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William S. Dynan

William S. Dynan

D-Index & Metrics

Biology and Biochemistry

D-Index
58
Citations
14622
World Ranking
13026
National Ranking
5552

Overview

William S. Dynan is affiliated with Emory University in the United States. Their research spans multiple disciplines, notably medicine, biochemistry, genetics and molecular biology, and physics and astronomy. A significant portion of their work focuses on pulmonary and respiratory medicine, radiation, molecular biology, oncology, and radiology, nuclear medicine, and imaging.

The scientist's primary research topics include radiation therapy and dosimetry, advanced radiotherapy techniques, radiation detection and scintillator technologies, extracellular vesicles in disease, radiation effects in electronics, DNA repair mechanisms, and PARP inhibition in cancer therapy.

Frequent publication venues for their work include:

  • arXiv (Cornell University)
  • International Journal of Radiation Oncology*Biology*Physics
  • Life Sciences in Space Research
  • Nucleic Acids Research
  • NAR Cancer

Some of the recent papers authored or co-authored by William S. Dynan include:

  • An Integrated Physical Optimization Framework for Proton Stereotactic Body Radiation Therapy FLASH Treatment Planning Allows Dose, Dose Rate, and Linear Energy Transfer Optimization Using Patient-Specific Ridge Filters (2023), published in International Journal of Radiation Oncology*Biology*Physics
  • Exosome-Containing Preparations From Postirradiated Mouse Melanoma Cells Delay Melanoma Growth In Vivo by a Natural Killer Cell-Dependent Mechanism (2020), published in International Journal of Radiation Oncology*Biology*Physics
  • A Novel Inverse Algorithm To Solve the Integrated Optimization of Dose, Dose Rate, and Linear Energy Transfer of Proton FLASH Therapy With Sparse Filters (2023), published in International Journal of Radiation Oncology*Biology*Physics
  • DNA-PK is activated by SIRT2 deacetylation to promote DNA double-strand break repair by non-homologous end joining (2023), published in Nucleic Acids Research
  • Measurement of the time structure of FLASH beams using prompt gamma rays and secondary neutrons as surrogates (2023), published in Physics in Medicine and Biology

William S. Dynan has collaborated frequently with several researchers. Their most common co-authors include:

  • Serdar Charyyev
  • Liyong Lin
  • Ruirui Liu
  • Jun Zhou
  • Xiaofeng Yang

Best Publications

  • The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter

    William S. Dynan;Robert Tjian

  • Control of eukaryotic messenger RNA synthesis by sequence-specific DNA-binding proteins

    William S. Dynan;William S. Dynan;Robert Tjian

  • Isolation of transcription factors that discriminate between different promoters recognized by RNA polymerase II

    William S. Dynan;Robert Tjian

  • Multiple specific contacts between a mammalian transcription factor and its cognate promoters

    David Gidoni;William S. Dynan;Robert Tjian

  • Interaction of Ku protein and DNA-dependent protein kinase catalytic subunit with nucleic acids

    William S. Dynan;Sunghan Yoo

  • Transcription factor Sp1 recognizes a DNA sequence in the mouse dihydrofolate reductase promoter

    William S. Dynan;William S. Dynan;Shelley Sazer;Robert Tjian;Robert T. Schimke

  • Measurement of the binding of transcription factor Sp1 to a single GC box recognition sequence

    John Letovsky;William S. Dynan

  • Models for Evaluating Agents Intended for the Prophylaxis, Mitigation and Treatment of Radiation Injuries Report of an NCI Workshop, December 3–4, 2003

    Helen B. Stone;John E. Moulder;C. Norman Coleman;K. Kian Ang

  • Geometry of a complex formed by double strand break repair proteins at a single DNA end: Recruitment of DNA-PKcs induces inward translocation of Ku protein

    Sunghan Yoo;William S. Dynan

  • Purification and characterization of a template-associated protein kinase that phosphorylates RNA polymerase II.

    Arik Dvir;L. Y. Stein;B. L. Calore;W. S. Dynan

  • Reconstitution of the mammalian DNA double-strand break end-joining reaction reveals a requirement for an Mre11/Rad50/NBS1-containing fraction

    Juren Huang;William S. Dynan

  • Editorial: NAR Surveys the Past, Present and Future of Restriction Endonucleases

    William Dynan;Keith Fox;Barry Stoddard

  • SAMHD1 Promotes DNA End Resection to Facilitate DNA Repair by Homologous Recombination.

    Waaqo Daddacha;Allyson E. Koyen;Amanda J. Bastien;Pamela Sara E. Head

  • Identification of the Polypyrimidine Tract Binding Protein-associated Splicing Factor·p54(nrb) Complex as a Candidate DNA Double-strand Break Rejoining Factor

    Catherine L. Bladen;Durga Udayakumar;Yoshihiko Takeda;William S. Dynan

  • Ku Proteins Join DNA Fragments as Shown by Atomic Force Microscopy

    Dalong Pang;Sunghan Yoo;William S. Dynan;Mira Jung

  • Purification and characterization of wheat germ DNA topoisomerase I (nicking-closing enzyme).

    W S Dynan;J J Jendrisak;D A Hager;R R Burgess

  • Analysis of the phosphorylation of human heat shock transcription factor-1 by MAP kinase family members.

    Jynho Kim;Arsenio Nueda;Yong Hong Meng;William S. Dynan

  • Simian virus 40 major late promoter: a novel tripartite structure that includes intragenic sequences.

    D E Ayer;W S Dynan

  • Photocross-linking of an Oriented DNA Repair Complex Ku BOUND AT A SINGLE DNA END

    Sunghan Yoo;Amy Kimzey;William S. Dynan

  • DNA Ligase IV and XRCC4 Form a Stable Mixed Tetramer That Functions Synergistically with Other Repair Factors in a Cell-free End-joining System

    Kyung Jong Lee;Juren Huang;Yoshihiko Takeda;William S. Dynan

Frequent Co-Authors

John K. Cowell
John K. Cowell Augusta University
John A. Hardin
John A. Hardin Albert Einstein College of Medicine
Richard R. Burgess
Richard R. Burgess University of Wisconsin–Madison
William H. McBride
William H. McBride University of California, Los Angeles
Robert H. Schiestl
Robert H. Schiestl University of California, Los Angeles
Gang Bao
Gang Bao Rice University
James R. Goldenring
James R. Goldenring Vanderbilt University
David E. Hinton
David E. Hinton Duke University
David Roth
David Roth University of Miami
Matthew H. Porteus
Matthew H. Porteus Stanford University

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