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Biology and Biochemistry

D-Index
48
Citations
8386
World Ranking
18386
National Ranking
7507

Overview

David A. Stein is affiliated with Oregon State University in the United States. Their research primarily focuses on medicine, with notable contributions to biochemistry, genetics, and molecular biology.

Their work spans several subfields including infectious diseases, epidemiology, molecular biology, immunology, and genetics. Key research topics addressed by Stein include SARS-CoV-2 and COVID-19 research, interferon and immune responses, influenza virus research studies, RNA interference and gene delivery, respiratory viral infections, COVID-19 clinical research, and mosquito-borne diseases and control.

Stein has published extensively in multiple venues. Frequent outlets for their publications include:

  • Journal of Virology
  • The American Journal of Gastroenterology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • The FASEB Journal
  • Life Science Alliance

Notable recent papers by David A. Stein include:

  • TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells, 2020, Life Science Alliance
  • TMPRSS2 and furin are both essential for proteolytic activation and spread of SARS-CoV-2 in human airway epithelial cells and provide promising drug targets, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • Restriction factor compendium for influenza A virus reveals a mechanism for evasion of autophagy, 2021, Nature Microbiology
  • Hemagglutinins of Avian Influenza Viruses Are Proteolytically Activated by TMPRSS2 in Human and Murine Airway Cells, 2021, Journal of Virology
  • Inhibition of SARS-CoV-2 in Vero cell cultures by peptide-conjugated morpholino oligomers, 2020, Journal of Antimicrobial Chemotherapy

David A. Stein has collaborated frequently with several researchers, including:

  • Hong M. Moulton
  • Eva Böttcher-Friebertshäuser
  • Dorothea Bestle
  • Hannah Limburg
  • Torsten Steinmetzer

Best Publications

  • Meta- and Orthogonal Integration of Influenza “OMICs” Data Defines a Role for UBR4 in Virus Budding

    Shashank Tripathi;Marie O. Pohl;Yingyao Zhou;Ariel Rodriguez-Frandsen

  • TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells.

    Dorothea Bestle;Miriam Ruth Heindl;Hannah Limburg;Thuy van Lam van

  • Morpholino and Phosphorothioate Antisense Oligomers Compared in Cell-Free and In-Cell Systems

    James Summerton;David Stein;Sung Ben Huang;Paula Matthews

  • A Specificity Comparison of Four Antisense Types: Morpholino, 2′-O-Methyl RNA, DNA, and Phosphorothioate DNA

    David Stein;Ernest Foster;Sung-Ben Huang;Dwight Weller

  • Cell penetrating peptide conjugates of steric block oligonucleotides

    Bernard Lebleu;Hong M. Moulton;Rachida Abes;Gabriela D. Ivanova

  • Inhibition of Flavivirus Infections by Antisense Oligomers Specifically Suppressing Viral Translation and RNA Replication

    Tia S. Deas;Iwona Binduga-Gajewska;Mark Tilgner;Ping Ren

  • Phase Transitions Drive the Formation of Vesicular Stomatitis Virus Replication Compartments.

    Bianca S. Heinrich;Zoltan Maliga;Zoltan Maliga;David A. Stein;Anthony A. Hyman

  • Gene-Specific Countermeasures against Ebola Virus Based on Antisense Phosphorodiamidate Morpholino Oligomers

    Kelly L Warfield;Dana L Swenson;Gene G Olinger;Donald K Nichols

  • Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKε kinase-mediated antiviral response.

    Ricardo Rajsbaum;Gijs A. Versteeg;Gijs A. Versteeg;Sonja Schmid;Ana M. Maestre

  • Inhibition of dengue virus translation and RNA synthesis by a morpholino oligomer targeted to the top of the terminal 3' stem-loop structure.

    Katherine Lynn Holden;David A. Stein;Theodore C. Pierson;Asim A. Ahmed

  • TMPRSS2 Is the Major Activating Protease of Influenza A Virus in Primary Human Airway Cells and Influenza B Virus in Human Type II Pneumocytes.

    Hannah Limburg;Anne Harbig;Dorothea Bestle;David A. Stein

  • VP35 Knockdown Inhibits Ebola Virus Amplification and Protects against Lethal Infection in Mice

    Sven Enterlein;Kelly L. Warfield;Dana L. Swenson;David A. Stein

  • Severe Acute Respiratory Syndrome Coronavirus Triggers Apoptosis via Protein Kinase R but Is Resistant to Its Antiviral Activity

    Verena Krähling;David A. Stein;Martin Spiegel;Friedemann Weber

  • Inhibition of Dengue Virus Serotypes 1 to 4 in Vero Cell Cultures with Morpholino Oligomers

    Richard M. Kinney;Claire Y.-H. Huang;Becky C. Rose;Andrew D. Kroeker

  • A Simple Method for Delivering Morpholino Antisense Oligos into the Cytoplasm of Cells

    Michael Partridge;Alexandra Vincent;Paula Matthews;John Puma

  • c-Myc antisense limits rat liver regeneration and indicates role for c-Myc in regulating cytochrome P-450 3A activity.

    Vikram Arora;Derek C. Knapp;Barbara L. Smith;Mary L. Statdfield

  • Inhibition of Gene Expression in Escherichia coli by Antisense Phosphorodiamidate Morpholino Oligomers

    B. L. Geller;J. D. Deere;D. A. Stein;A. D. Kroeker

  • Inhibition, Escape, and Attenuated Growth of Severe Acute Respiratory Syndrome Coronavirus Treated with Antisense Morpholino Oligomers

    Benjamin W. Neuman;David A. Stein;Andrew D. Kroeker;Michael J. Churchill

  • Inhibition of Influenza Virus Infection in Human Airway Cell Cultures by an Antisense Peptide-Conjugated Morpholino Oligomer Targeting the Hemagglutinin-Activating Protease TMPRSS2

    Eva Böttcher-Friebertshäuser;David A. Stein;Hans-Dieter Klenk;Wolfgang Garten

  • A novel antisense inhibitor of MMP-9 attenuates angiogenesis, human prostate cancer cell invasion and tumorigenicity

    Carla A London;Harmanjatinder S Sekhon;Vikram Arora;David A Stein

Frequent Co-Authors

Patrick L. Iversen
Patrick L. Iversen Oregon State University
Pei-Yong Shi
Pei-Yong Shi GlaxoSmithKline (United Kingdom)
David O. Matson
David O. Matson Eastern Virginia Medical School
Michael J. Buchmeier
Michael J. Buchmeier University of California, Irvine
Laura D. Kramer
Laura D. Kramer University at Albany, State University of New York
Hans-Dieter Klenk
Hans-Dieter Klenk Philipp University of Marburg
Adolfo García-Sastre
Adolfo García-Sastre Icahn School of Medicine at Mount Sinai
Nevan J. Krogan
Nevan J. Krogan University of California, San Francisco
Elke Mühlberger
Elke Mühlberger Boston University
Kelly L. Warfield
Kelly L. Warfield United States Department of the Army

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