World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
64
Citations
14277
World Ranking
9696
National Ranking
257

Overview

Hongyuan Yang is affiliated with the University of New South Wales in Australia and has contributed extensively to research in biochemistry, genetics, molecular biology, and medicine. Their scholarly work spans 83 publications in biochemistry, genetics, and molecular biology and 66 in medicine. Yang's research focuses on several subfields including molecular biology, biochemistry, surgery, physiology, and oncology.

The scientist's primary topics of study include lipid metabolism and biosynthesis, cholesterol and lipid metabolism, adipose tissue and metabolism, endoplasmic reticulum stress and disease, CAR-T cell therapy research, peroxisome proliferator-activated receptors, and nuclear structure and function.

Recent publications by Hongyuan Yang include these works:

  • Lipid droplet biogenesis and functions in health and disease (2023, Nature Reviews Endocrinology)
  • Structural Basis of Low-pH-Dependent Lysosomal Cholesterol Egress by NPC1 and NPC2 (2020, Cell)
  • TMEM41B and VMP1 are scramblases and regulate the distribution of cholesterol and phosphatidylserine (2021, The Journal of Cell Biology)
  • TMAVA, a Metabolite of Intestinal Microbes, Is Increased in Plasma From Patients With Liver Steatosis, Inhibits γ-Butyrobetaine Hydroxylase, and Exacerbates Fatty Liver in Mice (2020, Gastroenterology)
  • Seipin accumulates and traps diacylglycerols and triglycerides in its ring-like structure (2021, Proceedings of the National Academy of Sciences)

Frequent co-authors in Hongyuan Yang's publications include Ximing Du, Mingming Gao, Andrew J. Brown, Ivan Lukmantara, and Mingshan Cheng. Collaborations with these researchers have contributed to the production of multiple peer-reviewed articles.

Hongyuan Yang's work has been published frequently in venues such as The Journal of Cell Biology, bioRxiv (Cold Spring Harbor Laboratory), Proceedings of the National Academy of Sciences, The FASEB Journal, and Frontiers in Veterinary Science.

Best Publications

  • Mechanisms and regulation of cholesterol homeostasis.

    Jie Luo;Hongyuan Yang;Bao-Liang Song

  • Fld1p, a functional homologue of human seipin, regulates the size of lipid droplets in yeast.

    Weihua Fei;Guanghou Shui;Bruno Gaeta;Ximing Du

  • Cholesterol Transport through Lysosome-Peroxisome Membrane Contacts

    Bei Bei Chu;Bei Bei Chu;Bei Bei Chu;Ya Cheng Liao;Wei Qi;Chang Xie

  • Fsp27 promotes lipid droplet growth by lipid exchange and transfer at lipid droplet contact sites

    Jingyi Gong;Zhiqi Sun;Lizhen Wu;Wenyi Xu

  • A role for phosphatidic acid in the formation of "supersized" lipid droplets.

    Weihua Fei;Guanghou Shui;Yuxi Zhang;Natalie Krahmer

  • Sterol Esterification in Yeast: A Two-Gene Process

    Hongyuan Yang;Martin Bard;Debora A. Bruner;Anne Gleeson

  • A role for oxysterol-binding protein–related protein 5 in endosomal cholesterol trafficking

    Ximing Du;Jaspal Kumar;Charles Ferguson;Timothy A. Schulz

  • Up-Regulation of Mitochondrial Activity and Acquirement of Brown Adipose Tissue-Like Property in the White Adipose Tissue of Fsp27 Deficient Mice

    Shen Yon Toh;Shen Yon Toh;Shen Yon Toh;Jingyi Gong;Guoli Du;John Zhong Li;John Zhong Li

  • Perilipin1 promotes unilocular lipid droplet formation through the activation of Fsp27 in adipocytes

    Zhiqi Sun;Jingyi Gong;Han Wu;Wenyi Xu

  • Controlling the size of lipid droplets: lipid and protein factors.

    Hongyuan Yang;Anne Galea;Vladimir Sytnyk;Merlin Crossley

  • Rab18 promotes lipid droplet (LD) growth by tethering the ER to LDs through SNARE and NRZ interactions.

    Dijin Xu;Yuqi Li;Lizhen Wu;Ying Li

  • Conditions of endoplasmic reticulum stress stimulate lipid droplet formation in Saccharomyces cerevisiae

    Weihua Fei;Han Wang;Xin Fu;Christopher Bielby

  • Seipin ablation in mice results in severe generalized lipodystrophy

    Xin Cui;Yuhui Wang;Yin Tang;Yixiao Liu

  • Human SEIPIN Binds Anionic Phospholipids.

    Renhong Yan;Hongwu Qian;Ivan Lukmantara;Mingming Gao

  • Antitumor Activity and Underlying Mechanisms of Ganopoly, The Refined Polysaccharides Extracted from Ganoderma Lucidum, in Mice

    Yihuai Gao;He Gao;Eli Chan;Wenbo Tang

  • Monitoring of immune responses to a herbal immuno-modulator in patients with advanced colorectal cancer.

    Xiao Chen;Ze Ping Hu;Xiao Xia Yang;Min Huang

  • ORP5 and ORP8 bind phosphatidylinositol-4, 5-biphosphate (PtdIns(4,5)P 2) and regulate its level at the plasma membrane.

    Rajesh Ghai;Rajesh Ghai;Ximing Du;Huan Wang;Jiangqing Dong

  • Toward one step analysis of cellular lipidomes using liquid chromatography coupled with mass spectrometry: application to Saccharomyces cerevisiae and Schizosaccharomyces pombe lipidomics

    Guanghou Shui;Xue Li Guan;Choon Pei Low;Gek Huey Chua

  • SEIPIN Regulates Lipid Droplet Expansion and Adipocyte Development by Modulating the Activity of Glycerol-3-phosphate Acyltransferase.

    Martin Pagac;Daniel E. Cooper;Yanfei Qi;Ivan E. Lukmantara

  • Tissue-autonomous function of Drosophila seipin in preventing ectopic lipid droplet formation.

    Yuan Tian;Junfeng Bi;Guanghou Shui;Zhonghua Liu

Frequent Co-Authors

Andrew J. Brown
Andrew J. Brown University of New South Wales
Guanghou Shui
Guanghou Shui Chinese Academy of Sciences
Robert G. Parton
Robert G. Parton University of Queensland
Markus R. Wenk
Markus R. Wenk Hamad bin Khalifa University
Ian W. Dawes
Ian W. Dawes University of New South Wales
Shu-Feng Zhou
Shu-Feng Zhou Huaqiao University
Stephen L. Sturley
Stephen L. Sturley Columbia University Medical Center
Charles Ferguson
Charles Ferguson University of Queensland
Bao-Liang Song
Bao-Liang Song Wuhan University
Nieng Yan
Nieng Yan Princeton University

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