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Biology and Biochemistry

D-Index
57
Citations
18616
World Ranking
13563
National Ranking
5750

Overview

Eduardo A. Padlan is affiliated with the National Institutes of Health in the United States. Their research focuses primarily on medicine, with particular emphasis on infectious diseases and related subfields.

Their work addresses various aspects of both animal virus infections and human clinical health challenges. The main topics covered by their research include SARS-CoV-2 and COVID-19 studies, animal virus infection investigations, COVID-19 clinical research, and dental research connected to the COVID-19 pandemic.

Padlan has contributed to academic literature through publications in notable venues such as:

  • eLife
  • Asian Journal of Healthcare Analytics

Recent published papers by Eduardo A. Padlan include:

  • "Identification of a conserved S2 epitope present on spike proteins from all highly pathogenic coronaviruses," 2023, eLife
  • "Knowledge, Perception and Attitude among Dental Students on the Use of Online Education in a Higher Institution of Learning (HEI)," 2023, Asian Journal of Healthcare Analytics

Frequent collaborators in their research efforts have been:

  • Rui P. Silva
  • Yimin Huang
  • Annalee W. Nguyen
  • Ching-Lin Hsieh
  • Oladimeji S. Olaluwoye

Eduardo A. Padlan's research spans a combination of infectious diseases affecting both humans and animals, integrating clinical and veterinary perspectives. Their contributions include examining viral structures related to coronaviruses, as well as educational aspects within dental health disciplines during the COVID-19 era.

Best Publications

  • Conformations of immunoglobulin hypervariable regions.

    Cyrus Chothia;Cyrus Chothia;Arthur M. Lesk;Anna Tramontano;Michael Levitt;Michael Levitt

  • Anatomy of the antibody molecule

    Eduardo A. Padlan

  • Structure of an antibody-antigen complex: crystal structure of the HyHEL-10 Fab-lysozyme complex

    Eduardo A. Padlan;Enid W. Silverton;Steven Sheriff;Gerson H. Cohen

  • Three-dimensional structure of the tryptophan synthase alpha 2 beta 2 multienzyme complex from Salmonella typhimurium.

    C C Hyde;S A Ahmed;E A Padlan;E W Miles

  • Antibody-antigen complexes

    D R Davies;S Sheriff;E A Padlan

  • Grafting of “Abbreviated” Complementarity-Determining Regions Containing Specificity-Determining Residues Essential for Ligand Contact to Engineer a Less Immunogenic Humanized Monoclonal Antibody

    Roberto De Pascalis;Makoto Iwahashi;Midori Tamura;Eduardo A. Padlan

  • Three-Dimensional Structure of Immunoglobulins

    L M Amzel;R J Poljak

  • Three-dimensional structure of an antibody-antigen complex.

    Steven Sheriff;Enid W. Silverton;Eduardo A. Padlan;Gerson H. Cohen

  • Phosphocholine binding immunoglobulin Fab McPC603. An X-ray diffraction study at 2.7 A.

    Yoshinori Satow;Gerson H. Cohen;Eduardo A. Padlan;David R. Davies

  • A possible procedure for reducing the immunogenicity of antibody variable domains while preserving their ligand-binding properties.

    Eduardo A. Padlan

  • The Three-Dimensional Structure of a Phosphorylcholine-Binding Mouse Immunoglobulin Fab and the Nature of the Antigen Binding Site

    David M. Segal;Eduardo A. Padlan;Gerson H. Cohen;Stuart Rudikoff

  • Identification of specificity-determining residues in antibodies.

    Eduardo A. Padlan;Chantal Abergel;Jennifer P. Tipper

  • Structural correlates of an anticarcinoma antibody: identification of specificity-determining residues (SDRs) and development of a minimally immunogenic antibody variant by retention of SDRs only.

    Midori Tamura;Diane E. Milenic;Makoto Iwahashi;Eduardo Padlan

  • Binding of a reduced peptide inhibitor to the aspartic proteinase from Rhizopus chinensis: implications for a mechanism of action

    K. Suguna;Eduardo A. Padlan;Clark W. Smith;William D. Carlson

  • On the nature of antibody combining sites: unusual structural features that may confer on these sites an enhanced capacity for binding ligands

    Eduardo A. Padlan

  • The mast cell binding site on human immunoglobulin E

    B. Helm;P. Marsh;D. Vercelli;E. Padlan

  • X-Ray Crystallography of Antibodies

    Eduardo A. Padlan

  • Structure and refinement at 1.8 A resolution of the aspartic proteinase from Rhizopus chinensis.

    Suguna K;Bott Rr;Padlan Ea;Subramanian E

  • Three-Dimensional Structure of Hemoglobin from the Polychaete Annelid, Glycera dibranchiata, at 2.5 A Resolution

    Eduardo A. Padlan;Warner E. Love

  • Generation, Characterization, and in Vivo Studies of Humanized Anticarcinoma Antibody CC49

    S.V.S. Kashmiri;Liming Shu;Eduardo A. Padlan;Diane E. Milenic

Frequent Co-Authors

David R. Davies
David R. Davies National Institutes of Health
Jeffrey Schlom
Jeffrey Schlom National Institutes of Health
Stuart Rudikoff
Stuart Rudikoff National Institutes of Health
Michael Potter
Michael Potter National Institutes of Health
David M. Segal
David M. Segal University of California, Davis
Diane E. Milenic
Diane E. Milenic National Institutes of Health
Elvin A. Kabat
Elvin A. Kabat Columbia University
Byungkook Lee
Byungkook Lee National Institutes of Health
Itai Benhar
Itai Benhar Tel Aviv University
David H. Margulies
David H. Margulies National Institutes of Health

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