World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
45
Citations
6895
World Ranking
16508
National Ranking
2525

Overview

Zhen Xi is affiliated with Nankai University in China, with research contributions mainly in the fields of Biochemistry, Genetics and Molecular Biology. Their work spans several subfields including Molecular Biology, Plant Science, Organic Chemistry, Immunology, and Materials Chemistry.

Their research covers a range of topics, as indicated by the thematic focus of their publications. These topics include:

  • Advanced biosensing and bioanalysis techniques
  • Interferon and immune responses
  • Weed control and herbicide applications
  • RNA interference and gene delivery
  • Click chemistry and applications
  • Chemical synthesis and analysis
  • Sulfur compounds in biology

Zhen Xi has contributed to multiple scientific papers across reputable journals. Some recent papers include:

  • "NBD-based synthetic probes for sensing small molecules and proteins: design, sensing mechanisms and biological applications", 2021, Chemical Society Reviews
  • "Cysteine-specific protein multi-functionalization and disulfide bridging using 3-bromo-5-methylene pyrrolones", 2020, Nature Communications
  • "Highly efficient H2S scavengers via thiolysis of positively-charged NBD amines", 2020, Chemical Science
  • "4'-Fluorinated RNA: Synthesis, Structure, and Applications as a Sensitive 19F NMR Probe of RNA Structure and Function", 2020, Journal of the American Chemical Society
  • "(S)-3-(Carboxyformamido)-2-(3-(carboxymethyl)ureido)propanoic Acid as a Novel PSMA Targeting Scaffold for Prostate Cancer Imaging", 2020, Journal of Medicinal Chemistry

Their publication record is also characterized by frequent collaboration with several coauthors. Notable frequent collaborators include:

  • Dejun Ma
  • Long Yi
  • Xin Wen
  • Xueying Kang
  • Chuanzheng Zhou

Regarding publication venues, Zhen Xi has contributed to journals with repeated publications in areas relevant to chemistry and biology. Common venues include:

  • Journal of Agricultural and Food Chemistry (17 publications)
  • ChemBioChem (5 publications)
  • Nature Communications (3 publications)
  • Molecules (3 publications)
  • Chemical Communications (3 publications)

Their scientific activity centers on experimental and synthetic approaches within molecular biology and chemical synthesis fields, addressing biological applications with implications for biosensing, immune response modulation, and chemical probe development. The range of journals and topics reflects interdisciplinary expertise bridging organic chemistry and molecular biology.

Best Publications

  • A Highly Sensitive Fluorescence Probe for Fast Thiol-Quantification Assay of Glutathione Reductase†

    Long Yi;Heyang Li;Lu Sun;Liangliang Liu

  • A new H2S-specific near-infrared fluorescence-enhanced probe that can visualize the H2S level in colorectal cancer cells in mice.

    Kun Zhang;Jie Zhang;Zhen Xi;Lu-Yuan Li

  • NBD-based synthetic probes for sensing small molecules and proteins: design, sensing mechanisms and biological applications

    Chenyang Jiang;Haojie Huang;Xueying Kang;Liu Yang

  • NBD-based colorimetric and fluorescent turn-on probes for hydrogen sulfide

    Chao Wei;Qing Zhu;Weiwei Liu;Wenbin Chen

  • A FRET–ICT dual-quenching fluorescent probe with large off–on response for H2S: synthesis, spectra and bioimaging

    Changyu Zhang;Lv Wei;Chao Wei;Jie Zhang

  • A colorimetric and “turn-on” fluorescent chemosensor for Zn(II) based on coumarin Shiff-base derivative

    He-yang Li;Shuang Gao;Zhen Xi

  • Thiol Specific and Tracelessly Removable Bioconjugation via Michael Addition to 5-Methylene Pyrrolones.

