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Chemistry

D-Index
55
Citations
11496
World Ranking
12075
National Ranking
96

Research.com Recognitions

  • 1995 - Fellow of American Physical Society (APS) Citation For pioneering contributions to the application of techniques of theoretical atomic and molecular physics to formation of muonic atoms and molecules, their interactions with normal species, and muoncatalyzed fusion

Overview

Jack S. Cohen is affiliated with Ben-Gurion University of the Negev in Israel and specializes in biochemical and molecular biology research. Their scholarly contributions are primarily situated within the fields of Biochemistry, Genetics and Molecular Biology, with focused subfields including Molecular Biology, Cancer Research, Radiology, Nuclear Medicine and Imaging, Materials Chemistry, and Biomaterials.

The main topics addressed in Cohen's research include:

  • DNA and Nucleic Acid Chemistry
  • RNA and protein synthesis mechanisms
  • CRISPR and Genetic Engineering
  • Metabolomics and Mass Spectrometry Studies
  • Cancer, Lipids, and Metabolism
  • Mitochondrial Function and Pathology
  • Advanced biosensing and bioanalysis techniques

Cohen has published extensively, with a selection of recent papers that reflect interests in antisense oligonucleotides, phospholipid metabolism, and cancer biology, among others:

  • "History of Research on Antisense Oligonucleotide Analogs," 2021, Substantia
  • "History of Research on Phospholipid Metabolism and Applications to the Detection, Diagnosis, and Treatment of Cancer," 2022, Substantia
  • "Potential Use of Multiple Antisense Oligonucleotide Analogs for Cancer Prevention and Therapy," 2024, Substantia

In addition to Cohen's publications, there are related works in collaboration with coauthors, contributing to areas such as molecular dynamics simulations and chemically modified nucleic acids. Frequent coauthors include Barak Akabayov, Rodrigo Galindo-Murillo, Peter F. Daly, and Silvio Aime.

Cohen's research has been published in several venues with multiple articles appearing in the journal Substantia. Other publication venues include Molecular Therapy - Nucleic Acids and NAR Genomics and Bioinformatics.

The scientist was recognized as a Fellow of the American Physical Society (APS) in 1995 for pioneering contributions involving theoretical atomic and molecular physics, specifically in muonic atoms, molecules, and muon-catalyzed fusion.

Best Publications

  • Characterization of oligonucleotide transport into living cells

    S L Loke;C A Stein;X H Zhang;K Mori

  • Oligodeoxynucleotides: Antisense Inhibitors of Gene Expression

    Mridul K. Ghosh;Jack S. Cohen

  • Physicochemical properties of phosphorothioate oligodeoxynucleotides.

    Unknown

  • Regulation of viral expression of human immunodeficiency virus in vitro by an antisense phosphorothioate oligodeoxynucleotide against rev (art/trs) in chronically infected cells.

    Makoto Matsukura;Gerald Zon;Kazuo Shinozuka;Marjorie Robert-Guroff

  • Phospholipid metabolism in cancer cells monitored by 31P NMR spectroscopy.

    P F Daly;R C Lyon;P J Faustino;J S Cohen

  • Comparative inhibition of rabbit globin mRNA translation by modified antisense oligodeoxynucleotides

    C. Cazenave;C.A. Stein;N. Loreau;N.T. Thuong

  • Gradient-enhanced heteronuclear correlation spectroscopy: Theory and experimental aspects

    Jesús Ruiz-Cabello;Geerten W. Vuister;Chrit T.W. Moonen;Peter van Gelderen

  • Phospholipid metabolites as indicators of cancer cell function.

    Jesús Ruiz-Cabello;Jack S. Cohen

  • Comparison of single-shot localization methods (STEAM and PRESS) for in vivo proton NMR spectroscopy.

    Chrit T. W. Moonen;Markus Von Kienlin;Peter C. M. Van Zijl;Jack Cohen

  • Complete separation of intracellular and extracellular information in NMR spectra of perfused cells by diffusion-weighted spectroscopy.

    P.C.M. Van Zijl;C.T.W. Moonen;P. Faustino;J. Pekar

  • Nuclear magnetic resonance and neutron diffraction studies of the complex of ribonuclease A with uridine vanadate, a transition-state analogue.

    Babul Borah;Chi Wan Chen;William Egan;Maria Miller

  • Paramagnetic metalloporphyrins as potential contrast agents in NMR imaging

    Chi-wan Chen;Jack S. Cohen;Charles E. Myers;Miriam Sohn

  • THE MECHANISM OF ACTION OF RIBONUCLEASE

    Gordon C. K. Roberts;Edward A. Dennis;Donella H. Meadows;Jack S. Cohen

  • Effects of Sequence of Thioated Oligonucleotides on Cultured Human Mammary Epithelial Cells

    Paul Yaswen;Martha R. Stampfer;Krishna Ghosh;Jack S. Cohen

  • Mathematical models for interacting groups in nuclear magnetic resonance titration curves.

    Richard I. Shrager;Jack S. Cohen;Stephen R. Heller;David H. Sachs

  • Structural studies on the sialic acid polysaccharide antigen of Escherichia coli strain Bos-12.

    William Egan;Teh-Yung Liu;Donna Dorow;Jack S. Cohen

  • Tissue distribution and stability of metalloporphyrin MRI contrast agents.

    R. C. Lyon;P. J. Faustino;J. S. Cohen;A. Katz

  • Nuclear magnetic resonance studies of the structure and binding sites of enzymes. I. Histidine residues.

    Donella H. Meadows;John L. Markley;Jack S. Cohen;Oleg Jardetzky

  • Internal pH and state of ATP in adrenergic chromaffin granules determined by 31P nuclear magnetic resonance spectroscopy.

    H B Pollard;H Shindo;C E Creutz;C J Pazoles

  • Nuclear magnetic resonance titration curves of histidine ring protons. I. Influence of neighboring charged groups.

    David H. Sachs;Alan N. Schechter;Jack S. Cohen

  • Oligonucleotides as therapeutic agents.

    Jack S. Cohen

  • Continuous perfusion of mammalian cells embedded in agarose gel threads

    David L. Foxall;Jack S. Cohen;James B. Mitchell

Frequent Co-Authors

Alan N. Schechter
Alan N. Schechter National Institute of Diabetes and Digestive and Kidney Diseases
John H. Griffin
John H. Griffin Scripps Research Institute
Gerald Zon
Gerald Zon TriLink BioTechnologies (United States)
Chrit T. W. Moonen
Chrit T. W. Moonen Utrecht University
Ettore Appella
Ettore Appella National Institutes of Health
David H. Sachs
David H. Sachs Columbia University
Yechezkel Barenholz
Yechezkel Barenholz Hebrew University of Jerusalem
Sabita Roy
Sabita Roy University of Miami
Samuel Broder
Samuel Broder Precision BioSciences
Hiroaki Mitsuya
Hiroaki Mitsuya Kumamoto University

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