Kenji Kohno

Overview

Best Publications

• Conversion of adult pancreatic α-cells to β-cells after extreme β-cell loss

  Fabrizio Thorel;Virginie Nepote;Isabelle Avril;Kenji Kohno

  1263
  Citations

• Targeted Ablation of Osteocytes Induces Osteoporosis with Defective Mechanotransduction

  Sawako Tatsumi;Kiyoaki Ishii;Norio Amizuka;Minqi Li

  973
  Citations

• The Essential Functions of Adipo-osteogenic Progenitors as the Hematopoietic Stem and Progenitor Cell Niche

  Yoshiki Omatsu;Tatsuki Sugiyama;Hiroshi Kohara;Gen Kondoh

  952
  Citations

• Paneth cells as a site of origin for intestinal inflammation

  Timon E. Adolph;Michal F. Tomczak;Lukas Niederreiter;Hyun Jeong Ko;Hyun Jeong Ko

  821
  Citations

• Podocyte Depletion Causes Glomerulosclerosis: Diphtheria Toxin–Induced Podocyte Depletion in Rats Expressing Human Diphtheria Toxin Receptor Transgene

  Bryan L. Wharram;Meera Goyal;Jocelyn E. Wiggins;Silja K. Sanden

  818
  Citations

• Inhibition of Biosynthesis of Polyisoprenol Sugars in Chick Embryo Microsomes by Tunicamycin

  Akira Takatsuki;Kenji Kohno;Gakuzo Tamura

  585
  Citations

• Diphtheria toxin receptor-mediated conditional and targeted cell ablation in transgenic mice

  Michiko Saito;Takao Iwawaki;Choji Taya;Hiromichi Yonekawa

  563
  Citations

• S. cerevisiae encodes an essential protein homologous in sequence and function to mammalian BiP

  Karl Normington;Kenji Kohno;Yasunori Kozutsumi;Mary-Jane Gething

  519
  Citations

• A 22 bp cis-acting element is necessary and sufficient for the induction of the yeast KAR2 (BiP) gene by unfolded proteins.

  K Mori;A Sant;K Kohno;K Normington

  513
  Citations

• Rapamycin selectively inhibits translation of mRNAs encoding elongation factors and ribosomal proteins

  Naohiro Terada;Hiren R. Patel;Kozo Takase;Kenji Kohno

  464
  Citations

• A transgenic mouse model for monitoring endoplasmic reticulum stress

  Takao Iwawaki;Ryoko Akai;Ryoko Akai;Kenji Kohno;Masayuki Miura;Masayuki Miura

  456
  Citations

• Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability

  Takao Iwawaki;Ryoko Akai;Shinya Yamanaka;Kenji Kohno

  412
  Citations

• The promoter region of the yeast KAR2 (BiP) gene contains a regulatory domain that responds to the presence of unfolded proteins in the endoplasmic reticulum

  K Kohno;K Normington;J Sambrook;M J Gething

  411
  Citations

• Dissociation of Kar2p/BiP from an ER sensory molecule, Ire1p, triggers the unfolded protein response in yeast.

  Katsutomo Okamura;Yukio Kimata;Hironori Higashio;Akio Tsuru

  394
  Citations

• Translational control by the ER transmembrane kinase/ribonuclease IRE1 under ER stress.

  Takao Iwawaki;Akira Hosoda;Tetsuo Okuda;Yusuke Kamigori

  368
  Citations

• Two regulatory steps of ER-stress sensor Ire1 involving its cluster formation and interaction with unfolded proteins

  Yukio Kimata;Yuki Ishiwata-Kimata;Tatsuhiko Ito;Aiko Hirata

  347
  Citations

• Membrane aberrancy and unfolded proteins activate the endoplasmic reticulum stress sensor Ire1 in different ways

  Thanyarat Promlek;Yuki Ishiwata-Kimata;Masahiro Shido;Mitsuru Sakuramoto

  339
  Citations

• A role for BiP as an adjustor for the endoplasmic reticulum stress-sensing protein Ire1

  Yukio Kimata;Daisuke Oikawa;Yusuke Shimizu;Yuki Ishiwata-Kimata

  335
  Citations

• Neurons derived from transplanted neural stem cells restore disrupted neuronal circuitry in a mouse model of spinal cord injury

  Masahiko Abematsu;Keita Tsujimura;Mariko Yamano;Michiko Saito

  331
  Citations

• Translational Pausing Ensures Membrane Targeting and Cytoplasmic Splicing of XBP1u mRNA

  Kota Yanagitani;Yukio Kimata;Hiroshi Kadokura;Kenji Kohno

  323
  Citations