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Jesper Q. Svejstrup

Jesper Q. Svejstrup

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Molecular Biology
Denmark
2026

D-Index & Metrics

Molecular Biology

D-Index
75
Citations
16748
World Ranking
1207
National Ranking
9

Research.com Recognitions

  • 2026 - Research.com Molecular Biology in Denmark Leader Award
  • 2009 - Fellow of the Royal Society, United Kingdom
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Jesper Q. Svejstrup is affiliated with the University of Copenhagen in Denmark and specializes in the broad field of Biochemistry, Genetics and Molecular Biology. Their research primarily focuses on Molecular Biology, with additional involvement in Oncology, Cell Biology, Immunology, and Cellular and Molecular Neuroscience.

The scientist's work encompasses several main topics including RNA Research and Splicing, RNA modifications and cancer, Genomics and Chromatin Dynamics, DNA Repair Mechanisms, RNA and protein synthesis mechanisms, CRISPR and Genetic Engineering, and Ubiquitin and proteasome pathways.

Jesper Q. Svejstrup has published extensively, with notable recent papers such as:

  • "Causes and consequences of RNA polymerase II stalling during transcript elongation", 2020, Nature Reviews Molecular Cell Biology
  • "Regulation of the RNAPII Pool Is Integral to the DNA Damage Response", 2020, Cell
  • "The ASC-1 Complex Disassembles Collided Ribosomes", 2020, Molecular Cell
  • "CDK13 cooperates with CDK12 to control global RNA polymerase II processivity", 2020, Science Advances
  • "Using TTchem-seq for profiling nascent transcription and measuring transcript elongation", 2020, Nature Protocols

Frequent co-authors in Jesper Q. Svejstrup's publications include:

  • Richard Mitter
  • A. Barbara Dirac-Svejstrup
  • Zhong Han
  • Daniel Blears
  • Jane Walker

The scientist has appeared in multiple publication venues regularly, with the most common being Molecular Cell, bioRxiv (Cold Spring Harbor Laboratory), Cell, Nature Cell Biology, and DNA Repair.

Jesper Q. Svejstrup has been recognized by several prestigious bodies, holding fellowships and memberships including:

  • Fellow of the Royal Society, United Kingdom, since 2009
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)

Best Publications

  • Relationship of CDK-activating kinase and RNA polymerase II CTD kinase TFIIH/TFIIK

    William J. Feaver;Jesper Q. Svejstrup;N. Lynn Henry;Roger D. Kornberg

  • A Novel Histone Acetyltransferase Is an Integral Subunit of Elongating RNA Polymerase II Holoenzyme

    Birgitte Ø Wittschieben;Gabriel Otero;Therese de Bizemont;Jane Fellows

  • Elongator, a multisubunit component of a novel RNA polymerase II holoenzyme for transcriptional elongation.

    Gabriel Otero;Jane Fellows;Yang Li;Therese de Bizemont

  • Mechanisms of transcription-coupled DNA repair

    Jesper Q Svejstrup

  • Dual roles of a multiprotein complex from S. cerevisiae in transcription and DNA repair

    William J. Feaver;Jesper Q. Svejstrup;Lee Bardwell;A.Jane Bardwell

  • A protein complex containing Tho2, Hpr1, Mft1 and a novel protein, Thp2, connects transcription elongation with mitotic recombination in Saccharomyces cerevisiae

    Sebastian Chavez;Traude Beilharz;Ana G Rondon;Hediye Erdjument-Bromage

  • The multiple roles of transcription/repair factor TFIIH.

    Jesper Q. Svejstrup;Paul Vichi;Jean-Marc Egly

  • Elongator is a histone H3 and H4 acetyltransferase important for normal histone acetylation levels in vivo

    G. Sebastiaan Winkler;Arnold Kristjuhan;Hediye Erdjument-Bromage;Paul Tempst

  • Different forms of TFIIH for transcription and DNA repair: Holo-TFIIH and a nucleotide excision repairosome

    Jesper Q Svejstrup;Zhigang Wang;William J Feave;Xiahua Wu

  • Purification and characterization of the human elongator complex.

    Nicola A. Hawkes;Gabriel Otero;G. Sebastiaan Winkler;Nick Marshall

  • A Rad26–Def1 complex coordinates repair and RNA pol II proteolysis in response to DNA damage

    Elies C. Woudstra;Chris Gilbert;Jane Fellows;Lars Jansen

  • Multiple mechanisms confining RNA polymerase II ubiquitylation to polymerases undergoing transcriptional arrest.

    Baggavalli P. Somesh;James Reid;Wei-Feng Liu;T. Max M. Søgaard

  • Damage-Induced Ubiquitylation of Human RNA Polymerase II by the Ubiquitin Ligase Nedd4, but Not Cockayne Syndrome Proteins or BRCA1

    Roy Anindya;Ozan Aygün;Jesper Q. Svejstrup

  • Transcription Impairment and Cell Migration Defects in Elongator-Depleted Cells: Implication for Familial Dysautonomia

    Pierre Close;Pierre Close;Nicola Hawkes;Isabelle Cornez;Catherine Creppe

  • Transcript Elongation by RNA Polymerase II

    Luke A. Selth;Stefan Sigurdsson;Jesper Q. Svejstrup

  • Evidence for distinct mechanisms facilitating transcript elongation through chromatin in vivo

    Arnold Kristjuhan;Jesper Q Svejstrup

  • RNA polymerase II elongator holoenzyme is composed of two discrete subcomplexes.

    G. Sebastiaan Winkler;Thodoris G. Petrakis;Steen Ethelberg;Masao Tokunaga

  • RNA Polymerase II Collision Interrupts Convergent Transcription

    David J. Hobson;Wu Wei;Lars M. Steinmetz;Jesper Q. Svejstrup

  • Ubiquitylation and degradation of elongating RNA polymerase II: the last resort.

    Marcus D. Wilson;Michelle Harreman;Jesper Q. Svejstrup

  • Elongator complex: how many roles does it play?

    Jesper Q Svejstrup

Frequent Co-Authors

Roger D. Kornberg
Roger D. Kornberg Stanford University
Paul Tempst
Paul Tempst Memorial Sloan Kettering Cancer Center
Hediye Erdjument-Bromage
Hediye Erdjument-Bromage New York University
Ronald C. Conaway
Ronald C. Conaway The University of Texas Southwestern Medical Center
Errol C. Friedberg
Errol C. Friedberg The University of Texas Southwestern Medical Center
Joan Weliky Conaway
Joan Weliky Conaway The University of Texas Southwestern Medical Center
Ambrosius P. Snijders
Ambrosius P. Snijders The Francis Crick Institute
Alain Chariot
Alain Chariot Fonds de la Recherche Scientifique – FNRS
Opher Gileadi
Opher Gileadi Karolinska Institute
Bradley R. Cairns
Bradley R. Cairns University of Utah

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