World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
50
Citations
22324
World Ranking
17394
National Ranking
7147

Research.com Recognitions

  • 2017 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Jessica K. Tyler is affiliated with Cornell University in the United States and has made contributions across multiple topics within biochemistry, genetics, and molecular biology. Their body of work spans research published predominantly in the areas of molecular biology, oncology, genetics, immunology, and aging.

The scientist's research topics cover a range of specialized areas, including:

  • DNA Repair Mechanisms
  • CRISPR and Genetic Engineering
  • Genomics and Chromatin Dynamics
  • PARP inhibition in cancer therapy
  • Metabolism, Diabetes, and Cancer
  • Fungal and yeast genetics research
  • RNA and protein synthesis mechanisms

Their frequent coauthors reflect collaborative efforts in their research projects and include:

  • Barry P. Sleckman
  • Bo-Ruei Chen
  • Faith Fowler
  • Nina Arslanovic
  • Zulong Chen

Jessica K. Tyler's work has been published in a variety of venues with multiple publications in each. Regular publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • eLife
  • Human Immunology
  • DNA repair
  • Frontiers in Cell and Developmental Biology

Representative recent papers demonstrate the range and focus of their research. These include:

  • "Positive Reinforcing Mechanisms between GPR120 and PPARγ Modulate Insulin Sensitivity" published in 2020 in Cell Metabolism
  • "The Chromatin Landscape Channels DNA Double-Strand Breaks to Distinct Repair Pathways" published in 2022 in Frontiers in Cell and Developmental Biology
  • "Selenium supplementation inhibits IGF-1 signaling and confers methionine restriction-like healthspan benefits to mice" published in 2021 in eLife
  • "Chaperoning histones at the DNA repair dance" published in 2021 in DNA repair
  • "Sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) activity is required for V(D)J recombination" published in 2021 in The Journal of Experimental Medicine

The scientist's work in biochemistry, genetics, and molecular biology has been recognized in 2017 with the award of Fellow of the American Association for the Advancement of Science (AAAS).

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • CBP/p300-mediated acetylation of histone H3 on lysine 56.

    Chandrima Das;M. Scott Lucia;Kirk C. Hansen;Jessica K. Tyler

  • Epigenetics and aging.

    Sangita Pal;Jessica K. Tyler

  • The RCAF complex mediates chromatin assembly during DNA replication and repair

    Jessica K. Tyler;Christopher R. Adams;Shaw Ree Chen;Shaw Ree Chen;Ryuji Kobayashi

  • Structural Basis for the Histone Chaperone Activity of Asf1

    Christine M. English;Melissa W. Adkins;Joshua J. Carson;Mair E.A. Churchill

  • Acetylated Lysine 56 on Histone H3 Drives Chromatin Assembly after Repair and Signals for the Completion of Repair

    Chin Chuan Chen;Joshua J. Carson;Jason Feser;Beth Tamburini

  • Chaperoning Histones during DNA Replication and Repair

    Monica Ransom;Briana K. Dennehey;Jessica K. Tyler

  • Elevated Histone Expression Promotes Life Span Extension

    Jason Feser;David Truong;Chandrima Das;Joshua J. Carson

  • Chromatin Disassembly Mediated by the Histone Chaperone Asf1 Is Essential for Transcriptional Activation of the Yeast PHO5 and PHO8 Genes

    Melissa W. Adkins;Susan R. Howar;Jessica K. Tyler

  • DANPOS: dynamic analysis of nucleosome position and occupancy by sequencing.

    Kaifu Chen;Yuanxin Xi;Xuewen Pan;Zhaoyu Li

  • Localized histone acetylation and deacetylation triggered by the homologous recombination pathway of double-strand DNA repair.

    Beth A. Tamburini;Jessica K. Tyler

  • Nucleosome loss leads to global transcriptional up-regulation and genomic instability during yeast aging

    Zheng Hu;Kaifu Chen;Zheng Xia;Myrriah Chavez;Myrriah Chavez

  • The “Dark Side” of Chromatin Remodeling: Repressive Effects on Transcription

    Jessica K Tyler;James T Kadonaga

  • Interaction between the Drosophila CAF-1 and ASF1 Chromatin Assembly Factors

    Jessica K. Tyler;Kimberly A. Collins;Jayashree Prasad-Sinha;Elizabeth Amiott

  • Acetylation in the globular core of histone H3 on lysine-56 promotes chromatin disassembly during transcriptional activation

    Stephanie K. Williams;David Truong;Jessica K. Tyler

  • Transcriptional Activators Are Dispensable for Transcription in the Absence of Spt6-Mediated Chromatin Reassembly of Promoter Regions

    Melissa W. Adkins;Jessica K. Tyler

  • Chromatin assembly. Cooperation between histone chaperones and ATP-dependent nucleosome remodeling machines.

    Jessica K. Tyler

  • The histone shuffle: histone chaperones in an energetic dance

    Chandrima Das;Jessica K. Tyler;Mair E.A. Churchill

  • Chromatin structure as a mediator of aging

    Jason Feser;Jessica Tyler

  • The Overlooked Fact: Fundamental Need for Spike-In Control for Virtually All Genome-Wide Analyses.

    Kaifu Chen;Zheng Hu;Zheng Xia;Dongyu Zhao;Dongyu Zhao

Frequent Co-Authors

Mair E. A. Churchill
Mair E. A. Churchill University of Colorado Denver
James T. Kadonaga
James T. Kadonaga University of California, San Diego
Barry P. Sleckman
Barry P. Sleckman University of Alabama at Birmingham
Ryuji Kobayashi
Ryuji Kobayashi The University of Texas MD Anderson Cancer Center
Kirk C. Hansen
Kirk C. Hansen University of Colorado Anschutz Medical Campus
Roger D. Everett
Roger D. Everett University of Glasgow
Tej K. Pandita
Tej K. Pandita Houston Methodist
Vladimir N. Uversky
Vladimir N. Uversky University of South Florida
Travis Nemkov
Travis Nemkov University of Colorado Denver
Alan J. Tackett
Alan J. Tackett University of Arkansas for Medical Sciences

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