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D-Index & Metrics

Chemistry

D-Index
68
Citations
13431
World Ranking
6694
National Ranking
2013

Biology and Biochemistry

D-Index
71
Citations
15349
World Ranking
6763
National Ranking
3132

Research.com Recognitions

  • 2012 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

David P. Giedroc is affiliated with Indiana University in the United States. Their research primarily falls within the field of Biochemistry, Genetics, and Molecular Biology, with specific contributions to Molecular Biology, Nutrition and Dietetics, Biochemistry, Genetics, and Molecular Medicine.

The scientist has authored papers addressing a range of topics including Trace Elements in Health, Sulfur Compounds in Biology, RNA and protein synthesis mechanisms, Bacterial Genetics and Biotechnology, Antibiotic Resistance in Bacteria, Bacterial biofilms and quorum sensing, as well as Gut microbiota and health.

Notable recent papers include:

  • Cell-free biosensors for rapid detection of water contaminants (2020) published in Nature Biotechnology
  • Zn-regulated GTPase metalloprotein activator 1 modulates vertebrate zinc homeostasis (2022) published in Cell
  • H2S and reactive sulfur signaling at the host-bacterial pathogen interface (2020) published in Journal of Biological Chemistry
  • Clostridioides difficile Senses and Hijacks Host Heme for Incorporation into an Oxidative Stress Defense System (2020) published in Cell Host & Microbe
  • Molecular Evolution of Transition Metal Bioavailability at the Host-Pathogen Interface (2020) published in Trends in Microbiology

Frequent co-authors include Daiana A. Capdevila, Katherine A. Edmonds, Eric P. Skaar, Yifan Zhang, and Giovanni González-Gutiérrez.

Publication venues that have appeared regularly in their work include bioRxiv (Cold Spring Harbor Laboratory), Journal of Biological Chemistry, Cell Host & Microbe, mBio, and Biophysical Journal.

David P. Giedroc was named a Fellow of the American Association for the Advancement of Science (AAAS) in 2012.

Best Publications

  • Coordination chemistry of bacterial metal transport and sensing.

    Zhen Ma;Faith E. Jacobsen;David P. Giedroc

  • The RNA Molecule CsrB Binds to the Global Regulatory Protein CsrA and Antagonizes Its Activity in Escherichia coli

    Mu Ya Liu;Gaojun Gui;Bangdong Wei;James F. Preston

  • The SmtB/ArsR family of metalloregulatory transcriptional repressors: Structural insights into prokaryotic metal resistance

    Laura S. Busenlehner;Mario A. Pennella;David P. Giedroc

  • CsoR is a novel Mycobacterium tuberculosis copper-sensing transcriptional regulator

    Tong Liu;Arati Ramesh;Zhen Ma;Sarah K Ward

  • Cell-free biosensors for rapid detection of water contaminants

    Jaeyoung K. Jung;Khalid K. Alam;Matthew S. Verosloff;Daiana A. Capdevila

  • Frameshifting RNA pseudoknots: Structure and mechanism

    David P. Giedroc;Peter V. Cornish

  • Structure, stability and function of RNA pseudoknots involved in stimulating ribosomal frameshifting

    David P Giedroc;Carla A Theimer;Paul L Nixon

  • Metal sensor proteins: nature's metalloregulated allosteric switches.

    David P. Giedroc;David P. Giedroc;Alphonse I. Arunkumar;Alphonse I. Arunkumar

  • Recombinant HIV-1 nucleocapsid protein accelerates HIV-1 reverse transcriptase catalyzed DNA strand transfer reactions and modulates RNase H activity.

    James A. Peliska;Shankar Balasubramanian;Shankar Balasubramanian;Shankar Balasubramanian;David P. Giedroc;David P. Giedroc;Stephen J. Benkovic

  • Metal response element (MRE)-binding transcription factor-1 (MTF-1): structure, function, and regulation.

    David P. Giedroc;Xiaohua Chen;Julius L. Apuy

  • Recombinant human immunodeficiency virus type 1 nucleocapsid (NCp7) protein unwinds tRNA.

    R Khan;D.P. Giedroc

  • Metalloregulatory proteins: metal selectivity and allosteric switching.

    Hermes Reyes-Caballero;Gregory C. Campanello;David P. Giedroc

  • Gene 32 protein, the single-stranded DNA binding protein from bacteriophage T4, is a zinc metalloprotein.

    David P. Giedroc;Kathleen M. Keating;Kenneth R. Williams;William H. Konigsberg

  • Structural determinants of metal selectivity in prokaryotic metal-responsive transcriptional regulators.

    Mario A Pennella;David P Giedroc

  • Bacterial Strategies to Maintain Zinc Metallostasis at the Host-Pathogen Interface

    Daiana A. Capdevila;Jiefei Wang;David P. Giedroc

  • Coronavirus N protein N-terminal domain (NTD) specifically binds the transcriptional regulatory sequence (TRS) and melts TRS-cTRS RNA duplexes

    Nicholas E. Grossoehme;Lichun Li;Sarah C. Keane;Pinghua Liu

  • Elucidation of Primary (α3N) and Vestigial (α5) Heavy Metal-binding Sites in Staphylococcus aureus pI258 CadC: Evolutionary Implications for Metal Ion Selectivity of ArsR/SmtB Metal Sensor Proteins

    Laura S. Busenlehner;Tsu Chien Weng;James E. Penner-Hahn;David P. Giedroc

  • A nickel-cobalt-sensing ArsR-SmtB family repressor. Contributions of cytosol and effector binding sites to metal selectivity.

    Jennifer S. Cavet;Wenmao Meng;Mario A. Pennella;Rebecca J. Appelhoff

  • Manganese acquisition and homeostasis at the host-pathogen interface.

    John P Lisher;David P Giedroc

  • Interplay between manganese and zinc homeostasis in the human pathogen Streptococcus pneumoniae

    Faith E. Jacobsen;Krystyna M. Kazmierczak;John P. Lisher;Malcolm E. Winkler

  • A metal-ligand-mediated intersubunit allosteric switch in related SmtB/ArsR zinc sensor proteins.

    Christoph Eicken;Mario A. Pennella;Xiaohua Chen;Karl M. Koshlap

Frequent Co-Authors

Eric P. Skaar
Eric P. Skaar Vanderbilt University Medical Center
Robert A. Scott
Robert A. Scott University of Cambridge
Julian L. Leibowitz
Julian L. Leibowitz Texas A&M University
Malcolm E. Winkler
Malcolm E. Winkler Indiana University
David Puett
David Puett University of Georgia
Kenneth R. Williams
Kenneth R. Williams Yale University
Nicholas Ling
Nicholas Ling Salk Institute for Biological Studies
Carl E. Bauer
Carl E. Bauer Indiana University
Walter J. Chazin
Walter J. Chazin Vanderbilt University

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