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Biology and Biochemistry

D-Index
61
Citations
18063
World Ranking
11165
National Ranking
4833

Overview

William A. Prinz is affiliated with The University of Texas Southwestern Medical Center in the United States. Their research primarily falls within the field of Biochemistry, Genetics and Molecular Biology, with notable contributions in Molecular Biology, Biochemistry, Cell Biology, Plant Science, and Physiology.

The scientist's main research topics include lipid metabolism and biosynthesis, photosynthetic processes and mechanisms, microbial metabolic engineering and bioproduction, endoplasmic reticulum stress and disease, cellular transport and secretion, lipid membrane structure and behavior, and peroxisome proliferator-activated receptors.

William A. Prinz has contributed numerous publications, frequently appearing in several prominent scholarly venues. These include:

  • The Journal of Cell Biology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Biological Chemistry
  • Cell
  • Science

Their recent published papers reflect an ongoing focus on cellular and molecular mechanisms related to lipid biology and organelle function. Key papers include:

  • "Mechanisms of nonvesicular lipid transport" (2021) in The Journal of Cell Biology
  • "Making the connection: How membrane contact sites have changed our view of organelle biology" (2024) in Cell
  • "Seipin and Nem1 establish discrete ER subdomains to initiate yeast lipid droplet biogenesis" (2020) in The Journal of Cell Biology
  • "Vps13-like proteins provide phosphatidylethanolamine for GPI anchor synthesis in the ER" (2022) in The Journal of Cell Biology
  • "VPS13D promotes peroxisome biogenesis" (2021) in The Journal of Cell Biology

The scientist often collaborates with several frequent co-authors, including Alexandre Toulmay, Subhrajit Banerjee, Vineet Choudhary, Roger Schneiter, and Xiaofei Bai. These collaborations highlight an interdisciplinary approach to research in molecular and cellular biology.

Best Publications

  • A Class of Membrane Proteins Shaping the Tubular Endoplasmic Reticulum

    Gia K. Voeltz;William A. Prinz;Yoko Shibata;Julia M. Rist

  • The Role of the Thioredoxin and Glutaredoxin Pathways in Reducing Protein Disulfide Bonds in the Escherichia coliCytoplasm

    William A. Prinz;Fredrik Åslund;Arne Holmgren;Jon Beckwith

  • Membrane expansion alleviates endoplasmic reticulum stress independently of the unfolded protein response

    Sebastian Schuck;William A. Prinz;Kurt S. Thorn;Christiane Voss

  • A class of dynamin-like GTPases involved in the generation of the tubular ER network.

    Junjie Hu;Yoko Shibata;Peng-Peng Zhu;Christiane Voss

  • The functional universe of membrane contact sites.

    William A Prinz;Alexandre Toulmay;Tamas Balla

  • Mechanisms Determining the Morphology of the Peripheral ER

    Yoko Shibata;Yoko Shibata;Tom Shemesh;William A. Prinz;Alexander F. Palazzo;Alexander F. Palazzo

  • Bridging the gap: Membrane contact sites in signaling, metabolism, and organelle dynamics

    William A. Prinz

  • Membrane proteins of the endoplasmic reticulum induce high-curvature tubules.

    Junjie Hu;Yoko Shibata;Christiane Voss;Tom Shemesh

  • Form Follows Function: The Importance of Endoplasmic Reticulum Shape

    L M Westrate;J E Lee;W A Prinz;G K Voeltz

  • Structural mechanism for sterol sensing and transport by OSBP-related proteins

    Young Jun Im;Sumana Raychaudhuri;William A. Prinz;James H. Hurley

  • The reticulon and DP1/Yop1p proteins form immobile oligomers in the tubular endoplasmic reticulum.

    Yoko Shibata;Christiane Voss;Julia M. Rist;Junjie Hu

  • Mutants affecting the structure of the cortical endoplasmic reticulum in Saccharomyces cerevisiae

    William A. Prinz;Lara Grzyb;Marten Veenhuis;Jason A. Kahana

  • Nonvesicular sterol movement from plasma membrane to ER requires oxysterol-binding protein–related proteins and phosphoinositides

    Sumana Raychaudhuri;Young Jun Im;James H. Hurley;William A. Prinz

  • Ltc1 is an ER-localized sterol transporter and a component of ER–mitochondria and ER–vacuole contacts

    Andrew Murley;Reta D. Sarsam;Alexandre Toulmay;Justin Yamada

  • A role for oxysterol-binding protein–related protein 5 in endosomal cholesterol trafficking

    Ximing Du;Jaspal Kumar;Charles Ferguson;Timothy A. Schulz

  • A conserved endoplasmic reticulum membrane protein complex (EMC) facilitates phospholipid transfer from the ER to mitochondria.

    Sujoy Lahiri;Jesse T. Chao;Shabnam Tavassoli;Andrew K. O. Wong

  • Phosphatidic Acid Is a pH Biosensor That Links Membrane Biogenesis to Metabolism

    Barry P. Young;John J. H. Shin;Rick Orij;Jesse T. Chao

  • A conserved membrane-binding domain targets proteins to organelle contact sites.

    Alexandre Toulmay;William A. Prinz

  • A Conserved Family of Proteins Facilitates Nascent Lipid Droplet Budding from the ER

    Vineet Choudhary;Namrata Ojha;Andy Golden;William A. Prinz

  • Direct imaging reveals stable, micrometer-scale lipid domains that segregate proteins in live cells

    Alexandre Toulmay;William A. Prinz

Frequent Co-Authors

Tom A. Rapoport
Tom A. Rapoport Harvard University
Timothy P. Levine
Timothy P. Levine University College London
Jodi Nunnari
Jodi Nunnari University of California, Davis
John A. Hanover
John A. Hanover National Institutes of Health
Roger Schneiter
Roger Schneiter University of Fribourg
Rodolfo Ghirlando
Rodolfo Ghirlando National Institutes of Health
Markus R. Wenk
Markus R. Wenk Hamad bin Khalifa University
Craig Blackstone
Craig Blackstone Massachusetts General Hospital
Caroline C. Philpott
Caroline C. Philpott National Institutes of Health
Susan A. Henry
Susan A. Henry Cornell University

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