    Yingqian Zhang;Xiaoping Zhou;Yonghui Xie;Marc M. Greenberg

  • A FRET-based fluorescent probe for imaging H2S in living cells

    Chao Wei;Lv Wei;Zhen Xi;Long Yi

  • 5-Formylcytosine Yields DNA–Protein Cross-Links in Nucleosome Core Particles

    Fengchao Li;Yingqian Zhang;Jing Bai;Marc M. Greenberg

  • Thiolysis of NBD-based dyes for colorimetric and fluorescence detection of H2S and biothiols: design and biological applications

    Long Yi;Zhen Xi

  • 7.15 – DNA-damaging Enediyne Compounds

    Zhen Xi;Irving H. Goldberg

  • Design, synthesis, and 3D-QSAR analysis of novel 1,3,4-oxadiazol-2(3H)-ones as protoporphyrinogen oxidase inhibitors

    Li-Li Jiang;Ying Tan;Ying Tan;Xiao-Lei Zhu;Zhi-Fang Wang;Zhi-Fang Wang

  • Probing the function of nucleotides in the catalytic cores of the 8-17 and 10-23 DNAzymes by abasic nucleotide and C3 spacer substitutions.

    Bin Wang;Liqiang Cao;William Chiuman;Yingfu Li

  • A highly selective and fast-response fluorescent probe for visualization of enzymatic H2S production in vitro and in living cells

    Lv Wei;Zhentao Zhu;Yanyan Li;Long Yi

  • Design and Syntheses of Novel Phthalazin-1(2H)-one Derivatives as Acetohydroxyacid Synthase Inhibitors

    Yuan-Xiang Li;Yan-Ping Luo;Zhen Xi;Congwei Niu

  • Design, syntheses and 3D-QSAR studies of novel N-phenyl pyrrolidin-2-ones and N-phenyl-1H-pyrrol-2-ones as protoporphyrinogen oxidase inhibitors

    Li Zhang;Yin Tan;Neng-Xue Wang;Qiong-You Wu

  • Synthesis, Herbicidal Activity, and QSAR of Novel N-Benzothiazolyl- pyrimidine-2,4-diones as Protoporphyrinogen Oxidase Inhibitors

    Yang Zuo;Qiongyou Wu;Sun-wen Su;Cong-wei Niu

  • Design and syntheses of novel N-(benzothiazol-5-yl)-4,5,6,7-tetrahydro-1H-isoindole-1,3(2H)-dione and N-(benzothiazol-5-yl)isoindoline-1,3-dione as potent protoporphyrinogen oxidase inhibitors.

    Li-Li Jiang;Yang Zuo;Zhi-Fang Wang;Yin Tan

  • Structural insight into unique properties of protoporphyrinogen oxidase from Bacillus subtilis.

    Xiaohong Qin;Lu Sun;Xin Wen;Xue Yang

  • A Dual-Response Fluorescent Probe Reveals the H2O2-Induced H2S Biogenesis through a Cystathionine β-Synthase Pathway

    Long Yi;Lv Wei;Runyu Wang;Changyu Zhang

  • Cysteine-specific protein multi-functionalization and disulfide bridging using 3-bromo-5-methylene pyrrolones.

    Yingqian Zhang;Chuanlong Zang;Guoce An;Mengdi Shang

Frequent Co-Authors

Guang-Fu Yang
Guang-Fu Yang Central China Normal University
Zicai Liang
Zicai Liang Peking University
Marc M. Greenberg
Marc M. Greenberg Johns Hopkins University
Michael D. Pluth
Michael D. Pluth University of Oregon
Xiu-Ping Yan
Xiu-Ping Yan Jiangnan University
Xun-Cheng Su
Xun-Cheng Su Nankai University
Qian Peng
Qian Peng Chinese Academy of Sciences
Chang-Guo Zhan
Chang-Guo Zhan University of Kentucky
Rong Xiang
Rong Xiang Nankai University
Jing Wang
Jing Wang Chinese Academy of Sciences

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