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Ali A. Ashkar

Ali A. Ashkar

D-Index & Metrics

Immunology

D-Index
61
Citations
12572
World Ranking
3247
National Ranking
81

Overview

Ali A. Ashkar is affiliated with McMaster University in Canada, where their research primarily spans the fields of Immunology and Microbiology as well as Medicine. Their scholarly work includes a focus on Immunology, Oncology, Public Health, Environmental and Occupational Health, Infectious Diseases, and Molecular Biology.

The scientist's main research topics include:

  • Immune Cell Function and Interaction
  • Immune cells in cancer
  • CAR-T cell therapy research
  • T-cell and B-cell Immunology
  • Mosquito-borne diseases and control
  • Immune Response and Inflammation
  • Immunotherapy and Immune Responses

Ali A. Ashkar has contributed to numerous publications, with recent notable papers including:

  • "Metabolic flexibility determines human NK cell functional fate in the tumor microenvironment" (2021), published in Cell Metabolism
  • "AHR signaling is induced by infection with coronaviruses" (2021), published in Nature Communications
  • "Aging and Interferons: Impacts on Inflammation and Viral Disease Outcomes" (2021), published in Cells
  • "Expanded human NK cells armed with CAR uncouple potent anti-tumor activity from off-tumor toxicity against solid tumors" (2021), published in iScience
  • "Asthma exacerbations on benralizumab are largely non-eosinophilic" (2020), published in Allergy

Frequent co-authors in Ali A. Ashkar's work include:

  • Ana L. Portillo
  • Fatemeh Vahedi
  • Emily Feng
  • Elizabeth Balint
  • Sophie M. Poznanski

They have published repeatedly in several key venues, which encompass:

  • The Journal of Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Frontiers in Immunology
  • PLoS Pathogens

Best Publications

  • Interferon γ Contributes to Initiation of Uterine Vascular Modification, Decidual Integrity, and Uterine Natural Killer Cell Maturation during Normal Murine Pregnancy

    Ali A. Ashkar;James P. Di Santo;B. Anne Croy

  • The Dual Nature of Type I and Type II Interferons

    Amanda J. Lee;Ali A. Ashkar

  • Interferon Gamma in Successful Pregnancies

    Shawn P. Murphy;Chandrakant Tayade;Ali A. Ashkar;Kota Hatta

  • Assessment of requirements for IL-15 and IFN regulatory factors in uterine NK cell differentiation and function during pregnancy.

    Ali A. Ashkar;Gordon P. Black;Qingxia Wei;Hong He

  • Progesterone Increases Susceptibility and Decreases Immune Responses to Genital Herpes Infection

    Charu Kaushic;Ali A. Ashkar;Lesley A. Reid;Kenneth L. Rosenthal

  • Interferon-γ Contributes to the Normalcy of Murine Pregnancy

    Ashkar Aa;Croy Ba

  • Uterine natural killer cells: insights into their cellular and molecular biology from mouse modelling.

    BA Croy;H He;S Esadeg;Q Wei

  • Interleukin-15 and natural killer and NKT cells play a critical role in innate protection against genital herpes simplex virus type 2 infection.

    Ali A. Ashkar;Kenneth L. Rosenthal

  • Influenza Infection Leads to Increased Susceptibility to Subsequent Bacterial Superinfection by Impairing NK Cell Responses in the Lung

    Cherrie-Lee Small;Christopher R. Shaler;Sarah McCormick;Mangalakumari Jeyanathan

  • Update on pathways regulating the activation of uterine Natural Killer cells, their interactions with decidual spiral arteries and homing of their precursors to the uterus.

    B.Anne Croy;Souad Esadeg;Sirirak Chantakru;Sirirak Chantakru;Marianne van den Heuvel

  • Metabolic flexibility determines human NK cell functional fate in the tumor microenvironment.

    Sophie M. Poznanski;Kanwaldeep Singh;Tyrah M. Ritchie;Jennifer A. Aguiar

  • Functions of uterine natural killer cells are mediated by interferon gamma production during murine pregnancy.

    A A Ashkar;B A Croy

  • Toll-like Receptor 9, CpG DNA and Innate Immunity

    Ali A Ashkar;Kenneth L Rosenthal

  • Local Delivery of CpG Oligodeoxynucleotides Induces Rapid Changes in the Genital Mucosa and Inhibits Replication, but Not Entry, of Herpes Simplex Virus Type 2

    Ali A. Ashkar;Stefan Bauer;William J. Mitchell;Jeff Vieira

  • Defective NOD2 peptidoglycan sensing promotes diet-induced inflammation, dysbiosis, and insulin resistance

    Emmanuel Denou;Karine Lolmède;Karine Lolmède;Lucile Garidou;Lucile Garidou;Celine Pomie;Celine Pomie

  • Decidual natural killer cells: key regulators of placental development (a review).

    B.Anne Croy;Sirirak Chantakru;Souad Esadeg;Ali A Ashkar

  • Epitope specificity plays a critical role in regulating antibody-dependent cell-mediated cytotoxicity against influenza A virus

    Wenqian He;Gene S. Tan;Caitlin E. Mullarkey;Amanda J. Lee

  • The direct effects of Toll-like receptor ligands on human NK cell cytokine production and cytotoxicity.

    Nicole M. Lauzon;Firoz Mian;Randy MacKenzie;Ali A. Ashkar

  • Toll-Like Receptor (TLR)-3, but Not TLR4, Agonist Protects against Genital Herpes Infection in the Absence of Inflammation Seen with CpG DNA

    Ali A. Ashkar;Xiao-Dan Yao;Navkiran Gill;Dusan Sajic

  • Can Murine Uterine Natural Killer Cells Give Insights Into the Pathogenesis of Preeclampsia

    B A Croy;A A Ashkar;K Minhas;J D Greenwood

  • Responses in the Lung Superinfection by Impairing NK Cell Susceptibility to Subsequent Bacterial Influenza Infection Leads to Increased

    Charu Kaushic;Ali A. Ashkar;Zhou Xing Damjanovic;Earl G. Brown

Frequent Co-Authors

Karen L. Mossman
Karen L. Mossman McMaster University
Kenneth L. Rosenthal
Kenneth L. Rosenthal McMaster University
Carl D. Richards
Carl D. Richards McMaster University
Brian D. Lichty
Brian D. Lichty McMaster University
Zhou Xing
Zhou Xing McMaster University
Manel Jordana
Manel Jordana McMaster University
Jonathan L. Bramson
Jonathan L. Bramson McMaster University
Dean A. Lee
Dean A. Lee Nationwide Children's Hospital
Tony Mazzulli
Tony Mazzulli University Health Network
Michel J. Tremblay
Michel J. Tremblay Université Laval

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