His main research concerns Lipid droplet, Biochemistry, Cell biology, Saccharomyces cerevisiae and Seipin. His biological study spans a wide range of topics, including Mutant and Organelle. His Organelle research incorporates elements of Biogenesis and Phosphatidylcholine.
His Cell biology study incorporates themes from Lipid metabolism and Cholesterol, Sterol. His Seipin research incorporates a variety of disciplines, including BSCL2 and Phosphatidic acid. His Endoplasmic reticulum research is multidisciplinary, relying on both Membrane contact site and Protein degradation.
Hongyuan Yang mainly investigates Cell biology, Biochemistry, Lipid droplet, Seipin and Endocrinology. His work in Saccharomyces cerevisiae, Mutant, Yeast, Schizosaccharomyces pombe and Mitochondrion are all subfields of Biochemistry research. His studies deal with areas such as Sterol esterification and Biosynthesis as well as Saccharomyces cerevisiae.
The concepts of his Lipid droplet study are interwoven with issues in Adipocyte, Biogenesis, Phosphatidic acid, Lipid metabolism and Organelle. Seipin is intertwined with BSCL2 and Adipogenesis in his study. Genetics is closely connected to Internal medicine in his research, which is encompassed under the umbrella topic of Endocrinology.
Hongyuan Yang mostly deals with Cell biology, Lipid droplet, Endoplasmic reticulum, Internal medicine and Endocrinology. His Cell biology research integrates issues from Cell and Cholesterol, Sterol. In his articles, he combines various disciplines, including Lipid droplet and Seipin.
In his research on the topic of Endoplasmic reticulum, Phosphatidylserine is strongly related with Integral membrane protein. His work on LDL receptor, Insulin resistance, Steatosis and Adipose tissue as part of general Internal medicine study is frequently linked to Fat removal, bridging the gap between disciplines. His research in Organelle intersects with topics in Phosphatidylinositol and Yeast.
His primary scientific interests are in Cell biology, Lipid droplet, Endoplasmic reticulum, Cholesterol and Organelle. Particularly relevant to Intracellular is his body of work in Cell biology. The various areas that he examines in his Lipid droplet study include Secretion and Function.
He integrates Endoplasmic reticulum and Seipin in his studies. His Cholesterol study combines topics in areas such as Pi and Biosynthesis. To a larger extent, he studies Biochemistry with the aim of understanding Lipid Transport.
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Fld1p, a functional homologue of human seipin, regulates the size of lipid droplets in yeast.
Weihua Fei;Guanghou Shui;Bruno Gaeta;Ximing Du.
Journal of Cell Biology (2008)
Sterol Esterification in Yeast: A Two-Gene Process
Hongyuan Yang;Martin Bard;Debora A. Bruner;Anne Gleeson.
A role for phosphatidic acid in the formation of "supersized" lipid droplets.
Weihua Fei;Guanghou Shui;Yuxi Zhang;Natalie Krahmer.
PLOS Genetics (2011)
Fsp27 promotes lipid droplet growth by lipid exchange and transfer at lipid droplet contact sites
Jingyi Gong;Zhiqi Sun;Lizhen Wu;Wenyi Xu.
Journal of Cell Biology (2011)
A role for oxysterol-binding protein–related protein 5 in endosomal cholesterol trafficking
Ximing Du;Jaspal Kumar;Charles Ferguson;Timothy A. Schulz.
Journal of Cell Biology (2011)
Up-Regulation of Mitochondrial Activity and Acquirement of Brown Adipose Tissue-Like Property in the White Adipose Tissue of Fsp27 Deficient Mice
Shen Yon Toh;Shen Yon Toh;Shen Yon Toh;Jingyi Gong;Guoli Du;John Zhong Li;John Zhong Li.
PLOS ONE (2008)
Cholesterol Transport through Lysosome-Peroxisome Membrane Contacts
Bei Bei Chu;Bei Bei Chu;Bei Bei Chu;Ya Cheng Liao;Wei Qi;Chang Xie.
Perilipin1 promotes unilocular lipid droplet formation through the activation of Fsp27 in adipocytes
Zhiqi Sun;Jingyi Gong;Han Wu;Wenyi Xu.
Nature Communications (2013)
Antitumor Activity and Underlying Mechanisms of Ganopoly, The Refined Polysaccharides Extracted from Ganoderma Lucidum, in Mice
Yihuai Gao;He Gao;Eli Chan;Wenbo Tang.
Immunological Investigations (2005)
Controlling the size of lipid droplets: lipid and protein factors.
Hongyuan Yang;Anne Galea;Vladimir Sytnyk;Merlin Crossley.
Current Opinion in Cell Biology (2012)
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