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Biology and Biochemistry

D-Index
58
Citations
11628
World Ranking
13215
National Ranking
5629

Overview

Jeffrey T. Billheimer is affiliated with the University of Pennsylvania in the United States. Their research primarily focuses on medicine and biochemistry, genetics, and molecular biology, with significant contributions to endocrinology, diabetes and metabolism, surgery, molecular biology, cardiology and cardiovascular medicine, and biochemistry.

Their work addresses multiple topics related to metabolic and cardiovascular health including:

  • Diabetes, cardiovascular risks, and lipoproteins
  • Lipid metabolism and biosynthesis
  • Cholesterol and lipid metabolism
  • Menopause: health impacts and treatments
  • Lipoproteins and cardiovascular health
  • Endoplasmic reticulum stress and disease
  • Adipokines, inflammation, and metabolic diseases

Jeffrey T. Billheimer has published in various venues, frequently contributing to:

  • The Journal of Clinical Endocrinology & Metabolism
  • Circulation
  • PLoS Genetics
  • Journal of Alzheimer s Disease
  • Alzheimer s Research & Therapy

Recent papers by Billheimer include:

  • Endothelial lipase mediates efficient lipolysis of triglyceride-rich lipoproteins, 2021, PLoS Genetics
  • Correlates and Predictors of Cerebrospinal Fluid Cholesterol Efflux Capacity from Neural Cells, a Family of Biomarkers for Cholesterol Epidemiology in Alzheimer's Disease, 2020, Journal of Alzheimer s Disease
  • ApoJ/Clusterin concentrations are determinants of cerebrospinal fluid cholesterol efflux capacity and reduced levels are associated with Alzheimer's disease, 2022, Alzheimer s Research & Therapy
  • Specificity of ABCA7-mediated cell lipid efflux, 2022, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
  • A missense variant in human perilipin 2 (PLIN2 Ser251Pro) reduces hepatic steatosis in mice, 2023, JHEP Reports

The scientist frequently collaborates with a core group of coauthors, including:

  • Daniel J. Rader
  • Maria M. Brooks
  • Trevor J. Orchard
  • Samar R. El Khoudary
  • Dan McConnell

Best Publications

  • The role of reverse cholesterol transport in animals and humans and relationship to atherosclerosis.

    Daniel J. Rader;Daniel J. Rader;Eric T. Alexander;Eric T. Alexander;Ginny L. Weibel;Jeffrey Billheimer

  • Macrophage ABCA1 and ABCG1, but not SR-BI, promote macrophage reverse cholesterol transport in vivo

    Xun Wang;Heidi L. Collins;Mollie Ranalletta;Ilia V. Fuki

  • Pharmacological Activation of Liver X Receptors Promotes Reverse Cholesterol Transport In Vivo

    Snehal U. Naik;Xun Wang;Jaqueline S. Da Silva;Michael Jaye

  • Characterization of Two Human Genes Encoding Acyl Coenzyme A:Cholesterol Acyltransferase-related Enzymes

    Peter Oelkers;Ajay Behari;Debra Cromley;Jeffrey T. Billheimer

  • Hepatic expression of scavenger receptor class B type I (SR-BI) is a positive regulator of macrophage reverse cholesterol transport in vivo

    YuZhen Zhang;Jaqueline R. Da Silva;Muredach Reilly;Jeffrey T. Billheimer

  • Inflammation Impairs Reverse Cholesterol Transport In Vivo

    Fiona C. McGillicuddy;Margarita de la Llera Moya;Christine C. Hinkle;Michelle R. Joshi

  • The roles of different pathways in the release of cholesterol from macrophages.

    Maria Pia Adorni;Francesca Zimetti;Jeffrey T. Billheimer;Nan Wang

  • The DGA1 Gene Determines a Second Triglyceride Synthetic Pathway in Yeast

    Peter Oelkers;Debra Cromley;Mahajabeen Padamsee;Jeffrey T. Billheimer

  • Determining hepatic triglyceride production in mice: comparison of poloxamer 407 with Triton WR-1339

    John S. Millar;Debra A. Cromley;Mary G. McCoy;Daniel J. Rader

  • A lecithin cholesterol acyltransferase-like gene mediates diacylglycerol esterification in yeast.

    Peter Oelkers;Arthur Tinkelenberg;Naz Erdeniz;Debra Cromley

  • Lith1, a major gene affecting cholesterol gallstone formation among inbred strains of mice

    Bhupinder Khanuja;Yin-Chai Cheah;Mark Hunt;Patsy M. Nishina

  • Steroidogenic acute regulatory protein (StAR) is a sterol transfer protein.

    Caleb B. Kallen;Jeffrey T. Billheimer;Scott A. Summers;Steven E. Stayrook

  • Expression of Cholesteryl Ester Transfer Protein in Mice Promotes Macrophage Reverse Cholesterol Transport

    Hiroyuki Tanigawa;Jeffrey T. Billheimer;Jun-ichiro Tohyama;YuZhen Zhang

  • STEROL CARRIER PROTEIN-2, A NEW FATTY ACYL COENZYME A-BINDING PROTEIN

    Andrey Frolov;Tae-Hyeon Cho;Jeffrey T. Billheimer;Friedhelm Schroeder

  • Cloning and expression of a cDNA encoding human sterol carrier protein 2.

    Ritsu Yamamoto;Caleb B. Kallen;Gbolagade O. Babalola;Hannah Rennert

  • Probing the ligand binding sites of fatty acid and sterol carrier proteins: effects of ethanol.

    Schroeder F;Myers-Payne Sc;Billheimer Jt;Wood Wg

  • Knockdown of acyl-CoA:diacylglycerol acyltransferase 2 with antisense oligonucleotide reduces VLDL TG and ApoB secretion in mice.

    Ying Liu;John S. Millar;Debra A. Cromley;Mark Graham

  • Identification of two novel human acyl-CoA wax alcohol acyltransferases: members of the diacylglycerol acyltransferase 2 (DGAT2) gene superfamily.

    Aaron R. Turkish;Annette L. Henneberry;Debra Cromley;Mahajabeen Padamsee

  • The sterol substrate specificity of acyl CoA: :cholesterol acyltransferase from rat liver.

    Deebeanne M. Tavani;William R. Nes;Jeffrey T. Billheimer

  • Spontaneous and Protein-mediated Sterol Transfer between Intracellular Membranes

    Andrey Frolov;Judith K. Woodford;Eric J. Murphy;Jeffrey T. Billheimer

Frequent Co-Authors

Daniel J. Rader
Daniel J. Rader University of Pennsylvania
Friedhelm Schroeder
Friedhelm Schroeder Texas A&M University
Jerome F. Strauss
Jerome F. Strauss University of Pennsylvania
George H. Rothblat
George H. Rothblat Children's Hospital of Philadelphia
Stephen L. Sturley
Stephen L. Sturley Columbia University Medical Center
Muredach P. Reilly
Muredach P. Reilly Columbia University
Ann B. Kier
Ann B. Kier Texas A&M University
Michael C. Phillips
Michael C. Phillips University of Pennsylvania
Alice H. Lichtenstein
Alice H. Lichtenstein Tufts University
Tony Roscioli
Tony Roscioli University of New South Wales

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