Toshihiro Miyamoto

Best Publications

• A clonogenic common myeloid progenitor that gives rise to all myeloid lineages

  Koichi Akashi;Koichi Akashi;David Traver;Toshihiro Miyamoto;Irving L. Weissman

  3456
  Citations

• Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region.

  Fumihiko Ishikawa;Shuro Yoshida;Yoriko Saito;Atsushi Hijikata

  1182
  Citations

• Development of functional human blood and immune systems in NOD/SCID/IL2 receptor γ chainnull mice

  Fumihiko Ishikawa;Masaki Yasukawa;Bonnie Lyons;Shuro Yoshida

  1136
  Citations

• Defucosylated Anti-CCR4 Monoclonal Antibody (KW-0761) for Relapsed Adult T-Cell Leukemia-Lymphoma: A Multicenter Phase II Study

  Takashi Ishida;Tatsuro Joh;Naokuni Uike;Kazuhito Yamamoto

  871
  Citations

• Prospective isolation of human clonogenic common myeloid progenitors

  Markus G. Manz;Toshihiro Miyamoto;Koichi Akashi;Irving L. Weissman

  756
  Citations

• AML1/ETO-expressing nonleukemic stem cells in acute myelogenous leukemia with 8;21 chromosomal translocation

  Toshihiro Miyamoto;Irving L. Weissman;Koichi Akashi;Koichi Akashi

  659
  Citations

• Dendritic cell potentials of early lymphoid and myeloid progenitors.

  Markus G. Manz;David Traver;David Traver;Toshihiro Miyamoto;Toshihiro Miyamoto;Irving L. Weissman;Irving L. Weissman

  593
  Citations

• Development of CD8α-Positive Dendritic Cells from a Common Myeloid Progenitor

  David Traver;Koichi Akashi;Markus Manz;Miriam Merad

  583
  Citations

• TIM-3 Is a Promising Target to Selectively Kill Acute Myeloid Leukemia Stem Cells

  Yoshikane Kikushige;Takahiro Shima;Shin Ichiro Takayanagi;Shingo Urata

  574
  Citations

• Cell-fate conversion of lymphoid-committed progenitors by instructive actions of cytokines

  Motonari Kondo;David C. Scherer;Toshihiro Miyamoto;Angela G. King

  555
  Citations

• Myeloid or Lymphoid Promiscuity as a Critical Step in Hematopoietic Lineage Commitment

  Toshihiro Miyamoto;Hiromi Iwasaki;Boris Reizis;Min Ye

  546
  Citations

• AML1-ETO expression is directly involved in the development of acute myeloid leukemia in the presence of additional mutations

  Youzhong Yuan;Liming Zhou;Toshihiro Miyamoto;Hiromi Iwasaki

  532
  Citations

• Multicenter phase II study of mogamulizumab (KW-0761), a defucosylated anti-cc chemokine receptor 4 antibody, in patients with relapsed peripheral T-cell lymphoma and cutaneous T-cell lymphoma.

  Michinori Ogura;Takashi Ishida;Kiyohiko Hatake;Masafumi Taniwaki

  460
  Citations

• Self-Renewing Hematopoietic Stem Cell Is the Primary Target in Pathogenesis of Human Chronic Lymphocytic Leukemia

  Yoshikane Kikushige;Fumihiko Ishikawa;Toshihiro Miyamoto;Takahiro Shima

  377
  Citations

• The fetal liver counterpart of adult common lymphoid progenitors gives rise to all lymphoid lineages, CD45+CD4+CD3- cells, as well as macrophages.

  Reina E. Mebius;Toshihiro Miyamoto;Julie Christensen;Jos Domen

  344
  Citations

• FLT3-ITD up-regulates MCL-1 to promote survival of stem cells in acute myeloid leukemia via FLT3-ITD–specific STAT5 activation

  Goichi Yoshimoto;Toshihiro Miyamoto;Siamak Jabbarzadeh-Tabrizi;Tadafumi Iino

  330
  Citations

• A TIM-3/Gal-9 Autocrine Stimulatory Loop Drives Self-Renewal of Human Myeloid Leukemia Stem Cells and Leukemic Progression

  Yoshikane Kikushige;Yoshikane Kikushige;Toshihiro Miyamoto;Junichiro Yuda;Siamak Jabbarzadeh-Tabrizi

  324
  Citations

• Persistence of multipotent progenitors expressing AML1/ETO transcripts in long-term remission patients with t(8;21) acute myelogenous leukemia

  Toshihiro Miyamoto;Koji Nagafuji;Koichi Akashi;Mine Harada

  278
  Citations

• Functional expression of Fas antigen (CD95) on hematopoietic progenitor cells

  Koji Nagafuji;Tsunefumi Shibuya;Mine Harada;Shin Ichi Mizuno

  275
  Citations

• Identification of the human eosinophil lineage-committed progenitor: revision of phenotypic definition of the human common myeloid progenitor

  Yasuo Mori;Hiromi Iwasaki;Kentaro Kohno;Goichi Yoshimoto

  255
  Citations