His primary scientific interests are in Immunology, Virology, Immune system, Interferon and T cell. As part of the same scientific family, David G. Brooks usually focuses on Immunology, concentrating on Cytotoxic T cell and intersecting with Jurkat cells. His Virus and Viral replication study, which is part of a larger body of work in Virology, is frequently linked to Population and Prostratin, bridging the gap between disciplines.
His work in Immune system addresses issues such as Cell activation, which are connected to fields such as Viremia and Genome. As a part of the same scientific study, he usually deals with the Interferon, concentrating on Innate immune system and frequently concerns with Biosynthesis, Cholesterol, Metabolic pathway, Flux and Downregulation and upregulation. David G. Brooks interconnects Phenotype and Immunity in the investigation of issues within T cell.
His primary areas of investigation include Immunology, Virology, Immune system, T cell and Virus. While the research belongs to areas of Immunology, David G. Brooks spends his time largely on the problem of Cytotoxic T cell, intersecting his research to questions surrounding Cell biology. His Virology research is multidisciplinary, incorporating elements of B cell and Interleukin 10.
His Immunotherapy and Acquired immune system study in the realm of Immune system connects with subjects such as Population. The concepts of his T cell study are interwoven with issues in Virus latency, Reprogramming, Cancer research and Immunophenotyping. The study incorporates disciplines such as Innate immune system and Immunosuppression in addition to Interferon.
His primary areas of study are Immunology, Immune system, T cell, Immunotherapy and CD8. David G. Brooks integrates many fields in his works, including Immunology and Chronic lymphedema. His research integrates issues of Immunohistochemistry, Immunosuppression and Mass cytometry in his study of Immune system.
His biological study spans a wide range of topics, including Cancer research, Signal transduction, NFAT and Small interfering RNA. He interconnects Pancreatic tumor, Cytotoxic T cell, Receptor, Spleen and Chronic infection in the investigation of issues within CD8. In his research on the topic of Virus, Hematopoietic stem cell is strongly related with Interferon.
David G. Brooks mainly focuses on Immunotherapy, Immune system, Immunology, T cell and Cytotoxic T cell. His Immunotherapy research incorporates elements of Cancer clinical trial, Clinical trial, Computational biology and Mass cytometry. His work carried out in the field of Immune system brings together such families of science as Proinflammatory cytokine, Flow cytometry, Immunophenotyping and Macrophage polarization.
The Immunology study combines topics in areas such as Intestinal mucosa and Cellular differentiation. His studies deal with areas such as Myeloid, Cancer research, Small interfering RNA, Tumor microenvironment and Transcription factor as well as T cell. His work deals with themes such as Chronic infection, Priming and CD8, which intersect with Cytotoxic T cell.
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Interleukin-10 determines viral clearance or persistence in vivo.
David G Brooks;Matthew J Trifilo;Kurt H Edelmann;Luc Teyton.
Nature Medicine (2006)
Blockade of Chronic Type I Interferon Signaling to Control Persistent LCMV Infection
Elizabeth B. Wilson;Douglas H. Yamada;Heidi Elsaesser;Jonathan Herskovitz.
IL-21 is required to control chronic viral infection.
Heidi Elsaesser;Karsten Sauer;David G. Brooks.
Bobos in Paradise: The New Upper Class and How They Got There
Sterol regulatory element–binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity
Yoko Kidani;Heidi Elsaesser;M Benjamin Hock;M Benjamin Hock;Laurent Vergnes.
Nature Immunology (2013)
Viral persistence redirects CD4 T cell differentiation toward T follicular helper cells
Laura M. Fahey;Elizabeth B. Wilson;Heidi Elsaesser;Chris D. Fistonich.
Journal of Experimental Medicine (2011)
Mitochondria‐derived Reactive Oxygen Species Mediate Blue Light‐induced Death of Retinal Pigment Epithelial Cells¶
Ayala King;Eyal Gottlieb;David G. Brooks;Michael P. Murphy.
Photochemistry and Photobiology (2004)
Cardiolipin provides an essential activating platform for caspase-8 on mitochondria.
Francois Gonzalvez;Zachary T. Schug;Riekelt H. Houtkooper;Elaine D. MacKenzie.
Journal of Cell Biology (2008)
Limiting Cholesterol Biosynthetic Flux Spontaneously Engages Type I IFN Signaling
Autumn G. York;Kevin J. Williams;Joseph P. Argus;Quan D. Zhou.
Type I Interferon in Chronic Virus Infection and Cancer
Laura M. Snell;Tracy L. McGaha;Tracy L. McGaha;David G. Brooks;David G. Brooks.
Trends in Immunology (2017)
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