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D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
11739
World Ranking
14396
National Ranking
6061

Overview

Lawrence Salkoff is affiliated with Washington University in St. Louis in the United States. Their research principally spans the fields of Biochemistry, Genetics and Molecular Biology, Medicine, and Neuroscience, with a strong focus on Molecular Biology and Cellular and Molecular Neuroscience. The scientist's work also extends into Cardiology and Cardiovascular Medicine, Psychiatry and Mental Health, and Organic Chemistry.

The main topics covered in their body of research include:

  • Ion channel regulation and function
  • Cardiac electrophysiology and arrhythmias
  • Neuroscience and Neural Engineering
  • Genetic Neurodegenerative Diseases
  • Epilepsy research and treatment
  • Coordination Chemistry and Organometallics
  • Photoreceptor and optogenetics research

Salkoff has contributed to several publication venues, with recurrent publications appearing in:

  • The Journal of General Physiology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • Frontiers in Pharmacology
  • Biophysical Journal

Recent papers authored include:

  • "Coupling of Ca 2+ and voltage activation in BK channels through the αB helix/voltage sensor interface," 2020, Proceedings of the National Academy of Sciences
  • "BK channels of five different subunit combinations underlie the de novo KCNMA1 G375R channelopathy," 2023, The Journal of General Physiology
  • "BK channels of five different subunit combinations underlie the de novo KCNMA1 G375R channelopathy," 2021, bioRxiv (Cold Spring Harbor Laboratory)
  • "Coupling of Ca2+and voltage activation in BK channels through the αB helix/voltage sensor interface," 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • "Case Report: Targeted treatment by fluoxetine/norfluoxetine of a KCNC2 variant causing developmental and epileptic encephalopathy," 2025, Frontiers in Pharmacology

Frequent collaborators in Salkoff's research include Karl L. Magleby, Yanyan Geng, Alice Butler, Zengqin Deng, and Guohui Zhang. Among these, Karl L. Magleby has the highest number of coauthorships.

Best Publications

  • mSlo, a Complex Mouse Gene Encoding "Maxi" Calcium-Activated Potassium Channels

    Alice Butler;Susan Tsunoda;David P. McCobb;Aguan Wei

  • High-conductance potassium channels of the SLO family

    Lawrence Salkoff;Alice Butler;Gonzalo Ferreira;Celia Santi

  • A novel calcium-sensing domain in the BK channel.

    Matthew Schreiber;Lawrence Salkoff

  • K+ current diversity is produced by an extended gene family conserved in Drosophila and mouse.

    Aguan Wei;Manuel Covarrubias;Alice Butler;Keith Baker

  • An essential 'set' of K+ channels conserved in flies, mice and humans.

    Lawrence Salkoff;Keith Baker;Alice Butler;Manuel Covarrubias

  • Shaker, Shal, Shab, and Shaw express independent K^+ current systems

    Manuel Covarrubias;Aguan Wei;Lawrence Salkoff

  • A family of putative potassium channel genes in Drosophila.

    Alice Butler;Aguan Wei;Keith Baker;Lawrence Salkoff

  • Calcium sensitivity of BK-type KCa channels determined by a separable domain.

    Aguan Wei;Christopher Solaro;Christopher Lingle;Lawrence Salkoff

  • Eight potassium channel families revealed by the C. elegans genome project

    A Wei;T Jegla;L Salkoff

  • Genomic organization and deduced amino acid sequence of a putative sodium channel gene in Drosophila.

    Lawrence Salkoff;Alice Butler;Aguan Wei;Nancy Scavarda

  • Slo3, a Novel pH-sensitive K+ Channel from Mammalian Spermatocytes

    Matthew Schreiber;Aguan Wei;Alex Yuan;Joseph Gaut

  • The Sodium-Activated Potassium Channel Is Encoded by a Member of the Slo Gene Family

    Alex Yuan;Celia M. Santi;Aguan Wei;Zhao Wen Wang

  • SLO-1 Potassium Channels Control Quantal Content of Neurotransmitter Release at the C. elegans Neuromuscular Junction

    Zhao Wen Wang;Owais Saifee;Michael L. Nonet;Lawrence Salkoff

  • Genetic modification of potassium channels in Drosophila Shaker mutants.

    Lawrence Salkoff;Robert Wyman

  • The SLO3 sperm-specific potassium channel plays a vital role in male fertility

    Celia M. Santi;Pablo Martínez-López;José Luis de la Vega-Beltrán;Alice Butler

  • mShal, a subfamily of A-type K+ channel cloned from mammalian brain.

    Michael D. Pak;Keith Baker;Manuel Covarrubias;Alice Butler

  • A human calcium-activated potassium channel gene expressed in vascular smooth muscle

    David P. McCOBB;Natalie L. Fowler;Terence Featherstone;Christopher J. Lingle

  • Intracorporal injection of hSlo cDNA in rats produces physiologically relevant alterations in penile function

    G. J. Christ;J. Rehman;N. Day;L. Salkoff

  • Transplantable sites confer calcium sensitivity to BK channels.

    Matthew Schreiber;Alex Yuan;Lawrence Salkoff

  • TRPγ, a Drosophila TRP–Related Subunit, Forms a Regulated Cation Channel with TRPL

    X.-Z.Shawn Xu;Fred Chien;Alice Butler;Larry Salkoff

Frequent Co-Authors

Karl L. Magleby
Karl L. Magleby University of Miami
Michael L. Nonet
Michael L. Nonet Washington University in St. Louis
Alberto Darszon
Alberto Darszon National Autonomous University of Mexico
Leonard K. Kaczmarek
Leonard K. Kaczmarek Yale University
Christopher J. Lingle
Christopher J. Lingle Washington University in St. Louis
James H. Thomas
James H. Thomas University of Washington
Arthur D. Loewy
Arthur D. Loewy Washington University in St. Louis
Yuh Nung Jan
Yuh Nung Jan University of California, San Francisco
Karen L. O'Malley
Karen L. O'Malley Washington University in St. Louis
Lily Yeh Jan
Lily Yeh Jan University of California, San Francisco

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