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Medicine

D-Index
84
Citations
23339
World Ranking
15213
National Ranking
580

Overview

Jenneke Klein-Nulend is affiliated with the Academic Center for Dentistry Amsterdam in the Netherlands. Their research spans the interdisciplinary fields of Medicine, Biochemistry, Genetics and Molecular Biology, and Engineering, with a particular focus on Biomedical Engineering, Molecular Biology, Surgery, Genetics, and Biomaterials.

The core areas of their research include Bone Tissue Engineering Materials, Bone Metabolism and Diseases, Bone Health and Osteoporosis Research, Orthopaedic Implants and Arthroplasty, Cellular Mechanics and Interactions, Dental Implant Techniques and Outcomes, and 3D Printing in Biomedical Research.

Jenneke Klein-Nulend has contributed to several recent papers, including:

  • Cellulose and its derivatives: towards biomedical applications (2021) published in Cellulose
  • 3D-printed poly(Ɛ-caprolactone) scaffold with gradient mechanical properties according to force distribution in the mandible for mandibular bone tissue engineering (2020) published in Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials
  • The Osteocyte as the New Discovery of Therapeutic Options in Rare Bone Diseases (2020) published in Frontiers in Endocrinology
  • Is There a Governing Role of Osteocytes in Bone Tissue Regeneration? (2020) published in Current Osteoporosis Reports
  • Inlet flow rate of perfusion bioreactors affects fluid flow dynamics, but not oxygen concentration in 3D-printed scaffolds for bone tissue engineering: Computational analysis and experimental validation (2020) published in Computers in Biology and Medicine

Frequently publishing in specialized scientific venues, Klein-Nulend has multiple publications in Current Osteoporosis Reports, Clinical Implant Dentistry and Related Research, Frontiers in Endocrinology, Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials, and Frontiers in Bioengineering and Biotechnology.

They have collaborated extensively, frequently co-authoring with Jianfeng Jin, Hadi Seddiqi, Astrid D. Bakker, Marco N. Helder, and Behrouz Zandieh-Doulabi.

Jenneke Klein-Nulend has also contributed to book publications, including the title Bioactive Agents for Functionalization of Biomaterials for Precise Tissue Engineering (2023), published by Frontiers Media.

Best Publications

  • Mechanotransduction in bone--role of the lacuno-canalicular network.

    Elisabeth H. Burger;Jenneke Klein-Nulend

  • Cellulose and its derivatives: towards biomedical applications

    Hadi Seddiqi;Erfan Oliaei;Hengameh Honarkar;Jianfeng Jin

  • Adipose tissue-derived mesenchymal stem cell yield and growth characteristics are affected by the tissue-harvesting procedure

    M.J. Oedayrajsingh-Varma;S.M. van Ham;M. Knippenberg;M.N. Helder

  • Pulsating fluid flow increases nitric oxide (NO) synthesis by osteocytes but not periosteal fibroblasts - correlation with prostaglandin upregulation.

    J. Kleinnulend;C.M. Semeins;N.E. Ajubi;P.J. Nijweide

  • Mechanosensation and transduction in osteocytes

    Jenneke Klein-Nulend;Astrid D. Bakker;Rommel G. Bacabac;Aviral Vatsa

  • The production of nitric oxide and prostaglandin E2 by primary bone cells is shear stress dependent

    Astrid D. Bakker;Kazuhisa Soejima;Jenneke Klein-Nulend;Elisabeth H. Burger

  • Mechanical loading and how it affects bone cells: the role of the osteocyte cytoskeleton in maintaining our skeleton.

    J. Klein-Nulend;R.G. Bacabac;A.D. Bakker

  • Mechanobiology of bone tissue

    J. Klein-Nulend;R.G. Bacabac;M.G. Mullender

  • Pulsating fluid flow increases prostaglandin production by cultured chicken osteocytes--a cytoskeleton-dependent process.

    N.E. Ajubi;J. Klein-Nulend;P.J. Nijweide;T. Vrijheid-Lammers

  • Pulsating fluid flow stimulates prostaglandin release and inducible prostaglandin G/H synthase mRNA expression in primary mouse bone cells.

    Jenneke Klein‐Nulend;Elisabeth H. Burger;Cornelis M. Semeins;Lawrence G. Raisz

  • Osteogenesis versus chondrogenesis by BMP-2 and BMP-7 in adipose stem cells.

    M. Knippenberg;M.N. Helder;B. Zandieh Doulabi;P.I.J.M. Wuisman

  • Mechanotransduction of bone cells in vitro: mechanobiology of bone tissue.

    Margriet Mullender;A. J. El Haj;Y. Yang;M. A. van Duin

  • Strain-derived canalicular fluid flow regulates osteoclast activity in a remodelling osteon—a proposal

    Elisabeth H. Burger;Jenneke Klein-Nulend;Theo H. Smit

  • Signal transduction pathways involved in fluid flow-induced PGE2 production by cultured osteocytes

    N. E. Ajubi;N. E. Ajubi;J. Klein-Nulend;M. J. Alblas;E. H. Burger

  • Adipose tissue-derived mesenchymal stem cells acquire bone cell-like responsiveness to fluid shear stress on osteogenic stimulation.

    Marlene Knippenberg;Marco N. Helder;Behrouz Zandieh Doulabi;Cornelis M. Semeins

  • Osteocytes subjected to fluid flow inhibit osteoclast formation and bone resorption.

    S. Djien Tan;Teun J. de Vries;Anne Marie Kuijpers-Jagtman;Cornelis M. Semeins

  • Stem cells from adipose tissue allow challenging new concepts for regenerative medicine.

    Marco N. Helder;Marlene Knippenberg;Marlene Knippenberg;Jenneke Klein-Nulend;Paul I.J.M. Wuisman

  • Osteocyte morphology in fibula and calvaria --- is there a role for mechanosensing?

    Aviral Vatsa;Roel G. Breuls;Cornelis M. Semeins;Philip L. Salmon

  • A comparison of strain and fluid shear stress in stimulating bone cell responses--a computational and experimental study.

    James G. Mcgarry;Jenneke Klein-Nulend;Margriet G. Mullender;Patrick J. Prendergast

  • Expression of serotonin receptors in bone.

    Irene Westbroek;Arie van der Plas;Karien E. de Rooij;Jenneke Klein-Nulend

Frequent Co-Authors

Vincent Everts
Vincent Everts University of Amsterdam
Willem F. Lems
Willem F. Lems Vrije Universiteit Amsterdam
Paul Lips
Paul Lips Vrije Universiteit Amsterdam
Rohit N. Kulkarni
Rohit N. Kulkarni Harvard Medical School
Frank Luyten
Frank Luyten KU Leuven
Fred C. MacKintosh
Fred C. MacKintosh Rice University
Anne Marie Kuijpers-Jagtman
Anne Marie Kuijpers-Jagtman University Medical Center Groningen
Mohammad Ali Shokrgozar
Mohammad Ali Shokrgozar Pasteur Institute of Iran
Erik A. Sistermans
Erik A. Sistermans University of Amsterdam
André G. Uitterlinden
André G. Uitterlinden Erasmus University Rotterdam

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