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Chemistry

D-Index
61
Citations
10286
World Ranking
9476
National Ranking
2661

Research.com Recognitions

  • 1997 - Fellow of the Royal Society of Canada Academy of Science

Overview

James E. Bruce is affiliated with the University of Washington in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology as well as Chemistry. Within these broad domains, they have focused extensively on Molecular Biology and Spectroscopy, with additional investigations in Cardiology and Cardiovascular Medicine, Insect Science, and Computational Theory and Mathematics.

The scientist's work covers a number of specific topics including Mass Spectrometry Techniques and Applications, Advanced Proteomics Techniques and Applications, Mitochondrial Function and Pathology, Protein Structure and Dynamics, Metabolomics and Mass Spectrometry Studies, Bioinformatics and Genomic Networks, and RNA and Protein Synthesis Mechanisms.

James E. Bruce has contributed to several recent papers:

  • Towards a structurally resolved human protein interaction network, 2023, Nature Structural & Molecular Biology
  • Mitochondrial protein interaction landscape of SS-31, 2020, Proceedings of the National Academy of Sciences
  • Crosslinking mass spectrometry: A link between structural biology and systems biology, 2021, Protein Science
  • Isobaric Quantitative Protein Interaction Reporter Technology for Comparative Interactome Studies, 2020, Analytical Chemistry
  • Quantitative interactome analysis with chemical cross-linking and mass spectrometry, 2021, Current Opinion in Chemical Biology

The scientist has published frequently in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Proteome Research
  • Analytical Chemistry
  • Molecular & Cellular Proteomics
  • Current Biology

Their work involves collaboration with several frequent co-authors such as Andrew Keller, Juan D. Chavez, Anna Bakhtina, Helisa H. Wippel, and Xiaoting Tang.

James E. Bruce was recognized as a Fellow of the Royal Society of Canada in 1997. The citation for this award is from the Academy of Science.

Best Publications

  • Normalization of NAD+ Redox Balance as a Therapy for Heart Failure.

    Chi Fung Lee;Juan D. Chavez;Lorena Garcia-Menendez;Yong Seon Choi

  • Towards a structurally resolved human protein interaction network

    Unknown

  • Probing proteomes using capillary isoelectric focusing-electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry.

    Pamela K. Jensen;Ljiljana Paša-Tolić;Gordon A. Anderson;Julie A. Horner

  • High-resolution accurate mass measurements of biomolecules using a new electrospray ionization ion cyclotron resonance mass spectrometer.

    Brian E. Winger;Steven A. Hofstadler;James E. Bruce;Harold R. Udseth

  • Mass Spectrometry Identifiable Cross-Linking Strategy for Studying Protein−Protein Interactions

    Xiaoting Tang;Gerhard R. Munske;William F. Siems;James E. Bruce

  • High throughput proteome-wide precision measurements of protein expression using mass spectrometry

    Ljiljana Paša-Tolic;Pamela K. Jensen;Gordon A. Anderson;Mary S. Lipton

  • Using Electrospray Ionization FTICR Mass Spectrometry To Study Competitive Binding of Inhibitors to Carbonic Anhydrase

    Xueheng Cheng;Ruidan Chen;James E. Bruce;Brenda L. Schwartz

  • New mass spectrometric methods for the study of noncovalent associations of biopolymers

    Richard D. Smith;James E. Bruce;Qinyuan Wu;Q. Paula Lei

  • Screening derivatized peptide libraries for tight binding inhibitors to carbonic anhydrase II by electrospray ionization-mass spectrometry.

    Jinming Gao;Xueheng Cheng;Ruidan Chen;George B. Sigal

  • Mitochondrial protein interactome elucidated by chemical cross-linking mass spectrometry

    Devin K. Schweppe;Juan D. Chavez;Chi Fung Lee;Arianne Caudal

  • Protein Identification with a Single Accurate Mass of a Cysteine-Containing Peptide and Constrained Database Searching

    David R. Goodlett;James E. Bruce;Gordon A. Anderson;Beate Rist

  • Identification of Protein-Protein Interactions and Topologies in Living Cells with Chemical Cross-linking and Mass Spectrometry

    Haizhen Zhang;Xiaoting Tang;Gerhard R. Munske;Nikola Tolic

  • A new cross-linking strategy: protein interaction reporter (PIR) technology for protein–protein interaction studies

    Xiaoting Tang;James E. Bruce

  • Mitochondrial protein interaction landscape of SS-31

    Juan D. Chavez;Xiaoting Tang;Matthew D. Campbell;Gustavo Reyes

  • Dissociation of tetrameric ions of noncovalent streptavidin complexes formed by electrospray ionization.

    Brenda L. Schwartz;James E. Bruce;Gordon A. Anderson;Steven A. Hofstadler

  • Chemical Crosslinking Mass Spectrometry Analysis of Protein Conformations and Supercomplexes in Heart Tissue

    Juan D. Chavez;Chi Fung Lee;Arianne Caudal;Andrew Keller

  • Accurate mass multiplexed tandem mass spectrometry for high-throughput polypeptide identification from mixtures.

    Christophe Masselon;Gordon A. Anderson;Richard Harkewicz;James E. Bruce

  • In vivo protein interaction network identified with a novel real-time cross-linked peptide identification strategy.

    Chad R. Weisbrod;Juan D. Chavez;Jimmy K. Eng;Li Yang

  • Chemical cross-linking with mass spectrometry: a tool for systems structural biology.

    Juan D Chavez;James E Bruce

  • First Community-Wide, Comparative Cross-Linking Mass Spectrometry Study.

    Claudio Iacobucci;Christine Piotrowski;Ruedi Aebersold;Ruedi Aebersold;Bruno C. Amaral

  • Identification of intrinsic order and disorder in the DNA repair protein XPA

    Lilia M. Iakoucheva;Amy L. Kimzey;Christophe D. Masselon;James E. Bruce

  • Isotope distribution encoded tags for protein identification

    David R. Goodlett;James E. Bruce;Beate Rist;Richard D. Smith

  • Protein Interactions, Post-translational Modifications and Topologies in Human Cells

    Juan D. Chavez;Chad R. Weisbrod;Chunxiang Zheng;Jimmy K. Eng

  • Carbonic Anhydrase-Inhibitor Binding: From Solution to the Gas Phase

    Qinyuan Wu;Jinming Gao;Diane Joseph-McCarthy;George B. Sigal

Frequent Co-Authors

Richard D. Smith
Richard D. Smith Pacific Northwest National Laboratory
Gordon A. Anderson
Gordon A. Anderson Pacific Northwest National Laboratory
Jimmy K. Eng
Jimmy K. Eng University of Washington
Pradeep K. Singh
Pradeep K. Singh University of Washington
Ljiljana Paša-Tolić
Ljiljana Paša-Tolić Environmental Molecular Sciences Laboratory
Colin Manoil
Colin Manoil University of Washington
John D. Scott
John D. Scott University of Washington
Stewart M. Gray
Stewart M. Gray Cornell University
Michael J. MacCoss
Michael J. MacCoss University of Washington

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