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Bao-Liang Song

Bao-Liang Song

D-Index & Metrics

Biology and Biochemistry

D-Index
61
Citations
14694
World Ranking
11274
National Ranking
353

Overview

Bao-Liang Song is affiliated with Wuhan University in China and has a substantial body of research primarily in the fields of Biochemistry, Genetics and Molecular Biology, with significant contributions to Medicine as well. Their work spans multiple subfields including Molecular Biology, Surgery, Cancer Research, Biochemistry, and Cell Biology.

The main topics of research focus on:

  • Cholesterol and Lipid Metabolism
  • Cancer, Lipids, and Metabolism
  • Peroxisome Proliferator-Activated Receptors
  • Epigenetics and DNA Methylation
  • Lipid metabolism and biosynthesis
  • Hedgehog Signaling Pathway Studies
  • Endoplasmic Reticulum Stress and Disease

Several frequent co-authors have collaborated with Bao-Liang Song, including:

  • Jie Luo
  • Ao Hu
  • Xiaolu Zhao
  • Wei Qi
  • Xiongjie Shi

Some notable recent publications are:

  • "Cholesterol metabolism in cancer: mechanisms and therapeutic opportunities," 2020, Nature Metabolism
  • "Sparse deconvolution improves the resolution of live-cell super-resolution fluorescence microscopy," 2021, Nature Biotechnology
  • "High-Performance Electrochemical NO Reduction into NH3 by MoS2 Nanosheet," 2021, Angewandte Chemie International Edition
  • "Feeding induces cholesterol biosynthesis via the mTORC1-USP20-HMGCR axis," 2020, Nature
  • "Exhaustion-associated cholesterol deficiency dampens the cytotoxic arm of antitumor immunity," 2023, Cancer Cell

The most frequent publication venues for the scientist include:

  • Nature Metabolism
  • Science China Life Sciences
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Scientia Sinica Vitae
  • Nature

Best Publications

  • Mechanisms and regulation of cholesterol homeostasis.

    Jie Luo;Hongyuan Yang;Bao-Liang Song

  • Potentiating the antitumour response of CD8 + T cells by modulating cholesterol metabolism

    Wei Yang;Yibing Bai;Ying Xiong;Jin Zhang

  • Cholesterol metabolism in cancer: mechanisms and therapeutic opportunities

    Binlu Huang;Bao-Liang Song;Chenqi Xu

  • The Cholesterol Absorption Inhibitor Ezetimibe Acts by Blocking the Sterol-Induced Internalization of NPC1L1

    Liang Ge;Jing Wang;Wei Qi;Hong-Hua Miao

  • Gp78, a Membrane-Anchored Ubiquitin Ligase, Associates with Insig-1 and Couples Sterol-Regulated Ubiquitination to Degradation of HMG CoA Reductase

    Bao Liang Song;Navdar Sever;Russell A. DeBose-Boyd

  • The metabolic ER stress sensor IRE1α suppresses alternative activation of macrophages and impairs energy expenditure in obesity

    Bo Shan;Xiaoxia Wang;Ying Wu;Chi Xu

  • Insig-dependent Ubiquitination and Degradation of Mammalian 3-Hydroxy-3-methylglutaryl-CoA Reductase Stimulated by Sterols and Geranylgeraniol *

    Navdar Sever;Bao-Liang Song;Daisuke Yabe;Joseph L. Goldstein

  • Cholesterol Transport through Lysosome-Peroxisome Membrane Contacts

    Bei Bei Chu;Bei Bei Chu;Bei Bei Chu;Ya Cheng Liao;Wei Qi;Chang Xie

  • Insig-mediated degradation of HMG CoA reductase stimulated by lanosterol, an intermediate in the synthesis of cholesterol

    Bao Liang Song;Norman B. Javitt;Russell A. DeBose-Boyd

  • Cholesterol Homeostatic Regulator SCAP-SREBP2 Integrates NLRP3 Inflammasome Activation and Cholesterol Biosynthetic Signaling in Macrophages.

    Chuansheng Guo;Zhexu Chi;Danlu Jiang;Ting Xu

  • Insig-dependent Ubiquitination and Degradation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase Stimulated by δ- and γ-Tocotrienols

    Bao Liang Song;Russell A. DeBose-Boyd

  • Cholesterol Modification of Smoothened Is Required for Hedgehog Signaling

    Xu Xiao;Jing-Jie Tang;Chao Peng;Yan Wang

  • Regulation of glucose and lipid metabolism in health and disease

    Ligong Chen;Xiao-Wei Chen;Xun Huang;Bao-Liang Song

  • Sterol-regulated Degradation of Insig-1 Mediated by the Membrane-bound Ubiquitin Ligase gp78

    Joon No Lee;Baoliang Song;Russell A. DeBose-Boyd;Jin Ye

  • SREBP: a novel therapeutic target

    Xu Xiao;Bao-Liang Song

  • Flotillins play an essential role in Niemann-Pick C1-like 1-mediated cholesterol uptake.

    Liang Ge;Wei Qi;Li-Juan Wang;Hong-Hua Miao

  • Feeding induces cholesterol biosynthesis via the mTORC1-USP20-HMGCR axis.

    Xiao-Yi Lu;Xiong-Jie Shi;Ao Hu;Ju-Qiong Wang

  • Acyl-CoA:cholesterol acyltransferases (ACATs/SOATs): Enzymes with multiple sterols as substrates and as activators.

    Maximillian A. Rogers;Jay Liu;Bao-Liang Song;Bo-Liang Li

  • Discovery of a potent HMG-CoA reductase degrader that eliminates statin-induced reductase accumulation and lowers cholesterol.

    Shi-You Jiang;Hui Li;Jing-Jie Tang;Jie Wang

  • The biogenesis of lipid droplets: Lipids take center stage.

    Mingming Gao;Xun Huang;Bao-Liang Song;Hongyuan Yang

Frequent Co-Authors

Ta-Yuan Chang
Ta-Yuan Chang Dartmouth College
Catherine C. Y. Chang
Catherine C. Y. Chang Dartmouth College
Hongyuan Yang
Hongyuan Yang University of New South Wales
Housheng Hansen He
Housheng Hansen He University of Toronto
Zhengtao Wang
Zhengtao Wang Shanghai University
Huiyong Yin
Huiyong Yin Chinese Academy of Sciences
Charles Antzelevitch
Charles Antzelevitch Lankenau Institute for Medical Research
Li Yang
Li Yang Chinese Academy of Sciences
Bin Zhou
Bin Zhou Chinese Academy of Sciences
Guang Ning
Guang Ning Shanghai Jiao Tong University

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