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D-Index & Metrics

Biology and Biochemistry

D-Index
69
Citations
15733
World Ranking
7456
National Ranking
3397

Overview

Lan Huang is affiliated with the University of California, Irvine in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a total of over 250 publications across these fields.

The subfields of study in which they have contributed significantly include Molecular Biology, Oncology, Cell Biology, Spectroscopy, and Genetics.

The main research topics that Lan Huang has addressed involve:

  • Ubiquitin and proteasome pathways
  • Neutropenia and cancer infections
  • Blood disorders and treatments
  • Advanced proteomics techniques and applications
  • Cancer treatment and pharmacology
  • Biotin and related studies
  • Mass spectrometry techniques and applications

Lan Huang has co-authored extensively with several researchers. Frequent collaborators include Clinton Yu, Ramon Mohanlal, Douglas W. Blayney, Xiaorong Wang, and Scott D. Rychnovsky.

Their publication record shows a pattern of frequent contributions to certain academic venues. These include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Clinical Oncology
  • Nature Communications
  • Analytical Chemistry
  • Proceedings of the National Academy of Sciences

Recent notable publications by Lan Huang are:

  • "PAM-less plant genome editing using a CRISPR-SpRY toolbox," 2021, published in Nature Plants
  • "Expanding the scope of plant genome engineering with Cas12a orthologs and highly multiplexable editing systems," 2021, published in Nature Communications
  • "Protein interaction landscapes revealed by advanced in vivo cross-linking-mass spectrometry," 2021, published in Proceedings of the National Academy of Sciences
  • "Improved plant cytosine base editors with high editing activity, purity, and specificity," 2021, published in Plant Biotechnology Journal
  • "Structural dynamics of the human COP9 signalosome revealed by cross-linking mass spectrometry and integrative modeling," 2020, published in Proceedings of the National Academy of Sciences

Best Publications

  • Stress-inducible protein 1 is a cell surface ligand for cellular prion that triggers neuroprotection

    Silvio M. Zanata;Marilene H. Lopes;Adriana F. Mercadante;Glaucia N. M. Hajj

  • A Tandem Affinity Tag for Two-step Purification under Fully Denaturing Conditions Application in Ubiquitin Profiling and Protein Complex Identification Combined with in vivoCross-Linking

    Christian Tagwerker;Karin Flick;Meng Cui;Cortnie Guerrero

  • Development of a Novel Cross-linking Strategy for Fast and Accurate Identification of Cross-linked Peptides of Protein Complexes

    Athit Kao;Chi-li Chiu;Danielle Vellucci;Yingying Yang

  • IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome

    Leslie Michels Thompson;Charity T. Aiken;Linda S. Kaltenbach;Namita Agrawal

  • Patterns of Protein Synthesis and Tolerance of Anoxia in Root Tips of Maize Seedlings Acclimated to a Low-Oxygen Environment, and Identification of Proteins by Mass Spectrometry

    William W.P. Chang;Lan Huang;Min Shen;Cecelia Webster

  • Cross-Linking Mass Spectrometry: An Emerging Technology for Interactomics and Structural Biology.

    Clinton Yu;Lan Huang

  • An Integrated Mass Spectrometry-based Proteomic Approach Quantitative Analysis of Tandem Affinity-purified in vivo Cross-linked Protein Complexes (qtax) to Decipher the 26 s Proteasome-interacting Network

    Cortnie Guerrero;Christian Tagwerker;Christian Tagwerker;Peter Kaiser;Lan Huang

  • Oxidative Stress-Mediated Regulation of Proteasome Complexes

    Charity T. Aiken;Robyn M. Kaake;Xiaorong Wang;Lan Huang

  • ERK phosphorylation drives cytoplasmic accumulation of hnRNP-K and inhibition of mRNA translation

    Hasem Habelhah;Kavita Shah;Lan Huang;Antje Ostareck-Lederer

  • Structural basis for the interaction of Ras with RalGDS.

    L Huang;F Hofer;G S Martin;S H Kim

  • Mass Spectrometric Characterization of the Affinity-Purified Human 26S Proteasome Complex†

    Xiaorong Wang;Chi-Fen Chen;Peter R Baker;Phang-lang Chen

  • Regulation of the 26S Proteasome Complex During Oxidative Stress

    Xiaorong Wang;James Yen;Peter Kaiser;Lan Huang

  • Proteomic Analysis of Nucleoporin Interacting Proteins

    Nadia P.C. Allen;Lan Huang;Al Burlingame;Michael Rexach

  • Quantitative Analysis of global Ubiquitination in HeLa Cells by Mass Spectrometry

    David Meierhofer;David Meierhofer;Xiaorong Wang;Lan Huang;Peter Kaiser

  • Comprehensive analysis of a multidimensional liquid chromatography mass spectrometry dataset acquired on a quadrupole selecting, quadrupole collision cell, time-of-flight mass spectrometer: II. New developments in Protein Prospector allow for reliable and comprehensive automatic analysis of large datasets.

    Robert J. Chalkley;Peter R. Baker;Lan Huang;Kirk C. Hansen

  • Histone Acetylation and Deacetylation Identification of Acetylation and Methylation Sites of HeLa Histone H4 by Mass Spectrometry

    Kangling Zhang;Kangling Zhang;Katherine E. Williams;Lan Huang;Peter Yau

  • Phospho-Dependent Functional Modulation of GABAB Receptors by the Metabolic Sensor AMP-Dependent Protein Kinase

    Nobuyuki Kuramoto;Megan E. Wilkins;Benjamin P. Fairfax;Raquel Revilla-Sanchez

  • Identifying dynamic interactors of protein complexes by quantitative mass spectrometry

    Xiaorong Wang;Lan Huang

  • Identification of acetylation and methylation sites of histone H3 from chicken erythrocytes by high-accuracy matrix-assisted laser desorption ionization-time-of-flight, matrix-assisted laser desorption ionization-postsource decay, and nanoelectrospray ionization tandem mass spectrometry.

    Kangling Zhang;Kangling Zhang;Hui Tang;Lan Huang;James W. Blankenship

  • Phosphorylation of threonine 3: implications for Huntingtin aggregation and neurotoxicity.

    Charity T. Aiken;Joan S. Steffan;Cortnie M. Guerrero;Hasan Khashwji

Frequent Co-Authors

Scott D. Rychnovsky
Scott D. Rychnovsky University of California, Irvine
Peter K. Kaiser
Peter K. Kaiser Cleveland Clinic
Alma L. Burlingame
Alma L. Burlingame University of California, San Francisco
Robert T. Kennedy
Robert T. Kennedy University of Michigan–Ann Arbor
Hong-Cai Zhou
Hong-Cai Zhou Texas A&M University
Pierre Baldi
Pierre Baldi University of California, Irvine
Andrej Sali
Andrej Sali University of California, San Francisco
Jun-Sheng Qin
Jun-Sheng Qin Jilin University
Robert J. Chalkley
Robert J. Chalkley University of California, San Francisco
Tahir Cagin
Tahir Cagin Texas A&M University

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