World's Best Scientists 2026 revealed!
Catherine C. Y. Chang

Catherine C. Y. Chang

D-Index & Metrics

Biology and Biochemistry

D-Index
55
Citations
9931
World Ranking
15155
National Ranking
6341

Catherine C. Y. Chang publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Catherine C. Y. Chang sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 129 publications — 16th percentile

16% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Catherine C. Y. Chang D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Catherine C. Y. Chang sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 55 D-Index — 25th percentile

25% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Catherine C. Y. Chang is affiliated with Dartmouth College in the United States and has a research focus spanning medicine, biochemistry, genetics, and molecular biology. Their work prominently intersects with surgery, molecular biology, neurology, physiology, and psychiatry and mental health as subfields of study.

The scientist's investigations largely address topics related to cholesterol and lipid metabolism, peroxisome proliferator-activated receptors, and lipoproteins in cardiovascular health. Other primary research areas include drug transport and resistance mechanisms, lipid membrane structure and behavior, RNA and protein synthesis mechanisms, and receptor mechanisms and signaling.

Chang has contributed to multiple research papers published in a variety of scientific journals. Some representative recent publications include:

  • "Cholesterol, Atherosclerosis, and APOE in Vascular Contributions to Cognitive Impairment and Dementia (VCID): Potential Mechanisms and Therapy," 2021, Frontiers in Aging Neuroscience
  • "Structural insights into the inhibition mechanism of human sterol O-acyltransferase 1 by a competitive inhibitor," 2020, Nature Communications
  • "Acute ACAT1/SOAT1 Blockade Increases MAM Cholesterol and Strengthens ER-Mitochondria Connectivity," 2023, International Journal of Molecular Sciences
  • "Acat1/Soat1 knockout extends the mutant Npc1 mouse lifespan and ameliorates functional deficiencies in multiple organelles of mutant cells," 2022, Proceedings of the National Academy of Sciences
  • "Blocking cholesterol storage to treat Alzheimer's disease," 2021, Exploration of Neuroprotective Therapy

Their frequent co-authors include Ta-Yuan Chang, Thao N. Huynh, Adrianna L. De La Torre, Matthew C. Havrda, and Dylan B. Ness.

Catherine C. Y. Chang's work has been published most often in the International Journal of Molecular Sciences and bioRxiv (Cold Spring Harbor Laboratory), with multiple contributions to each. Other frequently used venues include Frontiers in Aging Neuroscience, Nature Communications, and Proceedings of the National Academy of Sciences.

Best Publications

  • Cholesterol Sensing, Trafficking, and Esterification

    Ta-Yuan Chang;Catherine C Y Chang;Nobutaka Ohgami;Yoshio Yamauchi

  • ACYL-COENZYME A:CHOLESTEROL ACYLTRANSFERASE

    T. Y. Chang;Catherine C. Y. Chang;Dong Cheng

  • Acyl-coenzyme A:cholesterol acyltransferases.

    Ta-Yuan Chang;Bo-Liang Li;Catherine C. Y. Chang;Yasuomi Urano

  • Molecular cloning and functional expression of human acyl-coenzyme A:cholesterol acyltransferase cDNA in mutant Chinese hamster ovary cells.

    Catherine C Y Chang;Ho Young Huh;Kenneth M. Cadigan;Ta Yuan Chang

  • Roles of acyl-coenzyme A:cholesterol acyltransferase-1 and -2.

    Ta-Yuan Chang;Catherine C.Y. Chang;Song Lin;Chunjiang Yu

  • Immunological Quantitation and Localization of ACAT-1 and ACAT-2 in Human Liver and Small Intestine

    Catherine C.Y. Chang;Naomi Sakashita;Kim Ornvold;Oneil Lee

  • Binding between the Niemann–Pick C1 protein and a photoactivatable cholesterol analog requires a functional sterol-sensing domain

    Nobutaka Ohgami;Dennis C. Ko;Matthew Thomas;Matthew P. Scott

  • ACAT1 gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with AD

    Elena Y. Bryleva;Maximillian A. Rogers;Catherine C.Y. Chang;Floyd Buen

  • Activation of Acyl-Coenzyme A:Cholesterol Acyltransferase by Cholesterol or by Oxysterol in a Cell-free System

