His primary areas of study are Bone cell, Osteocyte, Cell biology, Internal medicine and Endocrinology. His Bone cell research includes elements of Shear stress, Biophysics, Cell culture and Interstitial fluid. His biological study spans a wide range of topics, including Mechanotransduction, Osteoclast, Bone remodeling and Cytoskeleton.
The study incorporates disciplines such as In vitro, Transduction, Adipose tissue, Bone marrow and Resorption in addition to Cell biology. Jenneke Klein-Nulend has researched Internal medicine in several fields, including Cell signaling and Osteoblast. His work in Endocrinology addresses issues such as Alkaline phosphatase, which are connected to fields such as Fibroblast and Cell growth.
His primary scientific interests are in Bone cell, Cell biology, Endocrinology, Internal medicine and Osteocyte. His Bone cell research includes themes of Cell culture, Biophysics, Bone tissue, Interstitial fluid and Bone remodeling. His work deals with themes such as Adipose tissue, In vitro and Immunology, which intersect with Cell biology.
His study in Endocrinology is interdisciplinary in nature, drawing from both Osteoclast and Osteoblast. His Bone resorption, Proinflammatory cytokine and Prostaglandin study, which is part of a larger body of work in Internal medicine, is frequently linked to Downregulation and upregulation, bridging the gap between disciplines. His research investigates the link between Osteocyte and topics such as Mechanotransduction that cross with problems in Transduction.
Stem cell, Cell biology, Adipose tissue, Osteocyte and Bone regeneration are his primary areas of study. His research combines Osteoclast and Cell biology. The various areas that he examines in his Osteocyte study include Endocrinology, Internal medicine, Bone remodeling, Anatomy and Mechanotransduction.
His work carried out in the field of Endocrinology brings together such families of science as Progenitor cell and Rheumatoid arthritis. His Mechanotransduction research is multidisciplinary, incorporating elements of Matrix, In vitro, Bone cell and Function. Jenneke Klein-Nulend combines subjects such as Dental implant, Stromal vascular fraction, Osteoblast, Bone tissue and Regeneration with his study of Bone regeneration.
His primary areas of investigation include Osteocyte, Adipose tissue, Cell biology, Endocrinology and Internal medicine. He has included themes like Mechanotransduction, Bone remodeling and Age related in his Osteocyte study. The concepts of his Adipose tissue study are interwoven with issues in Mesenchymal stem cell, Bone regeneration and Stem cell.
The Cell biology study combines topics in areas such as Anabolism and Protein biosynthesis. His Endocrinology study incorporates themes from Proinflammatory cytokine and Cytokine. His work on Bone cell and Immunohistochemistry as part of general Internal medicine study is frequently linked to Lactation and Downregulation and upregulation, bridging the gap between disciplines.
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Mechanotransduction in bone--role of the lacuno-canalicular network.
Elisabeth H. Burger;Jenneke Klein-Nulend.
The FASEB Journal (1999)
Sensitivity of osteocytes to biomechanical stress in vitro.
J Klein-Nulend;A van der Plas;C M Semeins;N E Ajubi.
The FASEB Journal (1995)
Adipose tissue-derived mesenchymal stem cell yield and growth characteristics are affected by the tissue-harvesting procedure
M.J. Oedayrajsingh-Varma;S.M. van Ham;M. Knippenberg;M.N. Helder.
Cytotherapy (2006)
Pulsating fluid flow increases nitric oxide (NO) synthesis by osteocytes but not periosteal fibroblasts - correlation with prostaglandin upregulation.
J. Kleinnulend;C.M. Semeins;N.E. Ajubi;P.J. Nijweide.
Biochemical and Biophysical Research Communications (1995)
Mechanosensation and transduction in osteocytes
Jenneke Klein-Nulend;Astrid D. Bakker;Rommel G. Bacabac;Aviral Vatsa.
Bone (2013)
The production of nitric oxide and prostaglandin E2 by primary bone cells is shear stress dependent
Astrid D. Bakker;Kazuhisa Soejima;Jenneke Klein-Nulend;Elisabeth H. Burger.
Journal of Biomechanics (2001)
Mechanobiology of bone tissue
J. Klein-Nulend;R.G. Bacabac;M.G. Mullender.
Pathologie Biologie (2005)
Pulsating fluid flow increases prostaglandin production by cultured chicken osteocytes--a cytoskeleton-dependent process.
N.E. Ajubi;J. Klein-Nulend;P.J. Nijweide;T. Vrijheid-Lammers.
Biochemical and Biophysical Research Communications (1996)
Pulsating fluid flow stimulates prostaglandin release and inducible prostaglandin G/H synthase mRNA expression in primary mouse bone cells.
Jenneke Klein‐Nulend;Elisabeth H. Burger;Cornelis M. Semeins;Lawrence G. Raisz.
Journal of Bone and Mineral Research (1997)
Osteogenesis versus chondrogenesis by BMP-2 and BMP-7 in adipose stem cells.
M. Knippenberg;M.N. Helder;B. Zandieh Doulabi;P.I.J.M. Wuisman.
Biochemical and Biophysical Research Communications (2006)
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