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Marie-Paule Lefranc

Marie-Paule Lefranc

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Genetics
France
2024
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Genetics and Molecular Biology
France
2024

D-Index & Metrics

Immunology

D-Index
93
Citations
33807
World Ranking
961
National Ranking
33

Genetics

D-Index
92
Citations
32469
World Ranking
998
National Ranking
30

Research.com Recognitions

  • 2024 - Research.com Genetics in France Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in France Leader Award

Overview

Marie-Paule Lefranc is affiliated with the University of Montpellier in France. Their research primarily spans Immunology and Microbiology, Biochemistry, Genetics and Molecular Biology, and Medicine. Within these broader fields, the scientist focuses on subfields such as Immunology, Molecular Biology, Radiology, Nuclear Medicine and Imaging, Genetics, and Ocean Engineering.

The main topics of research covered include T-cell and B-cell Immunology, Monoclonal and Polyclonal Antibodies Research, Immune Cell Function and Interaction, Immunodeficiency and Autoimmune Disorders, vaccines and immunoinformatics approaches, Aquaculture disease management and microbiota, and Glycosylation and Glycoproteins Research.

Their recent notable publications include:

  • Genotype and functional correlates of disease phenotype in deficiency of adenosine deaminase 2 (DADA2), 2020, Journal of Allergy and Clinical Immunology
  • Higher-order connections between stereotyped subsets: implications for improved patient classification in CLL, 2020, Blood
  • Immunoglobulins or Antibodies: IMGT® Bridging Genes, Structures and Functions, 2020, Biomedicines
  • Evolution of the T-Cell Receptor (TR) Loci in the Adaptive Immune Response: The Tale of the TRG Locus in Mammals, 2020, Genes
  • Topology and expressed repertoire of the Felis catus T cell receptor loci, 2020, BMC Genomics

Frequent co-authors contributing to their work include Sofia Kossida, Géraldine Folch, Véronique Giudicelli, Gérard Lefranc, and André Mégarbané.

The scientist has published multiple works in leading venues such as Frontiers in Immunology, Genes, Methods in Molecular Biology, Clinical Immunology, and Developmental & Comparative Immunology.

Best Publications

  • IMGT/V-QUEST: the highly customized and integrated system for IG and TR standardized V-J and V-D-J sequence analysis

    Xavier Brochet;Marie-Paule Lefranc;Véronique Giudicelli

  • IMGT®, the international ImMunoGeneTics information system®

    Marie-Paule Lefranc;Véronique Giudicelli;Chantal Ginestoux;Joumana Jabado-Michaloud

  • IMGT unique numbering for immunoglobulin and T cell receptor variable domains and Ig superfamily V-like domains.

    Marie-Paule Lefranc;Christelle Pommié;Quentin Kaas;Elodie Duprat

  • IMGT, the international ImMunoGeneTics database.

    Marie-Paule Lefranc

  • IMGT, the international ImMunoGeneTics information system®

    Unknown

  • IMGT unique numbering for immunoglobulin and T cell receptor variable domains and Ig superfamily V-like domains.

    Unknown

  • IMGT, the international ImMunoGeneTics database

    Unknown

  • IMGT®, the international ImMunoGeneTics information system® 25 years on

    Marie-Paule Lefranc;Véronique Giudicelli;Patrice Duroux;Joumana Jabado-Michaloud

  • IMGT(®) tools for the nucleotide analysis of immunoglobulin (IG) and T cell receptor (TR) V-(D)-J repertoires, polymorphisms, and IG mutations: IMGT/V-QUEST and IMGT/HighV-QUEST for NGS.

    Eltaf Alamyar;Patrice Duroux;Marie-Paule Lefranc;Véronique Giudicelli

  • IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes

    Véronique Giudicelli;Denys Chaume;Marie-Paule Lefranc

  • Two tandemly organized human genes encoding the T-cell gamma constant-region sequences show multiple rearrangement in different T-cell types.

    Marie-Paule Lefranc;T. H. Rabbitts

  • Stereotyped B-cell receptors in one-third of chronic lymphocytic leukemia: a molecular classification with implications for targeted therapies

    Andreas Agathangelidis;Nikos Darzentas;Anastasia Hadzidimitriou;Xavier Brochet

  • The Immunoglobulin FactsBook

    Marie-Paule Lefranc;Gérard Lefranc

  • Diversity and rearrangement of the human T cell rearranging γ genes: nine germ-line variable genes belonging to two subgroups

    M.-P. LeFranc;A. Forster;R. Baer;M.A. Stinson

  • Human Ig superfamily CTLA-4 gene: chromosomal localization and identity of protein sequence between murine and human CTLA-4 cytoplasmic domains.

    Piona Dariavach;Marie-Geneviève Mattéi;Pierre Golstein;Marie-Paule Lefranc

  • IMGT/JunctionAnalysis: the first tool for the analysis of the immunoglobulin and T cell receptor complex V--J and V--D--J JUNCTIONs

    Mehdi Yousfi Monod;Véronique Giudicelli;Denys Chaume;Marie-Paule Lefranc

  • IMGT/V-QUEST, an integrated software program for immunoglobulin and T cell receptor V-J and V-D-J rearrangement analysis.

    Véronique Giudicelli;Denys Chaume;Marie-Paule Lefranc

  • IMGT/V-QUEST: IMGT standardized analysis of the immunoglobulin (IG) and T cell receptor (TR) nucleotide sequences.

    Véronique Giudicelli;Xavier Brochet;Marie-Paule Lefranc

  • IMGT standardized criteria for statistical analysis of immunoglobulin V-REGION amino acid properties.

    Christelle Pommié;Séverine Levadoux;Robert Sabatier;Gérard Lefranc

  • Human immunoglobulin allotypes: possible implications for immunogenicity.

    Roy Jefferis;Marie-Paule Lefranc

  • IMGT/LIGM-DB, the IMGT® comprehensive database of immunoglobulin and T cell receptor nucleotide sequences

    Véronique Giudicelli;Patrice Duroux;Chantal Ginestoux;Géraldine Folch

  • Sequence and evolution of the human germline V lambda repertoire.

    Samuel C. Williams;Jean-Pol Frippiat;Jean-Pol Frippiat;Ian M. Tomlinson;Ian M. Tomlinson;Olga Ignatovich;Olga Ignatovich

  • IMGT/3Dstructure-DB and IMGT/DomainGapAlign: a database and a tool for immunoglobulins or antibodies, T cell receptors, MHC, IgSF and MhcSF

    François Ehrenmann;Quentin Kaas;Marie-Paule Lefranc

Frequent Co-Authors

Gérard Lefranc
Gérard Lefranc University of Montpellier
Richard Rosenquist
Richard Rosenquist Karolinska Institute
Terence H. Rabbitts
Terence H. Rabbitts Institute of Cancer Research
Frederic Davi
Frederic Davi Assistance Publique – Hôpitaux de Paris
Šárka Pospíšilová
Šárka Pospíšilová Masaryk University
Paolo Ghia
Paolo Ghia Vita-Salute San Raffaele University
David Oscier
David Oscier Royal Bournemouth Hospital
Kostas Stamatopoulos
Kostas Stamatopoulos Centre for Research and Technology Hellas
Anton W. Langerak
Anton W. Langerak Erasmus University Rotterdam
Pierre Boudinot
Pierre Boudinot Versailles Saint-Quentin-en-Yvelines University

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