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Molecular Biology

D-Index
41
Citations
10946
World Ranking
3046
National Ranking
1443

Overview

Paul D. Kaufman is affiliated with the University of Massachusetts Chan Medical School in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a significant emphasis on molecular biology as a subfield. Additional areas of study include plant science, oncology, physiology, and cell biology.

Their work covers several main topics in contemporary life sciences. These include RNA research and splicing, genomics and chromatin dynamics, RNA modifications and cancer, chromosomal and genetic variations, DNA repair mechanisms, RNA regulation and disease, and RNA and protein synthesis mechanisms.

Paul D. Kaufman has published extensively, with recent articles appearing in various scientific journals. Notable papers include:

  • "Close to the edge: Heterochromatin at the nucleolar and nuclear peripheries" (2020) published in Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
  • "Distinct features of nucleolus-associated domains in mouse embryonic stem cells" (2020) published in Chromosoma
  • "The chromatin-binding domain of Ki-67 together with p53 protects human chromosomes from mitotic damage" (2021) published in Proceedings of the National Academy of Sciences
  • "Nucleolus and centromere Tyramide Signal Amplification-Seq reveals variable localization of heterochromatin in different cell types" (2024) published in Communications Biology
  • "Nucleolus and centromere TSA-Seq reveals variable localization of heterochromatin in different cell types" (2023) published in bioRxiv (Cold Spring Harbor Laboratory)

The scientist frequently collaborates with several coauthors, including Valentina Salsi, Francesca Losi, Rossella Tupler, Lihua Julie Zhu, and Aizhan Bizhanova.

Paul D. Kaufman's research outputs are often published in a select group of venues. These include bioRxiv (Cold Spring Harbor Laboratory), Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, Communications Biology, Chromosoma, and Proceedings of the National Academy of Sciences. The bioRxiv repository has served as the venue for four of their publications, indicating active engagement with preprint dissemination.

Best Publications

  • A versatile viral system for expression and depletion of proteins in mammalian cells.

    Eric Campeau;Victoria E. Ruhl;Francis Rodier;Francis Rodier;Corey Lewis Smith

  • Nucleosome assembly by a complex of CAF-1 and acetylated histones H3/H4.

    Alain Verreault;Paul D Kaufman;Ryuji Kobayashi;Bruce Stillman

  • Formation of MacroH2A-Containing Senescence-Associated Heterochromatin Foci and Senescence Driven by ASF1a and HIRA

    Rugang Zhang;Maxim V. Poustovoitov;Maxim V. Poustovoitov;Xiaofen Ye;Hidelita A. Santos

  • Ki-67: more than a proliferation marker.

    Xiaoming Sun;Paul D. Kaufman

  • The p150 and p60 Subunits of Chromatin Assembly Factor I: A Molecular Link between Newly Synthesized Histones and DNA Replication

    Paul D. Kaufman;Ryuji Kobayashi;Naama Kessler;Bruce Stillman

  • Ultraviolet radiation sensitivity and reduction of telomeric silencing in Saccharomyces cerevisiae cells lacking chromatin assembly factor-I.

    Paul D. Kaufman;Ryuji Kobayashi;Bruce Stillman

  • Nucleosomal DNA regulates the core-histone-binding subunit of the human Hat1 acetyltransferase

    Alain Verreault;Paul D. Kaufman;Ryuji Kobayashi;Bruce Stillman

  • Chromatin Assembly Coupled to DNA Repair: A New Role for Chromatin Assembly Factor I

    Pierre-Henri L Gaillard;Emmanuelle M.-D Martini;Paul D Kaufman;Bruce Stillman

  • Defective S Phase Chromatin Assembly Causes DNA Damage, Activation of the S Phase Checkpoint, and S Phase Arrest

    Xiaofen Ye;Alexa A Franco;Alexa A Franco;Hidelita Santos;David M Nelson

  • Yeast histone deposition protein Asf1p requires Hir proteins and PCNA for heterochromatic silencing

    Judith A. Sharp;Erik T. Fouts;Denise C. Krawitz;Paul D. Kaufman

  • Histone chaperone Asf1 is required for histone H3 lysine 56 acetylation, a modification associated with S phase in mitosis and meiosis

    J. Recht;T. Tsubota;J. C. Tanny;R. L. Diaz

  • Replication-independent histone deposition by the HIR complex and Asf1.

    Erin M. Green;Andrew J. Antczak;Aaron O. Bailey;Alexa A. Franco

  • Defects in SPT16 or POB3 (yFACT) in saccharomyces cerevisiae cause dependence on the Hir/Hpc pathway: Polymerase passage may degrade chromatin structure

    Tim Formosa;Susan Ruone;Melissa D. Adams;Aileen E. Olsen

  • Hir proteins are required for position-dependent gene silencing in Saccharomyces cerevisiae in the absence of chromatin assembly factor I.

    Paul D. Kaufman;Jennifer L. Cohen;Mary Ann Osley

  • Chromatin Assembly Factor I Mutants Defective for PCNA Binding Require Asf1/Hir Proteins for Silencing

    Denise C. Krawitz;Tamar Kama;Paul D. Kaufman

  • P element transposition in vitro proceeds by a cut-and-paste mechanism and uses GTP as a cofactor

    Paul D. Kaufman;Donald C. Rio

  • Structure and Function of the Conserved Core of Histone Deposition Protein Asf1

    Sally M Daganzo;Jan P Erzberger;Wendy M Lam;Wendy M Lam;Emmanuel Skordalakes

  • Drosophila P element transposase recognizes internal P element DNA sequences.

    Paul D. Kaufman;Rhonda F. Doll;Donald C. Rio

  • Cell Cycle- and Chaperone-Mediated Regulation of H3K56ac Incorporation in Yeast

    Tommy Kaplan;Chih Long Liu;Judith A Erkmann;John Holik

  • Chromatin assembly factor I and Hir proteins contribute to building functional kinetochores in S. cerevisiae.

    Judith A. Sharp;Alexa A. Franco;Mary Ann Osley;Paul D. Kaufman

Frequent Co-Authors

Lihua Julie Zhu
Lihua Julie Zhu University of Massachusetts Chan Medical School
Bruce Stillman
Bruce Stillman Cold Spring Harbor Laboratory
Oliver J. Rando
Oliver J. Rando University of Massachusetts Chan Medical School
James M. Berger
James M. Berger Johns Hopkins University
Nir Friedman
Nir Friedman Weizmann Institute of Science
Ryuji Kobayashi
Ryuji Kobayashi The University of Texas MD Anderson Cancer Center
John M. Denu
John M. Denu University of Wisconsin–Madison
Paul M. Thomas
Paul M. Thomas Northwestern University
Neil L. Kelleher
Neil L. Kelleher Northwestern University
Peter D. Adams
Peter D. Adams Sanford Burnham Prebys Medical Discovery Institute

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