masao Yoshizumi;Hiroki Kurihara;Takao Sugiyama;Fumimaro Takaku

  • Angiotensin II type 2 receptor overexpression activates the vascular kinin system and causes vasodilation.

    Yoshiaki Tsutsumi;Hiroaki Matsubara;Hiroya Masaki;Hiroki Kurihara

  • Transforming growth factor-β stimulates the expression of endothelin mRNA by vascular endothelial cells

    Hiroki Kurihara;Masao Yoshizumi;Takao Sugiyama;Fumimaro Takaku

  • Aortic arch malformations and ventricular septal defect in mice deficient in endothelin-1.

    Y Kurihara;H Kurihara;H Oda;K Maemura

  • Endothelin-1 is involved in mechanical stress-induced cardiomyocyte hypertrophy.

    Tsutomu Yamazaki;Issei Komuro;Sumiyo Kudoh;Yunzeng Zou

  • Genetic Polymorphism of 5,10-Methylenetetrahydrofolate Reductase (MTHFR) as a Risk Factor for Coronary Artery Disease

    H. Morita;J.-I. Taguchi;H. Kurihara;M. Kitaoka

  • ADAMTS-1: a metalloproteinase-disintegrin essential for normal growth, fertility, and organ morphology and function.

    Takayuki Shindo;Hiroki Kurihara;Kouji Kuno;Hitoshi Yokoyama

  • Vascular Abnormalities and Elevated Blood Pressure in Mice Lacking Adrenomedullin Gene

    Takayuki Shindo;Yukiko Kurihara;Hiroaki Nishimatsu;Nobuo Moriyama

  • A mouse model of vascular injury that induces rapid onset of medial cell apoptosis followed by reproducible neointimal hyperplasia.

    Masataka Sata;Yoshie Maejima;Fumiko Adachi;Keiko Fukino

  • A novel peptide vasoconstrictor, endothelin, is produced by vascular endothelium and modulates smooth muscle Ca2+ channels.

    Masashi Yanagisawa;Hiroki Kurihara;Sadao Kimura;Katsutoshi Goto

  • A signaling cascade involving endothelin-1, dHAND and Msx1 regulates development of neural-crest-derived branchial arch mesenchyme

    Tiffani Thomas;Hiroki Kurihara;Hiroyuki Yamagishi;Yukiko Kurihara

  • Hypotension and reduced nitric oxide-elicited vasorelaxation in transgenic mice overexpressing endothelial nitric oxide synthase.

    Yoshitaka Ohashi;Seinosuke Kawashima;Ken-ichi Hirata;Tomoya Yamashita

  • Multiple renal cysts, urinary concentration defects, and pulmonary emphysematous changes in mice lacking TAZ

    Ryosuke Makita;Yasunobu Uchijima;Koichi Nishiyama;Tomokazu Amano

  • Interleukin 1 increases the production of endothelin-1 by cultured endothelial cells.

    Masao Yoshizumi;Hiroki Kurihara;Toshisuke Morita;Takahiro Yamashita

  • Overexpression of 15-Lipoxygenase in Vascular Endothelium Accelerates Early Atherosclerosis in LDL Receptor–Deficient Mice

    Dror Harats;Aviv Shaish;Jacob George;Mary Mulkins

Frequent Co-Authors

Yoshio Yazaki
Yoshio Yazaki University of Tokyo
Tomoichiro Asano
Tomoichiro Asano Hiroshima University
Ryozo Nagai
Ryozo Nagai Jichi Medical University
Naomi Nakagata
Naomi Nakagata Kumamoto University
Motonobu Anai
Motonobu Anai University of Tokyo
Hisao Ogawa
Hisao Ogawa Kumamoto University
Masashi Yanagisawa
Masashi Yanagisawa University of Tsukuba
Yasuyoshi Ouchi
Yasuyoshi Ouchi University of Tokyo
Fumimaro Takaku
Fumimaro Takaku University of Tokyo
Giovanni Levi
Giovanni Levi French National Museum of Natural History

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