    Dong Cheng;Catherine C.Y. Chang;Xian-ming Qu;Ta-Yuan Chang

  • Niemann-Pick Type C Disease and Intracellular Cholesterol Trafficking

    Ta-Yuan Chang;Patrick C. Reid;Shigeki Sugii;Nobutaka Ohgami

  • Expression of ACAT-1 Protein in Human Atherosclerotic Lesions and Cultured Human Monocytes-Macrophages

    Akira Miyazaki;Naomi Sakashita;Oneil Lee;Kiyoshi Takahashi

  • Tissue-specific Expression and Cholesterol Regulation of Acylcoenzyme A:Cholesterol Acyltransferase (ACAT) in Mice: MOLECULAR CLONING OF MOUSE ACAT cDNA, CHROMOSOMAL LOCALIZATION, AND REGULATION OF ACAT IN VIVO AND IN VITRO

    Patricia J. Uelmen;Kazuhiro Oka;Merry Sullivan;Catherine C.Y. Chang

  • Molecular Cloning and Characterization of Two Isoforms of Saccharomyces cerevisiae Acyl-CoA:Sterol Acyltransferase

    Chunjiang Yu;Norman J. Kennedy;Catherine C.Y. Chang;Jonathan A. Rothblatt

  • Recombinant acyl-CoA:cholesterol acyltransferase-1 (ACAT-1) purified to essential homogeneity utilizes cholesterol in mixed micelles or in vesicles in a highly cooperative manner.

    Catherine C.Y. Chang;Chi-Yu Gregory Lee;Ellen T. Chang;Jonathan C. Cruz

  • Human acyl-CoA:cholesterol acyltransferase-1 (ACAT-1) gene organization and evidence that the 4.3-kilobase ACAT-1 mRNA is produced from two different chromosomes.

    Bo-Liang Li;Xia-Lu Li;Zhi-Jun Duan;Oneil Lee

  • A novel mouse model of Niemann–Pick type C disease carrying a D1005G-Npc1 mutation comparable to commonly observed human mutations

    Robert A. Maue;Robert W. Burgess;Bing Wang;Christine M. Wooley

  • Acyl-CoA:cholesterol acyltransferases (ACATs/SOATs): Enzymes with multiple sterols as substrates and as activators.

    Maximillian A. Rogers;Jay Liu;Bao-Liang Song;Bo-Liang Li

  • Localization of Human Acyl-Coenzyme A:Cholesterol Acyltransferase-1 (ACAT-1) in Macrophages and in Various Tissues

    Naomi Sakashita;Akira Miyazaki;Motohiro Takeya;Seikoh Horiuchi

  • Investigating the allosterism of acyl-CoA:cholesterol acyltransferase (ACAT) by using various sterols: in vitro and intact cell studies

    Jay Liu;Catherine C. Y. Chang;Emily J. Westover;Douglas F. Covey

  • Immunodepletion experiments suggest that acyl-coenzyme A:cholesterol acyltransferase-1 (ACAT-1) protein plays a major catalytic role in adult human liver, adrenal gland, macrophages, and kidney, but not in intestines.

    Oneil Lee;Catherine C.Y. Chang;William Lee;Ta-Yuan Chang

Frequent Co-Authors

Ta-Yuan Chang
Ta-Yuan Chang Dartmouth College
Bao-Liang Song
Bao-Liang Song Wuhan University
Akira Miyazaki
Akira Miyazaki Showa University
Seikoh Horiuchi
Seikoh Horiuchi Kumamoto University
Li Yang
Li Yang Chinese Academy of Sciences
Motohiro Takeya
Motohiro Takeya Kumamoto Health Science University
William F. Hickey
William F. Hickey Dartmouth College
Kiyoshi Takahashi
Kiyoshi Takahashi Kumamoto University
Shinji Yokoyama
Shinji Yokoyama Chubu University
Salvatore Oddo
Salvatore Oddo Arizona State University

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