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Hiroaki Niiro

Hiroaki Niiro

D-Index & Metrics

Biology and Biochemistry

D-Index
50
Citations
8804
World Ranking
17657
National Ranking
1273

Overview

Hiroaki Niiro is affiliated with Kyushu University in Japan and has contributed extensively to the fields of medicine and immunology and microbiology. Their research primarily focuses on rheumatology, immunology, genetics, pathology and forensic medicine, as well as pulmonary and respiratory medicine.

The main topics covered in their work include:

  • Systemic Lupus Erythematosus Research
  • Rheumatoid Arthritis Research and Therapies
  • T-cell and B-cell Immunology
  • Monoclonal and Polyclonal Antibodies Research
  • Chronic Lymphocytic Leukemia Research
  • Immune Cell Function and Interaction
  • Vasculitis and related conditions

They have published a number of scientific papers, with recent works including:

  • Meta-analysis of 208370 East Asians identifies 113 susceptibility loci for systemic lupus erythematosus, 2020, Annals of the Rheumatic Diseases
  • Homeostatic Milieu Induces Production of Deoxyribonuclease 1-like 3 from Myeloid Cells, 2020, The Journal of Immunology
  • Biological insights into systemic lupus erythematosus through an immune cell-specific transcriptome-wide association study, 2022, Annals of the Rheumatic Diseases
  • Human PD-1hiCD8+ T Cells Are a Cellular Source of IL-21 in Rheumatoid Arthritis, 2021, Frontiers in Immunology
  • Type 1 helper T cells generate CXCL9/10-producing T-bet+ effector B cells potentially involved in the pathogenesis of rheumatoid arthritis, 2020, Cellular Immunology

Hiroaki Niiro frequently collaborates with several coauthors, including:

  • Masahiro Ayano
  • Koichi Akashi
  • Yasutaka Kimoto
  • Takahiko Horiuchi
  • Hiroki Mitoma

The scientist commonly publishes in the following venues:

  • Modern Rheumatology
  • Frontiers in Immunology
  • Modern Rheumatology Case Reports
  • Annals of the Rheumatic Diseases
  • Arthritis Research & Therapy

Best Publications

  • Regulation of B-cell fate by antigen-receptor signals.

    Hiroaki Niiro;Edward A. Clark

  • Th1/Th2 balance of peripheral T helper cells in systemic lupus erythematosus

    Mitsuteru Akahoshi;Hitoshi Nakashima;Yosuke Tanaka;Tsutomu Kohsaka

  • Self-Renewing Hematopoietic Stem Cell Is the Primary Target in Pathogenesis of Human Chronic Lymphocytic Leukemia

    Yoshikane Kikushige;Fumihiko Ishikawa;Toshihiro Miyamoto;Takahiro Shima

  • FLT3-ITD up-regulates MCL-1 to promote survival of stem cells in acute myeloid leukemia via FLT3-ITD–specific STAT5 activation

    Goichi Yoshimoto;Toshihiro Miyamoto;Siamak Jabbarzadeh-Tabrizi;Tadafumi Iino

  • A TIM-3/Gal-9 Autocrine Stimulatory Loop Drives Self-Renewal of Human Myeloid Leukemia Stem Cells and Leukemic Progression

    Yoshikane Kikushige;Yoshikane Kikushige;Toshihiro Miyamoto;Junichiro Yuda;Siamak Jabbarzadeh-Tabrizi

  • Identification of the human eosinophil lineage-committed progenitor: revision of phenotypic definition of the human common myeloid progenitor

    Yasuo Mori;Hiromi Iwasaki;Kentaro Kohno;Goichi Yoshimoto

  • Regulation by Interleukin-10 and Interleukin-4 of Cyclooxygenase-2 Expression in Human Neutrophils

    Hiroaki Niiro;Takeshi Otsuka;Kenji Izuhara;Kunihiro Yamaoka

  • Human Flt3 Is Expressed at the Hematopoietic Stem Cell and the Granulocyte/Macrophage Progenitor Stages to Maintain Cell Survival

