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Biology and Biochemistry

D-Index
58
Citations
25245
World Ranking
12889
National Ranking
5485

Overview

Dwight Stambolian is a researcher affiliated with the University of Pennsylvania in the United States. Their work primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a noted focus on ophthalmology and related disciplines.

The scientist's subfield contributions include:

  • Ophthalmology
  • Radiology, Nuclear Medicine and Imaging
  • Molecular Biology
  • Epidemiology
  • Cancer Research

Stambolian's research topics cover a range of issues related to eye health and genetics. Main topics of study are:

  • Retinal Diseases and Treatments
  • Retinal Imaging and Analysis
  • Ophthalmology and Visual Impairment Studies
  • Corneal surgery and disorders
  • Glaucoma and retinal disorders
  • Retinal and Optic Conditions
  • Single-cell and spatial transcriptomics

Their recent publications reflect an emphasis on genetics, disease mechanisms, and imaging advances in ophthalmology. Notable recent papers include:

  • "Deep learning enables accurate clustering with batch effect removal in single-cell RNA-seq analysis" (2020), Nature Communications
  • "Evaluation of Shared Genetic Susceptibility to High and Low Myopia and Hyperopia" (2021), JAMA Ophthalmology
  • "Effective refractive error coverage in adults aged 50 years and older: estimates from population-based surveys in 61 countries" (2022), The Lancet Global Health
  • "Genome-wide association meta-analysis of corneal curvature identifies novel loci and shared genetic influences across axial length and refractive error" (2020), Communications Biology
  • "A new polygenic score for refractive error improves detection of children at risk of high myopia but not the prediction of those at risk of myopic macular degeneration" (2023), EBioMedicine

Stambolian frequently publishes in the following venues:

  • Investigative Ophthalmology & Visual Science
  • Nature Communications
  • JAMA Ophthalmology
  • The Lancet Global Health
  • EBioMedicine

Collaboration plays a significant role in their work. Frequent co-authors include:

  • Jonathan L. Haines
  • Margaret A. Pericak-Vance
  • J. Willem L. Tideman
  • Joan E. Bailey-Wilson
  • Jeremy A. Guggenheim

Best Publications

  • Next-generation genotype imputation service and methods.

    Sayantan Das;Lukas Forer;Sebastian Schönherr;Carlo Sidore;Carlo Sidore

  • A reference panel of 64,976 haplotypes for genotype imputation

    Shane McCarthy;Sayantan Das;Warren Kretzschmar;Olivier Delaneau

  • Global Causes of Blindness and Distance Vision Impairment 1990-2020: A Systematic Review and Meta-Analysis

    Seth R Flaxman;Rupert R A Bourne;Serge Resnikoff;Serge Resnikoff;Peter Ackland

  • Magnitude, temporal trends, and projections of the global prevalence of blindness and distance and near vision impairment: a systematic review and meta-analysis

    Rupert R A Bourne;Seth R Flaxman;Tasanee Braithwaite;Maria V Cicinelli

  • A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

    Lars G. Fritsche;Wilmar Igl;Jessica N.Cooke Bailey;Felix Grassmann

  • Seven new loci associated with age-related macular degeneration

    Lars G. Fritsche;Lars G. Fritsche;Wei Chen;Wei Chen;Matthew Schu;Brian L. Yaspan

  • Genetic variants near TIMP3 and high-density lipoprotein–associated loci influence susceptibility to age-related macular degeneration

    Wei Chen;Dwight Stambolian;Albert O. Edwards;Kari E. Branham

  • Age-Related Macular Degeneration: Genetics and Biology Coming Together

    Lars G. Fritsche;Robert N. Fariss;Dwight Stambolian;Gonçalo R. Abecasis

  • Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

    Virginie J M Verhoeven;Pirro G Hysi;Robert Wojciechowski;Robert Wojciechowski;Qiao Fan

  • Transcriptome analysis and molecular signature of human retinal pigment epithelium

    N.V. Strunnikova;A. Maminishkis;J.J. Barb;F. Wang

  • Microphysiological Engineering of Self-Assembled and Perfusable Microvascular Beds for the Production of Vascularized Three-Dimensional Human Microtissues.

    Jungwook Paek;Sunghee E Park;Qiaozhi Lu;Kyu-Tae Park

  • Identification of a rare coding variant in complement 3 associated with age-related macular degeneration

    Xiaowei Zhan;David E. Larson;Chaolong Wang;Chaolong Wang;Daniel C. Koboldt

  • Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error

    Ching-Yu Cheng;Ching-Yu Cheng;Maria Schache;M. Kamran Ikram;M. Kamran Ikram;M. Kamran Ikram;Terri L. Young;Terri L. Young

  • Genomewide Linkage Scan for Myopia Susceptibility Loci among Ashkenazi Jewish Families Shows Evidence of Linkage on Chromosome 22q12

    Dwight Stambolian;Grace Ibay;Lauren Reider;Debra Dana

  • Evidence of association of APOE with age-related macular degeneration: a pooled analysis of 15 studies.

    Gareth J. Mckay;Chris C. Patterson;Usha Chakravarthy;Shilpa Dasari

  • Ribosomal RNA gene sequences and hominoid phylogeny.

    I L Gonzalez;J E Sylvester;T F Smith;D Stambolian

  • Meta-analysis of gene–environment-wide association scans accounting for education level identifies additional loci for refractive error

    Qiao Fan;Qiao Fan;Virginie J M Verhoeven;Robert Wojciechowski;Robert Wojciechowski;Veluchamy A. Barathi

  • Genetics of age-related macular degeneration (AMD).

    Margaret M. DeAngelis;Leah A. Owen;Margaux A. Morrison;Denise J. Morgan

  • Ancestry estimation and control of population stratification for sequence-based association studies.

    Chaolong Wang;Chaolong Wang;Xiaowei Zhan;Jennifer Bragg-Gresham;Hyun Min Kang

  • Complement factor d in age-related macular degeneration

    Chloe M. Stanton;John R.W. Yates;Anneke I. den Hollander;Johanna M. Seddon

Frequent Co-Authors

Joan E. Bailey-Wilson
Joan E. Bailey-Wilson National Institutes of Health
Anand Swaroop
Anand Swaroop National Institutes of Health
Emily Y. Chew
Emily Y. Chew National Institutes of Health
Gonçalo R. Abecasis
Gonçalo R. Abecasis University of Michigan–Ann Arbor
Tien Yin Wong
Tien Yin Wong Tsinghua University
Caroline C W Klaver
Caroline C W Klaver Erasmus University Rotterdam
Margaret A. Pericak-Vance
Margaret A. Pericak-Vance University of Miami
Jie Jin Wang
Jie Jin Wang University of Sydney
Srinivas R. Sadda
Srinivas R. Sadda University of California, Los Angeles
David A. Mackey
David A. Mackey University of Western Australia

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