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Medicine

D-Index
90
Citations
22665
World Ranking
12386
National Ranking
6342

Overview

William E. Sonntag is affiliated with the University of Oklahoma Health Sciences Center in the United States. Their research work primarily spans the fields of Medicine and Neuroscience, with a strong emphasis on Neurology, Physiology, Cognitive Neuroscience, Molecular Biology, and Radiology, Nuclear Medicine and Imaging.

Key topics addressed in their research include:

  • Neuroinflammation and Neurodegeneration Mechanisms
  • Growth Hormone and Insulin-like Growth Factors
  • Functional Brain Connectivity Studies
  • Telomeres, Telomerase, and Senescence
  • Mitochondrial Function and Pathology
  • Heart Rate Variability and Autonomic Control
  • Optical Imaging and Spectroscopy Techniques

Their publication record shows a focus on journals such as:

  • GeroScience (8 publications)
  • Frontiers in Aging Neuroscience (2 publications)
  • Frontiers in Behavioral Neuroscience (1 publication)
  • Scientific Reports (1 publication)
  • Advanced Science (1 publication)

Recent papers authored by William E. Sonntag include:

  • "Pharmacological or genetic depletion of senescent astrocytes prevents whole brain irradiation-induced impairment of neurovascular coupling responses protecting cognitive function in mice" (2020, GeroScience)
  • "Measuring Behavior in the Home Cage: Study Design, Applications, Challenges, and Perspectives" (2021, Frontiers in Behavioral Neuroscience)
  • "Sleep deprivation impairs cognitive performance, alters task-associated cerebral blood flow and decreases cortical neurovascular coupling-related hemodynamic responses" (2021, Scientific Reports)
  • "Endothelial deficiency of insulin-like growth factor-1 receptor (IGF1R) impairs neurovascular coupling responses in mice, mimicking aspects of the brain aging phenotype" (2021, GeroScience)
  • "Elimination of senescent cells by treatment with Navitoclax/ABT263 reverses whole brain irradiation-induced blood-brain barrier disruption in the mouse brain" (2023, GeroScience)

The scientist frequently collaborates with a group of co-authors including:

  • Andriy Yabluchanskiy
  • Anna Csiszár
  • Zoltán Ungvári
  • Stefano Tarantini
  • Ádám Nyúl-Tóth

Best Publications

  • Mechanisms of vascular aging: new perspectives.

    Zoltan Ungvari;Gabor Kaley;Rafael de Cabo;William E. Sonntag

  • Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2.

    Zoltan I Ungvari;Zsolt Bagi;Attila Feher;Fabio A. Recchia

  • Intracerebroventricular infusion of insulin-like growth factor-I ameliorates the age-related decline in hippocampal neurogenesis

    R.J Lichtenwalner;M.E Forbes;S.A Bennett;C.D Lynch

  • Obesity in Aging Exacerbates Blood–Brain Barrier Disruption, Neuroinflammation, and Oxidative Stress in the Mouse Hippocampus: Effects on Expression of Genes Involved in Beta-Amyloid Generation and Alzheimer’s Disease

    Zsuzsanna Tucsek;Peter Toth;Danuta Sosnowska;Tripti Gautam

  • Decreases in cerebral microvasculature with age are associated with the decline in growth hormone and insulin-like growth factor 1.

    William E. Sonntag;Colleen D. Lynch;Paula T. Cooney;Phillip M. Hutchins

  • Decreased pulsatile release of growth hormone in old male rats.

    William E. Sonntag;Richard W. Steger;Lloyd J. Forman;Joseph Meites

  • Insulin-like growth factor-1 ameliorates age-related behavioral deficits

    A.L Markowska;M Mooney;W.E Sonntag

  • Growth hormone and insulin-like growth factor-1 (IGF-1) and their influence on cognitive aging.

    William E. Sonntag;Melinda Ramsey;Christy S. Carter

  • Microvascular plasticity in aging

    David R. Riddle;William E. Sonntag;Robin J. Lichtenwalner

  • Vascular oxidative stress in aging: a homeostatic failure due to dysregulation of Nrf2-mediated antioxidant response

    Zoltan I Ungvari;Lora Bailey-Downs;Danuta Sosnowska;Tripti Gautam

  • Influence of age and long-term dietary restriction on plasma insulin-like growth factor-1 (IGF-1), IGF-1 gene expression, and IGF-1 binding proteins

    Charles R. Breese;Rhonda L. Ingram;William E. Sonntag

  • Pleiotropic Effects of Growth Hormone and Insulin-like Growth Factor (IGF)-1 on Biological Aging: Inferences From Moderate Caloric-Restricted Animals

    William E. Sonntag;Colleen D. Lynch;William T. Cefalu;Rhonda L. Ingram

  • Biomarkers of aging: From primitive organisms to humans

    Robert N. Butler;Richard Sprott;Huber Warner;Jeffrey Bland

  • Age-Associated Vascular Oxidative Stress, Nrf2 Dysfunction, and NF-κB Activation in the Nonhuman Primate Macaca mulatta

    Zoltan Ungvari;Lora Bailey-Downs;Tripti Gautam;Danuta Sosnowska

  • Age-related autoregulatory dysfunction and cerebromicrovascular injury in mice with angiotensin II-induced hypertension

    Peter Toth;Zsuzsanna Tucsek;Danuta Sosnowska;Tripti Gautam

  • Caloric restriction and age affect synaptic proteins in hippocampal CA3 and spatial learning ability.

    Michelle M. Adams;Lei Shi;M. Constance Linville;M. Elizabeth Forbes

  • Growth hormone, insulin-like growth factor-1 and the aging cardiovascular system.

    Amir S Khan;David C Sane;Thomas Wannenburg;William E Sonntag

  • Reduction in the chondrocyte response to insulin‐like growth factor 1 in aging and osteoarthritis: Studies in a non‐human primate model of naturally occurring disease

    Richard F. Loeser;Gouri Shanker;Cathy S. Carlson;Jean F. Gardin

  • The effects of growth hormone and IGF‐1 deficiency on cerebrovascular and brain ageing

    William E. Sonntag;Colleen Lynch;Phillip Thornton;Amir Khan

  • Spatial Learning and Memory Deficits after Whole-Brain Irradiation are Associated with Changes in NMDA Receptor Subunits in the Hippocampus

    Lei Shi;Michelle M. Adams;Ashley Long;Christy C. Carter

Frequent Co-Authors

Zoltan Ungvari
Zoltan Ungvari University of Oklahoma Health Sciences Center
Anna Csiszar
Anna Csiszar University of Oklahoma Health Sciences Center
Akos Koller
Akos Koller New York Medical College
Joseph Meites
Joseph Meites Michigan State University
Jonathan D. Wren
Jonathan D. Wren Oklahoma Medical Research Foundation
Judy K. Brunso-Bechtold
Judy K. Brunso-Bechtold Wake Forest University
Xiaowei Xu
Xiaowei Xu University of Pennsylvania
Rafael de Cabo
Rafael de Cabo National Institutes of Health
Arlan Richardson
Arlan Richardson University of Oklahoma Health Sciences Center
Michal L. Schwartzman
Michal L. Schwartzman New York Medical College

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