    Yoshikane Kikushige;Goichi Yoshimoto;Toshihiro Miyamoto;Tadafumi Iino;Tadafumi Iino

  • Meta-analysis of 208370 East Asians identifies 113 susceptibility loci for systemic lupus erythematosus

    Xianyong Yin;Kwangwoo Kim;Hiroyuki Suetsugu;So-Young Bang

  • Interaction between Toll-like receptors and natural killer cells in the destruction of bile ducts in primary biliary cirrhosis

    Shinji Shimoda;Kenichi Harada;Hiroaki Niiro;Ken Shirabe

  • Brodalumab, a human anti-interleukin-17-receptor antibody in the treatment of Japanese patients with moderate-to-severe plaque psoriasis: Efficacy and safety results from a phase II randomized controlled study

    Hidemi Nakagawa;Hiroaki Niiro;Kenji Ootaki

  • The developmental program of human dendritic cells is operated independently of conventional myeloid and lymphoid pathways

    Fumihiko Ishikawa;Hiroaki Niiro;Tadafumi Iino;Tadafumi Iino;Shuro Yoshida

  • Inhibition by interleukin-10 of inducible cyclooxygenase expression in lipopolysaccharide-stimulated monocytes: its underlying mechanism in comparison with interleukin-4

    H Niiro;T Otsuka;T Tanabe;S Hara

  • CX3CL1 (fractalkine): A signpost for biliary inflammation in primary biliary cirrhosis

    Shinji Shimoda;Kenichi Harada;Hiroaki Niiro;Akinobu Taketomi

  • Plasmacytoid dendritic cells prime alloreactive T cells to mediate graft-versus-host disease as antigen-presenting cells

    Motoko Koyama;Motoko Koyama;Daigo Hashimoto;Kazutoshi Aoyama;Kazutoshi Aoyama;Ken Ichi Matsuoka

  • MAP kinase pathways as a route for regulatory mechanisms of IL-10 and IL-4 which inhibit COX-2 expression in human monocytes

    Hiroaki Niiro;Takeshi Otsuka;Eiichi Ogami;Kunihiro Yamaoka

  • EFFECT OF IL-10 ON COLLAGEN-INDUCED ARTHRITIS IN MICE

    Y. Tanaka;T. Otsuka;T. Hotokebuchi;H. Miyahara

  • Biliary epithelial cells and primary biliary cirrhosis: the role of liver-infiltrating mononuclear cells.

    Shinji Shimoda;Kenichi Harada;Hiroaki Niiro;Tomoharu Yoshizumi

  • A Novel B Lymphocyte–Associated Adaptor Protein, Bam32, Regulates Antigen Receptor Signaling Downstream of Phosphatidylinositol 3-Kinase

    Aaron J. Marshall;Hiroaki Niiro;Cara G. Lerner;Theodore J. Yun

  • Protection against autoimmune nephritis in MyD88-deficient MRL/lpr mice.

    Atsushi Sadanaga;Hitoshi Nakashima;Mitsuteru Akahoshi;Kohsuke Masutani

Frequent Co-Authors

Koichi Akashi
Koichi Akashi Kyushu University
Toshihiro Miyamoto
Toshihiro Miyamoto Kyushu University
Mine Harada
Mine Harada Kyushu University
Shinji Shimoda
Shinji Shimoda Kyushu University
Yoshiyuki Niho
Yoshiyuki Niho Kyushu University
Kenji Izuhara
Kenji Izuhara Saga Group
Yoshiya Tanaka
Yoshiya Tanaka University of Occupational and Environmental Health Japan
Edward A. Clark
Edward A. Clark University of Washington
M. Eric Gershwin
M. Eric Gershwin University of California, Davis
Hiromi Ishibashi
Hiromi Ishibashi Nagasaki University

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