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Neville E. Sanjana

Neville E. Sanjana

D-Index & Metrics

Biology and Biochemistry

D-Index
51
Citations
37585
World Ranking
16899
National Ranking
6960

Overview

Neville E. Sanjana is affiliated with New York University in the United States and has contributed extensively to the field of biochemistry, genetics, and molecular biology. Their research spans multiple subfields including molecular biology, plant science, immunology, oncology, and artificial intelligence. The breadth of their work reflects a multidisciplinary approach within biological sciences.

The research topics most frequently explored by Sanjana include:

  • CRISPR and Genetic Engineering
  • Single-cell and spatial transcriptomics
  • RNA and protein synthesis mechanisms
  • Advanced biosensing and bioanalysis techniques
  • RNA Research and Splicing
  • Genomics and Chromatin Dynamics
  • RNA modifications and cancer

Among their recent influential papers are:

  • "Identification of Required Host Factors for SARS-CoV-2 Infection in Human Cells" (2020) published in Cell
  • "Autism genes converge on asynchronous development of shared neuron classes" (2022) published in Nature
  • "Massively parallel Cas13 screens reveal principles for guide RNA design" (2020) published in Nature Biotechnology
  • "CRISPR in cancer biology and therapy" (2022) published in Nature reviews. Cancer
  • "The Spike D614G mutation increases SARS-CoV-2 infection of multiple human cell types" (2021) published in eLife

Sanjana collaborates frequently with several researchers, including Hans-Hermann Wessels, Alejandro Méndez-Mancilla, Zharko Daniloski, Mateusz Legut, and Congyi Lu. These collaborations are reflected in numerous coauthored publications, signifying ongoing partnerships in their research ventures.

Their work has been published in a variety of venues, with the most frequent publication platforms being:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Biotechnology
  • Nature Communications
  • Cell Reports
  • Cell

Best Publications

  • Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells

    Ophir Shalem;Ophir Shalem;Neville E Sanjana;Neville E Sanjana;Ella Hartenian;Xi-Shun Shi

  • Improved vectors and genome-wide libraries for CRISPR screening.

    Neville E Sanjana;Ophir Shalem;Feng Zhang

  • High-throughput functional genomics using CRISPR–Cas9

    Ophir Shalem;Ophir Shalem;Neville E. Sanjana;Neville E. Sanjana;Feng Zhang;Feng Zhang

  • Perturbation of m6A Writers Reveals Two Distinct Classes of mRNA Methylation at Internal and 5′ Sites

    Schraga Schwartz;Maxwell R. Mumbach;Marko Jovanovic;Tim Wang;Tim Wang

  • Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening

    Julia Joung;Silvana Konermann;Jonathan S Gootenberg;Omar O Abudayyeh

  • Genome-wide CRISPR screen in a mouse model of tumor growth and metastasis

    Sidi Chen;Sidi Chen;Neville E. Sanjana;Kaijie Zheng;Ophir Shalem

  • A transcription activator-like effector toolbox for genome engineering

    Neville E Sanjana;Le Cong;Le Cong;Le Cong;Yang Zhou;Yang Zhou;Margaret M Cunniff;Margaret M Cunniff

  • BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis

    Matthew C. Canver;Elenoe C. Smith;Falak Sher;Luca Pinello

  • Identification of essential genes for cancer immunotherapy

    Shashank J. Patel;Neville E. Sanjana;Rigel J. Kishton;Arash Eidizadeh

  • Identification of Required Host Factors for SARS-CoV-2 Infection in Human Cells.

    Zharko Daniloski;Tristan X. Jordan;Hans-Hermann Wessels;Daisy A. Hoagland

  • A Genome-wide CRISPR Screen in Primary Immune Cells to Dissect Regulatory Networks

    Oren Parnas;Marko Jovanovic;Thomas M. Eisenhaure;Thomas M. Eisenhaure;Rebecca H. Herbst;Rebecca H. Herbst

  • Multiplexed detection of proteins, transcriptomes, clonotypes and CRISPR perturbations in single cells

    Eleni P. Mimitou;Anthony Cheng;Antonino Montalbano;Stephanie Hao

  • Hypoxia as a therapy for mitochondrial disease

    Isha H. Jain;Luca Zazzeron;Rahul Goli;Rahul Goli;Kristen Alexa

  • CRISPR-Cas component systems, methods and compositions for sequence manipulation

    Feng Zhang;David Olivier Bikard;Le Cong;David Benjamin Turitz Cox

  • Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood

    Julia Joung;Jesse M. Engreitz;Silvana Konermann;Omar O. Abudayyeh

  • Massively parallel Cas13 screens reveal principles for guide RNA design

    Hans-Hermann Wessels;Alejandro Méndez-Mancilla;Xinyi Guo;Mateusz Legut

  • Engineering and optimization of systems, methods and compositions for sequence manipulation with functional domains

    Feng Zhang;Le Cong;Randall Jeffrey Platt;Fei Ran

  • High-resolution interrogation of functional elements in the noncoding genome

    Neville E. Sanjana;Neville E. Sanjana;Jason Wright;Jason Wright;Kaijie Zheng;Kaijie Zheng;Ophir Shalem;Ophir Shalem

  • Genome-wide CRISPR Screen in a Mouse Model of Tumor Growth and Metastasis

    Kyungheon Lee;Jun Song;Ralph Weissleder;Hakho Lee

  • A Genome-wide CRISPR Screen in Primary Immune Cells to Dissect Regulatory Networks

    Oren Parnas;Marko Jovanovic;Thomas M. Eisenhaure;Rebecca H. Herbst

Frequent Co-Authors

Stuart H. Orkin
Stuart H. Orkin Harvard University
Aviv Regev
Aviv Regev Genentech
Luciano A. Marraffini
Luciano A. Marraffini Rockefeller University
Eric S. Lander
Eric S. Lander Broad Institute
Benjamin R. tenOever
Benjamin R. tenOever Icahn School of Medicine at Mount Sinai
Daniel E. Bauer
Daniel E. Bauer Harvard University
Guo-Cheng Yuan
Guo-Cheng Yuan Icahn School of Medicine at Mount Sinai
Nir Hacohen
Nir Hacohen Harvard University

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