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Medicine

D-Index
127
Citations
70516
World Ranking
2800
National Ranking
1562

Overview

Michael R. Zile is affiliated with the Medical University of South Carolina in the United States. Their research primarily focuses on medicine, with a significant emphasis on cardiology and cardiovascular medicine. Their work also spans surgery, pulmonary and respiratory medicine, endocrinology, diabetes and metabolism, and epidemiology.

The scientist has published extensively on topics related to heart failure treatment and management, cardiovascular function and risk factors, cardiac pacing and defibrillation studies, diabetes treatment and management, blood pressure and hypertension studies, cardiac fibrosis and remodeling, as well as heart rate variability and autonomic control.

Frequent co-authors in their research include:

  • John J.V. McMurray
  • Scott D. Solomon
  • Akshay S. Desai
  • Milton Packer
  • Pardeep S. Jhund

They have a consistent presence in several publication venues. These include:

  • Journal of the American College of Cardiology
  • European Journal of Heart Failure
  • European Heart Journal
  • Circulation
  • JACC Heart Failure

Some of their recent papers include:

  • "Tirzepatide for Heart Failure with Preserved Ejection Fraction and Obesity," 2024, New England Journal of Medicine
  • "Haemodynamic-guided management of heart failure (GUIDE-HF): a randomised controlled trial," 2021, The Lancet
  • "From Systemic Inflammation to Myocardial Fibrosis," 2021, Circulation Research
  • "Anthropometric measures and adverse outcomes in heart failure with reduced ejection fraction: revisiting the obesity paradox," 2023, European Heart Journal
  • "Comparison of BNP and NT-proBNP in Patients With Heart Failure and Reduced Ejection Fraction," 2020, Circulation Heart Failure

Best Publications

  • Angiotensin-neprilysin inhibition versus enalapril in heart failure.

    John J. V. McMurray;Milton Packer;Akshay S. Desai;Jianjian Gong

  • Irbesartan in patients with heart failure and preserved ejection fraction

    Barry M. Massie;Peter E. Carson;John J. McMurray;Michel Komajda

  • Diastolic Heart Failure — Abnormalities in Active Relaxation and Passive Stiffness of the Left Ventricle

    Michael R. Zile;Catalin F. Baicu;William H. Gaasch

  • Angiotensin-Neprilysin inhibition in heart failure with preserved ejection fraction

    Scott D. Solomon;John J.V. McMurray;Inder S. Anand;Junbo Ge

  • New Concepts in Diastolic Dysfunction and Diastolic Heart Failure: Part I Diagnosis, Prognosis, and Measurements of Diastolic Function

    Michael R. Zile;Dirk L. Brutsaert

  • New concepts in diastolic dysfunction and diastolic heart failure: Part II: causal mechanisms and treatment.

    Michael R. Zile;Dirk L. Brutsaert

  • The angiotensin receptor neprilysin inhibitor LCZ696 in heart failure with preserved ejection fraction: A phase 2 double-blind randomised controlled trial

    Scott D. Solomon;Michael R. Zile;Burkert Pieske;Adriaan A Voors

  • Phenotype-Specific Treatment of Heart Failure With Preserved Ejection Fraction A Multiorgan Roadmap

    Sanjiv J. Shah;Dalane W. Kitzman;Barry A. Borlaug;Loek van Heerebeek

  • Impaired Systolic Function by Strain Imaging in Heart Failure With Preserved Ejection Fraction

    Elisabeth Kraigher-Krainer;Amil M. Shah;Deepak K. Gupta;Angela Santos

  • Effects of Digoxin on Morbidity and Mortality in Diastolic Heart Failure The Ancillary Digitalis Investigation Group Trial

    Ali Ahmed;Michael W. Rich;Jerome L. Fleg;Michael R. Zile

  • Heart failure with a normal ejection fraction: Is measurement of diastolic function necessary to make the diagnosis of diastolic heart failure?

    Michael R. Zile;William H. Gaasch;John D. Carroll;Marc D. Feldman

  • Angiotensin Receptor Neprilysin Inhibition Compared With Enalapril on the Risk of Clinical Progression in Surviving Patients With Heart Failure

    Milton Packer;John J. V. McMurray;Akshay S. Desai;Jianjian Gong

  • Transition from chronic compensated to acute decompensated heart failure: pathophysiological insights obtained from continuous monitoring of intracardiac pressures.

    Michael R. Zile;Tom D. Bennett;Martin St. John Sutton;Yong K. Cho

  • Myocardial stiffness in patients with heart failure and a preserved ejection fraction contributions of collagen and titin

    Michael R. Zile;Catalin F. Baicu;John S. Ikonomidis;Robert E. Stroud

  • Prevalence and Significance of Alterations in Cardiac Structure and Function in Patients With Heart Failure and a Preserved Ejection Fraction

    Michael R. Zile;John S. Gottdiener;Scott J. Hetzel;John J. McMurray

  • Randomized Controlled Trial of an Implantable Continuous Hemodynamic Monitor in Patients With Advanced Heart Failure: The COMPASS-HF Study

    Robert C. Bourge;William T. Abraham;Philip B. Adamson;Mark F. Aaron

  • Matrix Metalloproteinases/Tissue Inhibitors of Metalloproteinases: Relationship Between Changes in Proteolytic Determinants of Matrix Composition and Structural, Functional, and Clinical Manifestations of Hypertensive Heart Disease

    S. Hinan Ahmed;Leslie L. Clark;Weems R. Pennington;Carson S. Webb

  • Role of Biomarkers for the Prevention, Assessment, and Management of Heart Failure: A Scientific Statement From the American Heart Association

    Sheryl L. Chow;Alan S. Maisel;Inder Anand;Biykem Bozkurt

  • Dual angiotensin receptor and neprilysin inhibition as an alternative to angiotensin- converting enzyme inhibition in patients with chronic systolic heart failure: rationale for and design of the Prospective comparison of ARNI with ACEI to Determine Impact on Global Mortality and morbidity in Heart Failure trial (PARADIGM-HF)

    John J. V. McMurray;Milton Packer;Akshay S. Desai;Jim Gong

  • Heart failure/transplant: abstractDiastolic heart failure-abnormalities in active relaxation and passive stiffness of the left ventricle

    M.R Zile;C.F Baicu;W.H Gaasch

Frequent Co-Authors

John J.V. McMurray
John J.V. McMurray University of Glasgow
Scott D. Solomon
Scott D. Solomon Brigham and Women's Hospital
Karl Swedberg
Karl Swedberg University of Gothenburg
Milton Packer
Milton Packer Baylor University Medical Center
Francis G. Spinale
Francis G. Spinale University of South Carolina
Akshay S. Desai
Akshay S. Desai Brigham and Women's Hospital
Brian Claggett
Brian Claggett Brigham and Women's Hospital
Pardeep S. Jhund
Pardeep S. Jhund University of Glasgow
Inder S. Anand
Inder S. Anand University of Minnesota
Robert S. McKelvie
Robert S. McKelvie University of Western Ontario

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